Research database
SVF Research Library
Search 52,792 real PubMed studies on SVF and adipose-derived stem cells — 34 matching records.
34 results — page 1 of 2
- Level CCase Report / SeriesPubMed
Adipose-derived stromal vascular fraction injection for radiation-induced bladder fibrosis: a first-in-human pilot study.
Case Report / Series, published in Stem Cells Transl Med (2026) — summary generated from the PubMed abstract.
- 2026
Stem Cells Transl Med - Level DNarrative ReviewPubMed
Exosomes derived from human adipose mesenchymal stem cells act as a therapeutic target for oral submucous fibrosis.
Narrative Review, published in J Stomatol Oral Maxillofac Surg (2025) — summary generated from the PubMed abstract.
- 2025
J Stomatol Oral Maxillofac Surg - Level CProspective StudyPubMed
Charge-reversed small extracellular vesicles from human adipose-derived mesenchymal stromal cells attenuate renal fibrosis postacute kidney injury by inhibiting epithelial-mesenchymal transition progression in SD rat mod
Prospective Study on Chronic Kidney Disease, Acute Kidney Injury, published in Cytotherapy (2025) — summary generated from the PubMed abstract.
- 2025
Cytotherapy - Level DAnimal StudyPubMed
Effectiveness of human adipose tissue-derived mesenchymal stem cells expressing alpha-1 antitrypsin gene in liver fibrosis: a study in mice.
Animal Study on Chronic Inflammation, published in Gastroenterol Hepatol Bed Bench (2024) — summary generated from the PubMed abstract.
- 2024
Gastroenterol Hepatol Bed Bench - Level DAnimal StudyPubMed
Meflin/ISLR is a marker of adipose stem and progenitor cells in mice and humans that suppresses white adipose tissue remodeling and fibrosis.
Animal Study on Type 2 Diabetes, published in Genes Cells (2024) — summary generated from the PubMed abstract.
- 2024
Genes Cells4 citations - Level DAnimal StudyPubMed
Comprehensive evaluation of the mechanism of human adipose mesenchymal stem cells ameliorating liver fibrosis by transcriptomics and metabolomics analysis.
Animal Study on Chronic Wound, published in Sci Rep (2024) — summary generated from the PubMed abstract.
- 2024
Sci Rep4 citations - Level DAnimal StudyPubMed
Human adipose mesenchymal stem cell-derived exosomes alleviate fibrosis by restraining ferroptosis in keloids.
Animal Study on Scar, published in Front Pharmacol (2024) — summary generated from the PubMed abstract.
- 2024
Front Pharmacol4 citations - Level DAnimal StudyPubMed
Exosomes derived from human adipose mesenchymal stem cells ameliorate hepatic fibrosis by inhibiting PI3K/Akt/mTOR pathway and remodeling choline metabolism.
Animal Study on Chronic Wound, published in J Nanobiotechnology (2023) — summary generated from the PubMed abstract.
- 2023
J Nanobiotechnology - Level DAnimal StudyPubMed
Reversal of Pulmonary Fibrosis: Human Umbilical Mesenchymal Stem Cells from Wharton's Jelly versus Human-Adipose-Derived Mesenchymal Stem Cells.
Animal Study, published in Int J Mol Sci (2023) — summary generated from the PubMed abstract.
- 2023
Int J Mol Sci11 citations - Level DLaboratory StudyPubMed
Human adipose ECM alleviates radiation-induced skin fibrosis via endothelial cell-mediated M2 macrophage polarization.
Laboratory Study on Chronic Inflammation, published in iScience (2023) — summary generated from the PubMed abstract.
- 2023
iScience8 citations - Level DAnimal StudyPubMed
Exosomes from human adipose-derived mesenchymal stem cells attenuate localized scleroderma fibrosis by the let-7a-5p/TGF-βR1/Smad axis.
Animal Study, published in J Dermatol Sci (2023) — summary generated from the PubMed abstract.
- 2023
J Dermatol Sci7 citations - Level DLaboratory StudyPubMed
Exosomes Derived from Human Adipose Mesenchymal Stem Cells Inhibits Fibrosis and Treats Oral Submucous Fibrosis via the miR-181a-5p/Smad2 Axis.
Laboratory Study, published in Tissue Eng Regen Med (2023) — summary generated from the PubMed abstract.
- 2023
Tissue Eng Regen Med - Level DAnimal StudyPubMed
Role of human adipose-derived stem cells (hADSC) on TGF-β1, type I collagen, and fibrosis degree in bladder obstruction model of Wistar rats.
Animal Study, published in BMC Urol (2022) — summary generated from the PubMed abstract.
- 2022
BMC Urol5 citations - Level DAnimal StudyPubMed
Therapeutic efficacy of human adipose mesenchymal stem cells in Crohn's colon fibrosis is improved by IFN-γ and kynurenic acid priming through indoleamine 2,3-dioxygenase-1 signaling.
Animal Study on Autoimmune Research, published in Stem Cell Res Ther (2022) — summary generated from the PubMed abstract.
- 2022
Stem Cell Res Ther - Level DAnimal StudyPubMed
Surgical implantation of human adipose derived stem cells attenuates experimentally induced hepatic fibrosis in rats.
Animal Study, published in Mol Med (2022) — summary generated from the PubMed abstract.
- 2022
Mol Med5 citations - Level CProspective StudyPubMed
Exosomes derived from human adipose mesenchymal stem cells attenuate hypertrophic scar fibrosis by miR-192-5p/IL-17RA/Smad axis.
Prospective Study on Chronic Wound, Scar, published in Stem Cell Res Ther (2021) — summary generated from the PubMed abstract.
- 2021
Stem Cell Res Ther - Level DAnimal StudyPubMed
Conditioned medium from a human adipose-derived stem cell line ameliorates inflammation and fibrosis in a lung experimental model of idiopathic pulmonary fibrosis.
Animal Study, published in Life Sci (2021) — summary generated from the PubMed abstract.
- 2021
Life Sci12 citations - Level CProspective StudyPubMed
Hepatocyte Growth Factor Secreted from Human Adipose-Derived Stem Cells Inhibits Fibrosis in Hypertrophic Scar Fibroblasts.
Prospective Study on Chronic Wound, Scar, published in Curr Mol Med (2020) — summary generated from the PubMed abstract.
- 2020
Curr Mol Med20 citations - Level DLaboratory StudyPubMed
Human adipose stem cell-derived extracellular nanovesicles for treatment of chronic liver fibrosis.
Laboratory Study on Chronic Wound, published in J Control Release (2020) — summary generated from the PubMed abstract.
- 2020
J Control Release46 citations - Level DAnimal StudyPubMed
Exosomes derived from GDNF-modified human adipose mesenchymal stem cells ameliorate peritubular capillary loss in tubulointerstitial fibrosis by activating the SIRT1/eNOS signaling pathway.
Animal Study on Chronic Kidney Disease, published in Theranostics (2020) — summary generated from the PubMed abstract.
- 2020
Theranostics106 citations - Level DAnimal StudyPubMed
GDNF enhances the anti-inflammatory effect of human adipose-derived mesenchymal stem cell-based therapy in renal interstitial fibrosis.
Animal Study on Chronic Kidney Disease, Chronic Inflammation, published in Stem Cell Res (2019) — summary generated from the PubMed abstract.
- 2019
Stem Cell Res29 citations - Level DLaboratory StudyPubMed
Impaired Glucocorticoid Suppression of TGFβ Signaling in Human Omental Adipose Tissues Limits Adipogenesis and May Promote Fibrosis.
Laboratory Study on Type 2 Diabetes, published in Diabetes (2018) — summary generated from the PubMed abstract.
- 2018
Diabetes21 citations - Level DLaboratory StudyPubMed
Human adipose tissue-derived stem cells inhibit the activity of keloid fibroblasts and fibrosis in a keloid model by paracrine signaling.
Laboratory Study on Burns, Scar, published in Burns (2017) — summary generated from the PubMed abstract.
- 2017
Burns47 citations - Level DAnimal StudyPubMed
Human adipose derived stem cells regress fibrosis in a chronic renal fibrotic model induced by adenine.
Animal Study on Chronic Kidney Disease, published in PLoS One (2017) — summary generated from the PubMed abstract.
- 2017
PLoS One18 citations
In-depth reviewed studies (full Thai translation)
Evidence system- Level ARandomized Controlled Trial
Cell-based versus corticosteroid injections for knee pain in osteoarthritis: a randomized phase 3 trial
A multicentre randomized trial in 480 knee osteoarthritis patients comparing SVF, BMAC and umbilical cord MSCs against corticosteroid injection. At 12 months no cell product outperformed the steroid control.
- 2023
- United States
- n = 480
- Level AMeta-analysis
Intra-articular Injection of Autologous Adipose-Derived Stem Cells or Stromal Vascular Fractions: Are They Effective for Patients With Knee Osteoarthritis? A Systematic Review With Meta-analysis of Randomized Controlled Trials
Pooled five RCTs comparing ADSC/SVF injection with placebo or hyaluronic acid, finding significant pain and function improvement at 6 and 12 months.
- 2023
- South Korea
- Level AMeta-analysis
Rapid-acting pain relief in knee osteoarthritis: autologous-cultured adipose-derived mesenchymal stem cells outperform stromal vascular fraction: a systematic review and meta-analysis
Analysed 31 studies with 1,406 patients: cultured ADMSCs reduced pain from month 3, whereas SVF reached significance only at 12 months.
- 2024
- South Korea
- n = 1406