Research database
SVF Research Library
Search 52,792 real PubMed studies on SVF and adipose-derived stem cells — 19 matching records.
19 results — page 1 of 1
- Level DAnimal StudyEurope PMC
Exosomes derived from TGF-β1-modified mesenchymal stem cells protect septic mice by inducing macrophage M2 polarization
Animal Study on Chronic Inflammation, published in Mol Biol Rep (2026) — summary generated from the PubMed abstract.
- 2026
Mol Biol Rep - Level DAnimal StudyPubMed
Melatonin-pretreated mesenchymal stem cell-derived exosomes alleviate cavernous fibrosis in a rat model of nerve injury-induced erectile dysfunction via miR-145-5p/TGF-β/Smad axis.
Animal Study, published in Stem Cell Res Ther (2025) — summary generated from the PubMed abstract.
- 2025
Stem Cell Res Ther6 citations - Level DAnimal StudyPubMed
Adipose-Derived Stem Cell Exosomes Promote Scar-Free Healing of Diabetic Wounds via miR-204-5p/TGF- β 1/Smad Pathway.
Animal Study on Diabetic Foot, Chronic Wound, Scar, published in Stem Cells Int (2025) — summary generated from the PubMed abstract.
- 2025
Stem Cells Int10 citations - Level DAnimal StudyPubMed
miR-574-3p and miR-125a-5p in Adipose-Derived Mesenchymal Stem Cell Exosomes Synergistically Target TGF-β1/SMAD2 Signaling Pathway for the Treatment of Androgenic Alopecia.
Animal Study on Chronic Wound, Hair Loss, published in J Invest Dermatol (2025) — summary generated from the PubMed abstract.
- 2025
J Invest Dermatol4 citations - Level DAnimal StudyPubMed
Adipose-derived stem cell exosomes alleviate TGF-β1-induced urethral stricture fibrosis by suppressing the TGF-β/Smad pathway and downstream PDGFR-β/RAS/ERK signaling.
Animal Study, published in J Cell Commun Signal (2025) — summary generated from the PubMed abstract.
- 2025
J Cell Commun Signal - Level DAnimal StudyPubMed
Exosomes from adipose-derived mesenchymal stem cell improve diabetic wound healing and inhibit fibrosis via miR-128-1-5p/TGF-β1/Smad axis.
Animal Study on Diabetic Foot, Chronic Wound, Scar, published in Mol Cell Endocrinol (2024) — summary generated from the PubMed abstract.
- 2024
Mol Cell Endocrinol - Level DLaboratory StudyPubMed
In vitro Chondrogenic Induction Promotes the Expression Level of IL-10 via the TGF-β/SMAD and Canonical Wnt/β-catenin Signaling Pathways in Exosomes Secreted by Human Adipose Tissue-derived Mesenchymal Stem Cells.
Laboratory Study on Cartilage Damage, published in Cell Biochem Biophys (2024) — summary generated from the PubMed abstract.
- 2024
Cell Biochem Biophys - Level DLaboratory StudyEurope PMC
Resveratrol reinforces the therapeutic effect of mesenchymal stem cell (MSC)-derived exosomes against renal ischemia‒reperfusion injury (RIRI)-associated fibrosis by suppressing TGF-β-induced epithelial-mesenchymal trans
Laboratory Study on Systemic / IV, published in Int J Cardiol Cardiovasc Risk Prev (2024) — summary generated from the PubMed abstract.
- 2024
Int J Cardiol Cardiovasc Risk Prev6 citations - Level DAnimal StudyPubMed
Adipose-derived stem cell exosomes attenuates myofibroblast transformation via inhibiting autophagy through TGF-β/Smad2 axis in oral submucosal fibrosis.
Animal Study, published in J Nanobiotechnology (2024) — summary generated from the PubMed abstract.
- 2024
J Nanobiotechnology5 citations - Level DLaboratory StudyPubMed
Adipose Mesenchymal Stromal Cell-Derived Exosomes Carrying MiR-122-5p Antagonize the Inhibitory Effect of Dihydrotestosterone on Hair Follicles by Targeting the TGF-β1/SMAD3 Signaling Pathway.
Laboratory Study on Hair Loss, published in Int J Mol Sci (2023) — summary generated from the PubMed abstract.
- 2023
Int J Mol Sci56 citations - Level DAnimal StudyEurope PMC
Amniotic fluid-derived exosomes attenuated fibrotic changes in POI rats through modulation of the TGF-β/Smads signaling pathway
Animal Study on Hair & Scalp, published in J Ovarian Res (2023) — summary generated from the PubMed abstract.
- 2023
J Ovarian Res31 citations - Level DAnimal StudyPubMed
Mechanism of exosomes from adipose-derived mesenchymal stem cells on sepsis-induced acute lung injury by promoting TGF-β secretion in macrophages.
Animal Study on Chronic Inflammation, published in Surgery (2023) — summary generated from the PubMed abstract.
- 2023
Surgery24 citations - Level DAnimal StudyPubMed
Exosomes from human adipose-derived mesenchymal stem cells attenuate localized scleroderma fibrosis by the let-7a-5p/TGF-βR1/Smad axis.
Animal Study, published in J Dermatol Sci (2023) — summary generated from the PubMed abstract.
- 2023
J Dermatol Sci7 citations - Level DAnimal StudyPubMed
Exosomes derived from mesenchymal stem cells primed with disease-condition-serum improved therapeutic efficacy in a mouse rheumatoid arthritis model via enhanced TGF-β1 production.
Animal Study with a reported sample of 10 on Immune Modulation, Autoimmune Research, published in Stem Cell Res Ther (2023) — summary generated from the PubMed abstract.
- 2023
- n = 10
Stem Cell Res Ther - Level CProspective StudyPubMed
Adipose-Derived Circulating Exosomes Promote Protection of the Pulmonary Endothelial Barrier by Inhibiting EndMT and Oxidative Stress through Down-Regulation of the TGF- β Pathway: A Potential Explanation for the Obesity
Prospective Study, published in Oxid Med Cell Longev (2022) — summary generated from the PubMed abstract.
- 2022
Oxid Med Cell Longev16 citations - Level DLaboratory StudyPubMed
The effect of inhibiting exosomes derived from adipose-derived stem cells via the TGF-β1/Smad pathway on the fibrosis of keloid fibroblasts.
Laboratory Study on Scar, published in Gland Surg (2021) — summary generated from the PubMed abstract.
- 2021
Gland Surg32 citations - Level DAnimal StudyPubMed
Exosomes from miR-29a-modified adipose-derived mesenchymal stem cells reduce excessive scar formation by inhibiting TGF-β2/Smad3 signaling.
Animal Study on Chronic Wound, Scar, published in Mol Med Rep (2021) — summary generated from the PubMed abstract.
- 2021
Mol Med Rep86 citations - Level DAnimal StudyEurope PMC
Human bone marrow mesenchymal stem cell-derived exosomes stimulate cutaneous wound healing mediates through TGF-β/Smad signaling pathway
Animal Study on Chronic Wound, published in Stem Cell Res Ther (2020) — summary generated from the PubMed abstract.
- 2020
Stem Cell Res Ther124 citations - Level CProspective StudyPubMed
Exosomes from Adipose-Derived Stem Cells Promotes VEGF-C-Dependent Lymphangiogenesis by Regulating miRNA-132/TGF-β Pathway.
Prospective Study, published in Cell Physiol Biochem (2018) — summary generated from the PubMed abstract.
- 2018
Cell Physiol Biochem63 citations
In-depth reviewed studies (full Thai translation)
Evidence system- Level ARandomized Controlled Trial
Cell-based versus corticosteroid injections for knee pain in osteoarthritis: a randomized phase 3 trial
A multicentre randomized trial in 480 knee osteoarthritis patients comparing SVF, BMAC and umbilical cord MSCs against corticosteroid injection. At 12 months no cell product outperformed the steroid control.
- 2023
- United States
- n = 480
- Level AMeta-analysis
Intra-articular Injection of Autologous Adipose-Derived Stem Cells or Stromal Vascular Fractions: Are They Effective for Patients With Knee Osteoarthritis? A Systematic Review With Meta-analysis of Randomized Controlled Trials
Pooled five RCTs comparing ADSC/SVF injection with placebo or hyaluronic acid, finding significant pain and function improvement at 6 and 12 months.
- 2023
- South Korea
- Level AMeta-analysis
Rapid-acting pain relief in knee osteoarthritis: autologous-cultured adipose-derived mesenchymal stem cells outperform stromal vascular fraction: a systematic review and meta-analysis
Analysed 31 studies with 1,406 patients: cultured ADMSCs reduced pain from month 3, whereas SVF reached significance only at 12 months.
- 2024
- South Korea
- n = 1406