Research database
SVF Research Library
Search 52,792 real PubMed studies on SVF and adipose-derived stem cells — 91 matching records.
91 results — page 1 of 4
- Level DLaboratory StudyPubMed
PPARγ antagonists induce aromatase transcription in adipose tissue cultures.
Laboratory Study, published in Biochem Pharmacol (2024) — summary generated from the PubMed abstract.
- 2024
Biochem Pharmacol - Level DLaboratory StudyEurope PMC
Effects of ethanol or ethylene glycol exposure on PPARγ and aromatase expression in adipose tissue
Laboratory Study, published in Biochem Biophys Rep (2024) — summary generated from the PubMed abstract.
- 2024
Biochem Biophys Rep - Level CProspective StudyEurope PMC
Type I IFN stimulates IFI16-mediated aromatase expression in adipocytes that promotes E 2 -dependent growth of ER-positive breast cancer
Prospective Study on Face & Skin, published in Cell Mol Life Sci (2022) — summary generated from the PubMed abstract.
- 2022
Cell Mol Life Sci14 citations - Level DNarrative ReviewEurope PMC
Exosomes and Biomaterials: In Search of a New Therapeutic Strategy for Multiple Sclerosis
Narrative Review on Neuroinflammation, Immune Modulation, published in Life (Basel) (2022) — summary generated from the PubMed abstract.
- 2022
Life (Basel)16 citations - Level DAnimal StudyPubMed
CC chemokine ligand 2 (CCL2) stimulates aromatase gene expression in mammary adipose tissue.
Animal Study, published in FASEB J (2021) — summary generated from the PubMed abstract.
- 2021
FASEB J - Level DAnimal StudyPubMed
Identification of PARP-1, Histone H1 and SIRT-1 as New Regulators of Breast Cancer-Related Aromatase Promoter I.3/II.
Animal Study, published in Cells (2020) — summary generated from the PubMed abstract.
- 2020
Cells - Level DNarrative ReviewEurope PMC
Particles Containing Cells as a Strategy to Promote Remyelination in Patients With Multiple Sclerosis
Narrative Review on Neuroinflammation, Autoimmune Research, published in Front Neurol (2020) — summary generated from the PubMed abstract.
- 2020
Front Neurol11 citations - Level CProspective StudyPubMed
Mammary adipose stromal cells derived from obese women reduce sensitivity to the aromatase inhibitor anastrazole in an organotypic breast model.
Prospective Study, published in FASEB J (2019) — summary generated from the PubMed abstract.
- 2019
FASEB J23 citations - Level DAnimal StudyPubMed
IL-10 suppresses TNF-α-induced expression of human aromatase gene in mammary adipose tissue.
Animal Study on Chronic Inflammation, published in FASEB J (2018) — summary generated from the PubMed abstract.
- 2018
FASEB J - Level CProspective StudyEurope PMC
Metformin inhibits stromal aromatase expression and tumor progression in a rodent model of postmenopausal breast cancer
Prospective Study on Type 2 Diabetes, published in Breast Cancer Res (2018) — summary generated from the PubMed abstract.
- 2018
Breast Cancer Res44 citations - Level DLaboratory StudyPubMed
Prostaglandin E 2 down-regulates sirtuin 1 (SIRT1), leading to elevated levels of aromatase, providing insights into the obesity-breast cancer connection.
Laboratory Study, published in J Biol Chem (2018) — summary generated from the PubMed abstract.
- 2018
J Biol Chem - Level BRandomized Controlled TrialPubMed
Umbilical Cord-Derived Mesenchymal Stromal Cells (MSCs) for Knee Osteoarthritis: Repeated MSC Dosing Is Superior to a Single MSC Dose and to Hyaluronic Acid in a Controlled Randomized Phase I/II Trial.
Randomized Controlled Trial with a reported sample of 8 on Knee Osteoarthritis, Osteoarthritis, published in Stem Cells Transl Med (2018) — summary generated from the PubMed abstract.
- 2018
- n = 8
Stem Cells Transl Med - Level DAnimal StudyPubMed
Leptin regulation of the p53-HIF1α/PKM2-aromatase axis in breast adipose stromal cells: a novel mechanism for the obesity-breast cancer link.
Animal Study, published in Int J Obes (Lond) (2017) — summary generated from the PubMed abstract.
- 2017
Int J Obes (Lond) - Level CProspective StudyPubMed
Des-acyl ghrelin inhibits the capacity of macrophages to stimulate the expression of aromatase in breast adipose stromal cells.
Prospective Study on Chronic Inflammation, published in J Steroid Biochem Mol Biol (2016) — summary generated from the PubMed abstract.
- 2016
J Steroid Biochem Mol Biol - Level CProspective StudyPubMed
Hsp90 and PKM2 Drive the Expression of Aromatase in Li-Fraumeni Syndrome Breast Adipose Stromal Cells.
Prospective Study, published in J Biol Chem (2016) — summary generated from the PubMed abstract.
- 2016
J Biol Chem - Level DNarrative ReviewPubMed
Inflammation, dysregulated metabolism and aromatase in obesity and breast cancer.
Narrative Review, published in Curr Opin Pharmacol (2016) — summary generated from the PubMed abstract.
- 2016
Curr Opin Pharmacol - Level CProspective StudyPubMed
[Effect of free fatty acids on CYP19A1 (aromatase) gene expression in human adipose tissue stromal vascular fraction cells].
Prospective Study with a reported sample of 38, published in Przegl Lek (2016) — summary generated from the PubMed abstract.
- 2016
- n = 38
Przegl Lek - Level CProspective StudyPubMed
Prostaglandin E2 inhibits p53 in human breast adipose stromal cells: a novel mechanism for the regulation of aromatase in obesity and breast cancer.
Prospective Study, published in Cancer Res (2015) — summary generated from the PubMed abstract.
- 2015
Cancer Res - Level DAnimal StudyPubMed
Aromatase expression increases the survival and malignancy of estrogen receptor positive breast cancer cells.
Animal Study on Systemic / IV, published in PLoS One (2015) — summary generated from the PubMed abstract.
- 2015
PLoS One - Level DLaboratory StudyPubMed
Collagen and prostaglandin E₂ regulate aromatase expression through the PI3K/AKT/IKK and the MAP kinase pathways in adipose stromal cells.
Laboratory Study, published in Mol Med Rep (2015) — summary generated from the PubMed abstract.
- 2015
Mol Med Rep - Level DNarrative ReviewPubMed
Aromatase overexpression in dysfunctional adipose tissue links obesity to postmenopausal breast cancer.
Narrative Review on Hip, published in J Steroid Biochem Mol Biol (2015) — summary generated from the PubMed abstract.
- 2015
J Steroid Biochem Mol Biol - Level DLaboratory StudyPubMed
Ghrelin and des-acyl ghrelin inhibit aromatase expression and activity in human adipose stromal cells: suppression of cAMP as a possible mechanism.
Laboratory Study, published in Breast Cancer Res Treat (2014) — summary generated from the PubMed abstract.
- 2014
Breast Cancer Res Treat - Level DLaboratory StudyPubMed
Melatonin modulates aromatase activity and expression in endothelial cells.
Laboratory Study, published in Oncol Rep (2013) — summary generated from the PubMed abstract.
- 2013
Oncol Rep - Level CProspective StudyPubMed
HIF-1α stimulates aromatase expression driven by prostaglandin E2 in breast adipose stroma.
Prospective Study on Hip, published in Breast Cancer Res (2013) — summary generated from the PubMed abstract.
- 2013
Breast Cancer Res
In-depth reviewed studies (full Thai translation)
Evidence system- Level ARandomized Controlled Trial
Cell-based versus corticosteroid injections for knee pain in osteoarthritis: a randomized phase 3 trial
A multicentre randomized trial in 480 knee osteoarthritis patients comparing SVF, BMAC and umbilical cord MSCs against corticosteroid injection. At 12 months no cell product outperformed the steroid control.
- 2023
- United States
- n = 480
- Level AMeta-analysis
Intra-articular Injection of Autologous Adipose-Derived Stem Cells or Stromal Vascular Fractions: Are They Effective for Patients With Knee Osteoarthritis? A Systematic Review With Meta-analysis of Randomized Controlled Trials
Pooled five RCTs comparing ADSC/SVF injection with placebo or hyaluronic acid, finding significant pain and function improvement at 6 and 12 months.
- 2023
- South Korea
- Level AMeta-analysis
Rapid-acting pain relief in knee osteoarthritis: autologous-cultured adipose-derived mesenchymal stem cells outperform stromal vascular fraction: a systematic review and meta-analysis
Analysed 31 studies with 1,406 patients: cultured ADMSCs reduced pain from month 3, whereas SVF reached significance only at 12 months.
- 2024
- South Korea
- n = 1406