Research database
SVF Research Library
Search 52,792 real PubMed studies on SVF and adipose-derived stem cells — 39 matching records.
39 results — page 1 of 2
- Level DAnimal StudyPubMed
SOD2 promotes the immunosuppressive function of mesenchymal stem cells at the expense of adipocyte differentiation.
Animal Study on Immune Modulation, published in Mol Ther (2024) — summary generated from the PubMed abstract.
- 2024
Mol Ther28 citations - Level DAnimal StudyPubMed
Timing of Mesenchymal Stromal Cell Therapy Defines its Immunosuppressive Effects in a Rat Lung Transplantation Model.
Animal Study on Systemic / IV, published in Cell Transplant (2023) — summary generated from the PubMed abstract.
- 2023
Cell Transplant2 citations - Level CProspective StudyPubMed
Addressing the impact of high glucose microenvironment on the immunosuppressive characteristics of human mesenchymal stem cells.
Prospective Study on Immune Modulation, published in IUBMB Life (2023) — summary generated from the PubMed abstract.
- 2023
IUBMB Life - Level BClinical TrialEurope PMC
Mesenchymal stem cells transfer mitochondria to allogeneic Tregs in an HLA-dependent manner improving their immunosuppressive activity
Clinical Trial, published in Nat Commun (2022) — summary generated from the PubMed abstract.
- 2022
Nat Commun64 citations - Level DAnimal StudyPubMed
Influence of exposure to microbial ligands, immunosuppressive drugs and chronic kidney disease on endogenous immunomodulatory gene expression in feline adipose-derived mesenchymal stem cells.
Animal Study with a reported sample of 6 on Chronic Kidney Disease, Immune Modulation, published in J Feline Med Surg (2022) — summary generated from the PubMed abstract.
- 2022
- n = 6
J Feline Med Surg - Level CProspective StudyPubMed
Effect of Crohn's disease mesenteric mesenchymal stem cells and their extracellular vesicles on T-cell immunosuppressive capacity.
Prospective Study on Immune Modulation, Autoimmune Research, published in J Cell Mol Med (2022) — summary generated from the PubMed abstract.
- 2022
J Cell Mol Med - Level DAnimal StudyPubMed
Hypoxic preconditioning promotes the immunosuppressive effects of mesenchymal stem cells in mice with colitis.
Animal Study on Autoimmune Research, published in Res Vet Sci (2021) — summary generated from the PubMed abstract.
- 2021
Res Vet Sci - Level DAnimal StudyPubMed
The immunosuppressive mechanisms of mesenchymal stem cells are differentially regulated by platelet poor plasma and fetal bovine serum supplemented media.
Animal Study on Immune Modulation, published in Int Immunopharmacol (2020) — summary generated from the PubMed abstract.
- 2020
Int Immunopharmacol - Level DAnimal StudyEurope PMC
Immunosuppressive properties of cytochalasin B-induced membrane vesicles of mesenchymal stem cells: comparing with extracellular vesicles derived from mesenchymal stem cells
Animal Study on Immune Modulation, published in Sci Rep (2020) — summary generated from the PubMed abstract.
- 2020
Sci Rep35 citations - Level BClinical TrialPubMed
Umbilical Cord-Derived Mesenchymal Stem Cells Are Able to Use bFGF Treatment and Represent a Superb Tool for Immunosuppressive Clinical Applications.
Clinical Trial on Face & Skin, published in Int J Mol Sci (2020) — summary generated from the PubMed abstract.
- 2020
Int J Mol Sci22 citations - Level DLaboratory StudyPubMed
Assessment of the Immunosuppressive Potential of INF-γ Licensed Adipose Mesenchymal Stem Cells, Their Secretome and Extracellular Vesicles.
Laboratory Study on Immune Modulation, published in Cells (2019) — summary generated from the PubMed abstract.
- 2019
Cells - Level CProspective StudyEurope PMC
Tonsil-derived mesenchymal stem cells exert immunosuppressive effects on T cells
Prospective Study with a reported sample of 15 on Immune Modulation, published in Croat Med J (2019) — summary generated from the PubMed abstract.
- 2019
- n = 15
Croat Med J8 citations - Level DNarrative ReviewPubMed
Current understanding of the immunosuppressive properties of mesenchymal stromal cells.
Narrative Review on Neuroinflammation, Chronic Inflammation, Autoimmune Research, published in J Mol Med (Berl) (2019) — summary generated from the PubMed abstract.
- 2019
J Mol Med (Berl) - Level DLaboratory StudyEurope PMC
Comparison of Immunosuppressive and Angiogenic Properties of Human Amnion-Derived Mesenchymal Stem Cells between 2D and 3D Culture Systems
Laboratory Study on Immune Modulation, published in Stem Cells Int (2019) — summary generated from the PubMed abstract.
- 2019
Stem Cells Int76 citations - Level DAnimal StudyEurope PMC
NLGP counterbalances the immunosuppressive effect of tumor-associated mesenchymal stem cells to restore effector T cell functions
Animal Study on Immune Modulation, published in Stem Cell Res Ther (2019) — summary generated from the PubMed abstract.
- 2019
Stem Cell Res Ther16 citations - Level DAnimal StudyEurope PMC
Enhanced Immunosuppressive Properties of Human Mesenchymal Stem Cells Primed by Interferon-γ
Animal Study on Immune Modulation, published in EBioMedicine (2018) — summary generated from the PubMed abstract.
- 2018
EBioMedicine244 citations - Level DLaboratory StudyPubMed
B7‑H1‑mediated immunosuppressive properties in human mesenchymal stem cells are mediated by STAT‑1 and not PI3K/Akt signaling.
Laboratory Study, published in Mol Med Rep (2018) — summary generated from the PubMed abstract.
- 2018
Mol Med Rep - Level DLaboratory StudyPubMed
Pro inflammatory stimuli enhance the immunosuppressive functions of adipose mesenchymal stem cells-derived exosomes.
Laboratory Study on Chronic Inflammation, Immune Modulation, published in Sci Rep (2018) — summary generated from the PubMed abstract.
- 2018
Sci Rep207 citations - Level DNarrative ReviewPubMed
Contribution of microRNAs to the immunosuppressive function of mesenchymal stem cells.
Narrative Review on Chronic Inflammation, Immune Modulation, published in Biochimie (2018) — summary generated from the PubMed abstract.
- 2018
Biochimie - Level DAnimal StudyPubMed
Immunodepletion and Hypoxia Preconditioning of Mouse Compact Bone Cells as a Novel Protocol to Isolate Highly Immunosuppressive Mesenchymal Stem Cells.
Animal Study on Face & Skin, published in Stem Cells Dev (2017) — summary generated from the PubMed abstract.
- 2017
Stem Cells Dev - Level DLaboratory StudyPubMed
Brief Report: Proteasomal Indoleamine 2,3-Dioxygenase Degradation Reduces the Immunosuppressive Potential of Clinical Grade-Mesenchymal Stromal Cells Undergoing Replicative Senescence.
Laboratory Study on Immune Modulation, published in Stem Cells (2017) — summary generated from the PubMed abstract.
- 2017
Stem Cells34 citations - Level BClinical TrialPubMed
The effect of clinically relevant doses of immunosuppressive drugs on human mesenchymal stem cells.
Clinical Trial on Immune Modulation, published in Biomed Pharmacother (2017) — summary generated from the PubMed abstract.
- 2017
Biomed Pharmacother - Level DLaboratory StudyPubMed
Gelatin positively regulates the immunosuppressive capabilities of adipose-derived mesenchymal stem cells.
Laboratory Study on Immune Modulation, published in Turk J Biol (2017) — summary generated from the PubMed abstract.
- 2017
Turk J Biol5 citations - Level DAnimal StudyPubMed
Xenogeneic cardiac extracellular matrix scaffolds with or without seeded mesenchymal stem cells exhibit distinct in vivo immunosuppressive and regenerative properties.
Animal Study on Cardiovascular Disease, Chronic Inflammation, Immune Modulation, published in Acta Biomater (2016) — summary generated from the PubMed abstract.
- 2016
Acta Biomater
In-depth reviewed studies (full Thai translation)
Evidence system- Level ARandomized Controlled Trial
Cell-based versus corticosteroid injections for knee pain in osteoarthritis: a randomized phase 3 trial
A multicentre randomized trial in 480 knee osteoarthritis patients comparing SVF, BMAC and umbilical cord MSCs against corticosteroid injection. At 12 months no cell product outperformed the steroid control.
- 2023
- United States
- n = 480
- Level AMeta-analysis
Intra-articular Injection of Autologous Adipose-Derived Stem Cells or Stromal Vascular Fractions: Are They Effective for Patients With Knee Osteoarthritis? A Systematic Review With Meta-analysis of Randomized Controlled Trials
Pooled five RCTs comparing ADSC/SVF injection with placebo or hyaluronic acid, finding significant pain and function improvement at 6 and 12 months.
- 2023
- South Korea
- Level AMeta-analysis
Rapid-acting pain relief in knee osteoarthritis: autologous-cultured adipose-derived mesenchymal stem cells outperform stromal vascular fraction: a systematic review and meta-analysis
Analysed 31 studies with 1,406 patients: cultured ADMSCs reduced pain from month 3, whereas SVF reached significance only at 12 months.
- 2024
- South Korea
- n = 1406