Research database
SVF Research Library
Search 52,792 real PubMed studies on SVF and adipose-derived stem cells — 26 matching records.
26 results — page 1 of 2
- Level DAnimal StudyPubMed
Extracellular vesicles secreted by adipose-derived stem cells alleviate dedifferentiation and senescence in monolayer-expanded chondrocytes by suppressing interleukin-1β-induced MAPK signaling.
Animal Study on Cartilage Damage, published in Cell Transplant (2026) — summary generated from the PubMed abstract.
- 2026
Cell Transplant - Level DNarrative ReviewEurope PMC
Apoptotic mesenchymal stem cells and their secreted apoptotic extracellular vesicles: therapeutic applications and mechanisms
Narrative Review on Chronic Inflammation, Immune Modulation, published in Stem Cell Res Ther (2025) — summary generated from the PubMed abstract.
- 2025
Stem Cell Res Ther16 citations - Level DAnimal StudyEurope PMC
Extracellular vesicles secreted from mesenchymal stem cells ameliorate renal ischemia reperfusion injury by delivering miR-100-5p targeting FKBP5/AKT axis
Animal Study on Chronic Kidney Disease, Acute Kidney Injury, published in Sci Rep (2024) — summary generated from the PubMed abstract.
- 2024
Sci Rep10 citations - Level DAnimal StudyPubMed
Extracellular vesicles secreted by equine adipose mesenchymal stem cells preconditioned with transforming growth factor β-1 are enriched in anti-fibrotic miRNAs and inhibit the expression of fibrotic genes in an in vitro
Animal Study, published in Vet Q (2024) — summary generated from the PubMed abstract.
- 2024
Vet Q - Level DAnimal StudyEurope PMC
Improvement of androgenic alopecia by extracellular vesicles secreted from hyaluronic acid-stimulated induced mesenchymal stem cells
Animal Study on Hair Loss, Hair Regeneration, published in Stem Cell Res Ther (2024) — summary generated from the PubMed abstract.
- 2024
Stem Cell Res Ther13 citations - Level DAnimal StudyEurope PMC
Priming Mesenchymal Stem Cells with Lipopolysaccharide Boosts the Immunomodulatory and Regenerative Activity of Secreted Extracellular Vesicles
Animal Study with a reported sample of 8 on Chronic Inflammation, Immune Modulation, published in Pharmaceutics (2024) — summary generated from the PubMed abstract.
- 2024
- n = 8
Pharmaceutics9 citations - Level DLaboratory StudyEurope PMC
Engineering Extracellular Matrix-Bound Nanovesicles Secreted by Three-Dimensional Human Mesenchymal Stem Cells
Laboratory Study on Stroke Research, Chronic Inflammation, published in Adv Healthc Mater (2023) — summary generated from the PubMed abstract.
- 2023
Adv Healthc Mater11 citations - Level DAnimal StudyPubMed
Early Effects of Extracellular Vesicles Secreted by Adipose Tissue Mesenchymal Cells in Renal Ischemia Followed by Reperfusion: Mechanisms Rely on a Decrease in Mitochondrial Anion Superoxide Production.
Animal Study on Acute Kidney Injury, published in Int J Mol Sci (2022) — summary generated from the PubMed abstract.
- 2022
Int J Mol Sci - Level DLaboratory StudyEurope PMC
Unbiased proteomic analysis of extracellular vesicles secreted by senescent human vascular smooth muscle cells reveals their ability to modulate immune cell functions
Laboratory Study, published in Geroscience (2022) — summary generated from the PubMed abstract.
- 2022
Geroscience42 citations - Level DAnimal StudyPubMed
Adipose-derived mesenchymal stem cell-secreted extracellular vesicles alleviate non-alcoholic fatty liver disease via delivering miR-223-3p.
Animal Study, published in Adipocyte (2022) — summary generated from the PubMed abstract.
- 2022
Adipocyte48 citations - Level DLaboratory StudyPubMed
Mesenchymal Stem Cell Secreted-Extracellular Vesicles are Involved in Chondrocyte Production and Reduce Adipogenesis during Stem Cell Differentiation.
Laboratory Study on Cartilage Damage, published in Tissue Eng Regen Med (2022) — summary generated from the PubMed abstract.
- 2022
Tissue Eng Regen Med14 citations - Level BClinical TrialEurope PMC
Molecular Characterization of Secreted Factors and Extracellular Vesicles-Embedded miRNAs from Bone Marrow-Derived Mesenchymal Stromal Cells in Presence of Synovial Fluid from Osteoarthritis Patients
Clinical Trial on Osteoarthritis, Chronic Inflammation, published in Biology (Basel) (2022) — summary generated from the PubMed abstract.
- 2022
Biology (Basel)7 citations - Level CProspective StudyEurope PMC
Micro-RNAs Shuttled by Extracellular Vesicles Secreted from Mesenchymal Stem Cells Dampen Astrocyte Pathological Activation and Support Neuroprotection in In-Vitro Models of ALS
Prospective Study on Neuroinflammation, Chronic Inflammation, published in Cells (2022) — summary generated from the PubMed abstract.
- 2022
Cells33 citations - Level DAnimal StudyPubMed
Identification of Angiogenic Cargo in Extracellular Vesicles Secreted from Human Adipose Tissue-Derived Stem Cells and Induction of Angiogenesis In Vitro and In Vivo.
Animal Study, published in Pharmaceutics (2021) — summary generated from the PubMed abstract.
- 2021
Pharmaceutics33 citations - Level CProspective StudyPubMed
Cartilage Protective and Immunomodulatory Features of Osteoarthritis Synovial Fluid-Treated Adipose-Derived Mesenchymal Stem Cells Secreted Factors and Extracellular Vesicles-Embedded miRNAs.
Prospective Study on Osteoarthritis, Immune Modulation, published in Cells (2021) — summary generated from the PubMed abstract.
- 2021
Cells35 citations - Level DAnimal StudyEurope PMC
High fructose exposure modifies the amount of adipocyte-secreted microRNAs into extracellular vesicles in supernatants and plasma
Animal Study, published in PeerJ (2021) — summary generated from the PubMed abstract.
- 2021
PeerJ1 citations - Level DAnimal StudyPubMed
microRNA-26a shuttled by extracellular vesicles secreted from adipose-derived mesenchymal stem cells reduce neuronal damage through KLF9-mediated regulation of TRAF2/KLF2 axis.
Animal Study, published in Adipocyte (2021) — summary generated from the PubMed abstract.
- 2021
Adipocyte16 citations - Level DAnimal StudyPubMed
The Role of Extracellular Vesicles Secreted From Thermal Stress-Induced Adipose-Derived Stem Cells on Bone Regeneration.
Animal Study, published in J Craniofac Surg (2021) — summary generated from the PubMed abstract.
- 2021
J Craniofac Surg3 citations - Level DLaboratory StudyEurope PMC
Biomaterials functionalized with MSC secreted extracellular vesicles and soluble factors for tissue regeneration
Laboratory Study on Immune Modulation, published in Adv Funct Mater (2020) — summary generated from the PubMed abstract.
- 2020
Adv Funct Mater296 citations - Level DLaboratory StudyPubMed
MiRNA Profiles of Extracellular Vesicles Secreted by Mesenchymal Stromal Cells-Can They Predict Potential Off-Target Effects?
Laboratory Study, published in Biomolecules (2020) — summary generated from the PubMed abstract.
- 2020
Biomolecules29 citations - Level DLaboratory StudyEurope PMC
The influence of secreted factors and extracellular vesicles in ovarian cancer metastasis
Laboratory Study, published in EJC Suppl (2020) — summary generated from the PubMed abstract.
- 2020
EJC Suppl12 citations - Level DAnimal StudyPubMed
Adipose mesenchymal stem cells-secreted extracellular vesicles containing microRNA-192 delays diabetic retinopathy by targeting ITGA1.
Animal Study on Chronic Inflammation, published in J Cell Physiol (2020) — summary generated from the PubMed abstract.
- 2020
J Cell Physiol - Level DAnimal StudyPubMed
Extracellular vesicles-derived miR-150-5p secreted by adipose-derived mesenchymal stem cells inhibits CXCL1 expression to attenuate hepatic fibrosis.
Animal Study on Hip, published in J Cell Mol Med (2020) — summary generated from the PubMed abstract.
- 2020
J Cell Mol Med57 citations - Level DAnimal StudyPubMed
Extracellular Vesicles Secreted by Human Adipose-derived Stem Cells (hASCs) Improve Survival Rate of Rats with Acute Liver Failure by Releasing lncRNA H19.
Animal Study, published in EBioMedicine (2018) — summary generated from the PubMed abstract.
- 2018
EBioMedicine53 citations
In-depth reviewed studies (full Thai translation)
Evidence system- Level ARandomized Controlled Trial
Cell-based versus corticosteroid injections for knee pain in osteoarthritis: a randomized phase 3 trial
A multicentre randomized trial in 480 knee osteoarthritis patients comparing SVF, BMAC and umbilical cord MSCs against corticosteroid injection. At 12 months no cell product outperformed the steroid control.
- 2023
- United States
- n = 480
- Level AMeta-analysis
Intra-articular Injection of Autologous Adipose-Derived Stem Cells or Stromal Vascular Fractions: Are They Effective for Patients With Knee Osteoarthritis? A Systematic Review With Meta-analysis of Randomized Controlled Trials
Pooled five RCTs comparing ADSC/SVF injection with placebo or hyaluronic acid, finding significant pain and function improvement at 6 and 12 months.
- 2023
- South Korea
- Level AMeta-analysis
Rapid-acting pain relief in knee osteoarthritis: autologous-cultured adipose-derived mesenchymal stem cells outperform stromal vascular fraction: a systematic review and meta-analysis
Analysed 31 studies with 1,406 patients: cultured ADMSCs reduced pain from month 3, whereas SVF reached significance only at 12 months.
- 2024
- South Korea
- n = 1406