Research database
SVF Research Library
Search 52,792 real PubMed studies on SVF and adipose-derived stem cells — 17 matching records.
17 results — page 1 of 1
- Level DAnimal StudyPubMed
Extracellular vesicles secreted by adipose-derived stem cells alleviate dedifferentiation and senescence in monolayer-expanded chondrocytes by suppressing interleukin-1β-induced MAPK signaling.
Animal Study on Cartilage Damage, published in Cell Transplant (2026) — summary generated from the PubMed abstract.
- 2026
Cell Transplant - Level DAnimal StudyPubMed
Tβ4-Engineered ADSC Extracellular Vesicles Rescue Cell Senescence Through Separable Microneedle Patches for Diabetic Wound Healing.
Animal Study on Diabetic Foot, Chronic Wound, published in Adv Sci (Weinh) (2025) — summary generated from the PubMed abstract.
- 2025
Adv Sci (Weinh) - Level DLaboratory StudyPubMed
Aging Adipose-Derived Mesenchymal Stem Cells, Cultured on a Native Young Extracellular Matrix, Are Protected From Senescence and Apoptosis Along With Increased Expression of HLA-DR and CD74 Associated With PI3K Signaling
Laboratory Study, published in Aging Cell (2025) — summary generated from the PubMed abstract.
- 2025
Aging Cell - Level CProspective StudyEurope PMC
Extracellular Vesicles in Infrapatellar Fat Pad from Osteoarthritis Patients Impair Cartilage Metabolism and Induce Senescence
Prospective Study on Knee Osteoarthritis, Osteoarthritis, published in Adv Sci (Weinh) (2024) — summary generated from the PubMed abstract.
- 2024
Adv Sci (Weinh)19 citations - Level DAnimal StudyPubMed
Mesenchymal stem cell-derived extracellular vesicles relieve endothelial cell senescence via recovering CTRP9 upon repressing miR-674-5p in atherosclerosis.
Animal Study, published in Regen Ther (2024) — summary generated from the PubMed abstract.
- 2024
Regen Ther7 citations - Level DAnimal StudyPubMed
Extracellular Vesicles Derived from H 2 O 2 -Stimulated Adipose-Derived Stem Cells Alleviate Senescence in Diabetic Bone Marrow Mesenchymal Stem Cells and Restore Their Osteogenic Capacity.
Animal Study on Systemic / IV, published in Drug Des Devel Ther (2024) — summary generated from the PubMed abstract.
- 2024
Drug Des Devel Ther6 citations - Level DNarrative ReviewEurope PMC
Role of Mesenchymal Stem/Stromal Cells (MSCs) and MSC-Derived Extracellular Vesicles (EVs) in Prevention of Telomere Length Shortening, Cellular Senescence, and Accelerated Biological Aging
Narrative Review, published in Bioengineering (Basel) (2024) — summary generated from the PubMed abstract.
- 2024
Bioengineering (Basel)9 citations - Level DNarrative ReviewEurope PMC
Cellular Senescence and Extracellular Vesicles in the Pathogenesis and Treatment of Obesity-A Narrative Review
Narrative Review on Type 2 Diabetes, published in Int J Mol Sci (2024) — summary generated from the PubMed abstract.
- 2024
Int J Mol Sci20 citations - Level DAnimal StudyPubMed
Anti-aging effect of extracellular vesicles from mesenchymal stromal cells on senescence-induced chondrocytes in osteoarthritis.
Animal Study on Osteoarthritis, published in Aging (Albany NY) (2024) — summary generated from the PubMed abstract.
- 2024
Aging (Albany NY)6 citations - Level DAnimal StudyPubMed
Adipose mesenchymal stem cell-derived extracellular vesicles regulate PINK1/parkin-mediated mitophagy to repair high glucose-induced dermal fibroblast senescence and promote wound healing in rats with diabetic foot ulcer
Animal Study on Diabetic Foot, Chronic Wound, published in Acta Diabetol (2024) — summary generated from the PubMed abstract.
- 2024
Acta Diabetol - Level DLaboratory StudyPubMed
EGCG inhibits the inflammation and senescence inducing properties of MDA-MB-231 triple-negative breast cancer (TNBC) cells-derived extracellular vesicles in human adipose-derived mesenchymal stem cells.
Laboratory Study, published in Cancer Cell Int (2023) — summary generated from the PubMed abstract.
- 2023
Cancer Cell Int11 citations - Level DAnimal StudyPubMed
Transmissible Endoplasmic Reticulum Stress Mediated by Extracellular Vesicles from Adipocyte Promoting the Senescence of Adipose-Derived Mesenchymal Stem Cells in Hypertrophic Obesity.
Animal Study on Type 2 Diabetes, Chronic Inflammation, published in Oxid Med Cell Longev (2022) — summary generated from the PubMed abstract.
- 2022
Oxid Med Cell Longev11 citations - Level DLaboratory StudyEurope PMC
The role of extracellular vesicle miRNAs and tRNAs in synovial fibroblast senescence
Laboratory Study on Osteoarthritis, published in Front Mol Biosci (2022) — summary generated from the PubMed abstract.
- 2022
Front Mol Biosci8 citations - Level DAnimal StudyEurope PMC
Chitosan hydrogel-loaded MSC-derived extracellular vesicles promote skin rejuvenation by ameliorating the senescence of dermal fibroblasts
Animal Study on Skin Aging, published in Stem Cell Res Ther (2021) — summary generated from the PubMed abstract.
- 2021
Stem Cell Res Ther66 citations - Level CProspective StudyPubMed
Metabolic syndrome increases senescence-associated micro-RNAs in extracellular vesicles derived from swine and human mesenchymal stem/stromal cells.
Prospective Study with a reported sample of 6 on Type 2 Diabetes, published in Cell Commun Signal (2020) — summary generated from the PubMed abstract.
- 2020
- n = 6
Cell Commun Signal - Level DLaboratory StudyPubMed
Autologous decellularized extracellular matrix protects against H 2 O 2 -induced senescence and aging in adipose-derived stem cells and stimulates proliferation in vitro .
Laboratory Study on Facial Rejuvenation, published in Biosci Rep (2019) — summary generated from the PubMed abstract.
- 2019
Biosci Rep6 citations - Level DLaboratory StudyPubMed
Extracellular Vesicles from Adipose-Derived Mesenchymal Stem Cells Downregulate Senescence Features in Osteoarthritic Osteoblasts.
Laboratory Study on Osteoarthritis, Chronic Inflammation, published in Oxid Med Cell Longev (2017) — summary generated from the PubMed abstract.
- 2017
Oxid Med Cell Longev125 citations
In-depth reviewed studies (full Thai translation)
Evidence system- Level ARandomized Controlled Trial
Cell-based versus corticosteroid injections for knee pain in osteoarthritis: a randomized phase 3 trial
A multicentre randomized trial in 480 knee osteoarthritis patients comparing SVF, BMAC and umbilical cord MSCs against corticosteroid injection. At 12 months no cell product outperformed the steroid control.
- 2023
- United States
- n = 480
- Level AMeta-analysis
Intra-articular Injection of Autologous Adipose-Derived Stem Cells or Stromal Vascular Fractions: Are They Effective for Patients With Knee Osteoarthritis? A Systematic Review With Meta-analysis of Randomized Controlled Trials
Pooled five RCTs comparing ADSC/SVF injection with placebo or hyaluronic acid, finding significant pain and function improvement at 6 and 12 months.
- 2023
- South Korea
- Level AMeta-analysis
Rapid-acting pain relief in knee osteoarthritis: autologous-cultured adipose-derived mesenchymal stem cells outperform stromal vascular fraction: a systematic review and meta-analysis
Analysed 31 studies with 1,406 patients: cultured ADMSCs reduced pain from month 3, whereas SVF reached significance only at 12 months.
- 2024
- South Korea
- n = 1406