Research database
SVF Research Library
Search 52,792 real PubMed studies on SVF and adipose-derived stem cells — 25 matching records.
25 results — page 1 of 2
- Level DAnimal StudyPubMed
Mesenchymal stromal cell therapy is a long-term regenerative approach for chronic radiation cystitis, involving coordinated modulation of the urothelial, immune, vascular, and fibrotic pathways.
Animal Study on Face & Skin, Systemic / IV, published in Stem Cell Res Ther (2026) — summary generated from the PubMed abstract.
- 2026
Stem Cell Res Ther - Level AMeta-analysisPubMed
Antifibrotic efficacy of adipose-derived mesenchymal stem cell-based therapeutic strategies in pre-clinical models of pulmonary fibrosis: A systematic review and meta-analysis.
Meta-analysis on Scar, published in Eur J Pharmacol (2026) — summary generated from the PubMed abstract.
- 2026
Eur J Pharmacol - Level DAnimal StudyPubMed
Short preconditioning with TGFβ of equine adipose tissue-derived mesenchymal stem cells predisposes towards an anti-fibrotic secretory phenotype: A possible tool for treatment of endometrosis in mares.
Animal Study on Chronic Inflammation, published in Theriogenology (2024) — summary generated from the PubMed abstract.
- 2024
Theriogenology - Level DAnimal StudyPubMed
Extracellular vesicles secreted by equine adipose mesenchymal stem cells preconditioned with transforming growth factor β-1 are enriched in anti-fibrotic miRNAs and inhibit the expression of fibrotic genes in an in vitro
Animal Study, published in Vet Q (2024) — summary generated from the PubMed abstract.
- 2024
Vet Q - Level DLaboratory StudyPubMed
Cytokine priming enhances the antifibrotic effects of human adipose derived mesenchymal stromal cells conditioned medium.
Laboratory Study on Scar, published in Stem Cell Res Ther (2024) — summary generated from the PubMed abstract.
- 2024
Stem Cell Res Ther8 citations - Level CProspective StudyPubMed
Adipose-Derived Mesenchymal Stem Cells (ADSCs) Have Anti-Fibrotic Effects on Lung Fibroblasts from Idiopathic Pulmonary Fibrosis (IPF) Patients.
Prospective Study, published in Cells (2024) — summary generated from the PubMed abstract.
- 2024
Cells3 citations - Level DAnimal StudyPubMed
Conditioned Medium from Human Amniotic Membrane-Derived Mesenchymal Stem Cells Modulates Inflammatory and Myofibrotic Factors in Vivo.
Animal Study on Cardiovascular Disease, published in J Tehran Heart Cent (2024) — summary generated from the PubMed abstract.
- 2024
J Tehran Heart Cent1 citations - Level BClinical TrialEurope PMC
Mesenchymal stem cells in fibrotic diseases-the two sides of the same coin
Clinical Trial, published in Acta Pharmacol Sin (2023) — summary generated from the PubMed abstract.
- 2023
Acta Pharmacol Sin80 citations - Level BClinical TrialEurope PMC
Potential angiogenic, immunomodulatory, and antifibrotic effects of mesenchymal stem cell-derived extracellular vesicles in systemic sclerosis
Clinical Trial on Immune Modulation, Autoimmune Research, published in Front Immunol (2023) — summary generated from the PubMed abstract.
- 2023
Front Immunol16 citations - Level DNarrative ReviewEurope PMC
Mesenchymal stem cell-based therapy for autoimmune-related fibrotic skin diseases-systemic sclerosis and sclerodermatous graft-versus-host disease
Narrative Review on Immune Modulation, Autoimmune Research, published in Stem Cell Res Ther (2023) — summary generated from the PubMed abstract.
- 2023
Stem Cell Res Ther16 citations - Level DLaboratory StudyPubMed
Anti-Inflammatory and Anti-Fibrotic Effect of Immortalized Mesenchymal-Stem-Cell-Derived Conditioned Medium on Human Lung Myofibroblasts and Epithelial Cells.
Laboratory Study on Chronic Inflammation, published in Int J Mol Sci (2022) — summary generated from the PubMed abstract.
- 2022
Int J Mol Sci8 citations - Level DLaboratory StudyPubMed
Antifibrotic TSG-6 Expression Is Synergistically Increased in Both Cells during Coculture of Mesenchymal Stem Cells and Macrophages via the JAK/STAT Signaling Pathway.
Laboratory Study, published in Int J Mol Sci (2022) — summary generated from the PubMed abstract.
- 2022
Int J Mol Sci17 citations - Level DAnimal StudyPubMed
Three-dimensional Differentiated Human Mesenchymal Stem Cells Exhibit Robust Antifibrotic Potential and Ameliorates Mouse Liver Fibrosis.
Animal Study, published in Cell Transplant (2021) — summary generated from the PubMed abstract.
- 2021
Cell Transplant - Level CProspective StudyPubMed
Extracellular Vesicles Are More Potent Than Adipose Mesenchymal Stromal Cells to Exert an Anti-Fibrotic Effect in an In Vitro Model of Systemic Sclerosis.
Prospective Study on Systemic / IV, published in Int J Mol Sci (2021) — summary generated from the PubMed abstract.
- 2021
Int J Mol Sci - Level BClinical TrialPubMed
Mesenchymal Stem Cells Therapies on Fibrotic Heart Diseases.
Clinical Trial on Cardiovascular Disease, published in Int J Mol Sci (2021) — summary generated from the PubMed abstract.
- 2021
Int J Mol Sci - Level BClinical TrialEurope PMC
Mesenchymal stem cell-derived extracellular vesicles in therapy against fibrotic diseases
Clinical Trial on Systemic / IV, published in Stem Cell Res Ther (2021) — summary generated from the PubMed abstract.
- 2021
Stem Cell Res Ther33 citations - Level DAnimal StudyPubMed
Anti-fibrotic effect of adipose-derived mesenchymal stem cell conditioned medium in muscle fibrosis.
Animal Study, published in Eur Rev Med Pharmacol Sci (2021) — summary generated from the PubMed abstract.
- 2021
Eur Rev Med Pharmacol Sci - Level CProspective StudyEurope PMC
Secreted matrix metalloproteinase-14 is a predictor for antifibrotic effect of IC-2-engineered mesenchymal stem cell sheets on liver fibrosis in mice
Prospective Study, published in Regen Ther (2021) — summary generated from the PubMed abstract.
- 2021
Regen Ther4 citations - Level DAnimal StudyPubMed
Comparative Evaluation of Anti-Fibrotic Effect of Tissue Specific Mesenchymal Stem Cells Derived Extracellular Vesicles for the Amelioration of CCl4 Induced Chronic Liver Injury.
Animal Study on Chronic Inflammation, published in Stem Cell Rev Rep (2021) — summary generated from the PubMed abstract.
- 2021
Stem Cell Rev Rep - Level DNarrative ReviewPubMed
Application of Mesenchymal Stem Cells in Inflammatory and Fibrotic Diseases.
Narrative Review on Immune Modulation, published in Int J Mol Sci (2020) — summary generated from the PubMed abstract.
- 2020
Int J Mol Sci - Level CProspective StudyPubMed
Mesenchymal stem cells of Systemic Sclerosis patients, derived from different sources, show a profibrotic microRNA profiling.
Prospective Study on Systemic / IV, published in Sci Rep (2019) — summary generated from the PubMed abstract.
- 2019
Sci Rep18 citations - Level DAnimal StudyPubMed
Mesenchymal stem cells have antifibrotic effects on transforming growth factor-β1-stimulated vocal fold fibroblasts.
Animal Study on Scar, published in Laryngoscope (2016) — summary generated from the PubMed abstract.
- 2016
Laryngoscope45 citations - Level DAnimal StudyEurope PMC
Antifibrotic Activity of Human Placental Amnion Membrane-Derived CD34+ Mesenchymal Stem/Progenitor Cell Transplantation in Mice With Thioacetamide-Induced Liver Injury
Animal Study on Face & Skin, published in Stem Cells Transl Med (2016) — summary generated from the PubMed abstract.
- 2016
Stem Cells Transl Med31 citations - Level CProspective StudyPubMed
The anti-fibrotic effects of mesenchymal stem cells on irradiated lungs via stimulating endogenous secretion of HGF and PGE2.
Prospective Study, published in Sci Rep (2015) — summary generated from the PubMed abstract.
- 2015
Sci Rep
In-depth reviewed studies (full Thai translation)
Evidence system- Level ARandomized Controlled Trial
Cell-based versus corticosteroid injections for knee pain in osteoarthritis: a randomized phase 3 trial
A multicentre randomized trial in 480 knee osteoarthritis patients comparing SVF, BMAC and umbilical cord MSCs against corticosteroid injection. At 12 months no cell product outperformed the steroid control.
- 2023
- United States
- n = 480
- Level AMeta-analysis
Intra-articular Injection of Autologous Adipose-Derived Stem Cells or Stromal Vascular Fractions: Are They Effective for Patients With Knee Osteoarthritis? A Systematic Review With Meta-analysis of Randomized Controlled Trials
Pooled five RCTs comparing ADSC/SVF injection with placebo or hyaluronic acid, finding significant pain and function improvement at 6 and 12 months.
- 2023
- South Korea
- Level AMeta-analysis
Rapid-acting pain relief in knee osteoarthritis: autologous-cultured adipose-derived mesenchymal stem cells outperform stromal vascular fraction: a systematic review and meta-analysis
Analysed 31 studies with 1,406 patients: cultured ADMSCs reduced pain from month 3, whereas SVF reached significance only at 12 months.
- 2024
- South Korea
- n = 1406