Research database
SVF Research Library
Search 52,792 real PubMed studies on SVF and adipose-derived stem cells — 16 matching records.
16 results — page 1 of 1
- Level CProspective StudyPubMed
Metformin Promotes Osteogenic Differentiation of Adipose-Derived Stem Cells in Diabetic Osteoporosis by Regulating Autophagy.
Prospective Study on Face & Skin, Systemic / IV, published in Cell Biol Int (2025) — summary generated from the PubMed abstract.
- 2025
Cell Biol Int - Level DAnimal StudyPubMed
Metformin and adipose-derived stem cell combination therapy alleviates radiation-induced skin fibrosis in mice.
Animal Study, published in Stem Cell Res Ther (2024) — summary generated from the PubMed abstract.
- 2024
Stem Cell Res Ther9 citations - Level DAnimal StudyPubMed
Metformin promotes angiogenesis by enhancing VEGFa secretion by adipose-derived stem cells via the autophagy pathway.
Animal Study on Chronic Wound, published in Regen Biomater (2023) — summary generated from the PubMed abstract.
- 2023
Regen Biomater7 citations - Level CProspective StudyPubMed
Metformin Inhibits Lipid Droplets Fusion and Growth via Reduction in Cidec and Its Regulatory Factors in Rat Adipose-Derived Stem Cells.
Prospective Study, published in Int J Mol Sci (2022) — summary generated from the PubMed abstract.
- 2022
Int J Mol Sci10 citations - Level CProspective StudyPubMed
Metformin Ameliorates Senescence of Adipose-Derived Mesenchymal Stem Cells and Attenuates Osteoarthritis Progression via the AMPK-Dependent Autophagy Pathway.
Prospective Study on Osteoarthritis, published in Oxid Med Cell Longev (2022) — summary generated from the PubMed abstract.
- 2022
Oxid Med Cell Longev11 citations - Level DLaboratory StudyPubMed
Metformin and vitamin D modulate adipose-derived stem cell differentiation towards the beige phenotype.
Laboratory Study, published in Adipocyte (2022) — summary generated from the PubMed abstract.
- 2022
Adipocyte10 citations - Level DLaboratory StudyPubMed
Prolonged proliferation and delayed senescence of the adipose-derived stem cells grown on the electrospun composite nanofiber co-encapsulated with TiO 2 nanoparticles and metformin-loaded mesoporous silica nanoparticles.
Laboratory Study, published in Int J Pharm (2021) — summary generated from the PubMed abstract.
- 2021
Int J Pharm27 citations - Level DLaboratory StudyPubMed
Metformin and Vitamin D Modulate Inflammation and Autophagy during Adipose-Derived Stem Cell Differentiation.
Laboratory Study on Type 2 Diabetes, Chronic Inflammation, published in Int J Mol Sci (2021) — summary generated from the PubMed abstract.
- 2021
Int J Mol Sci18 citations - Level CProspective StudyPubMed
Metformin Rescues the Impaired Osteogenesis Differentiation Ability of Rat Adipose-Derived Stem Cells in High Glucose by Activating Autophagy.
Prospective Study on Systemic / IV, published in Stem Cells Dev (2021) — summary generated from the PubMed abstract.
- 2021
Stem Cells Dev20 citations - Level DAnimal StudyPubMed
Metformin Improves Stemness of Human Adipose-Derived Stem Cells by Downmodulation of Mechanistic Target of Rapamycin (mTOR) and Extracellular Signal-Regulated Kinase (ERK) Signaling.
Animal Study, published in Biomedicines (2021) — summary generated from the PubMed abstract.
- 2021
Biomedicines15 citations - Level DAnimal StudyPubMed
Metformin enhances the immunomodulatory potential of adipose-derived mesenchymal stem cells through STAT1 in an animal model of lupus.
Animal Study on Chronic Inflammation, Immune Modulation, Autoimmune Research, published in Rheumatology (Oxford) (2020) — summary generated from the PubMed abstract.
- 2020
Rheumatology (Oxford)48 citations - Level CProspective StudyPubMed
Effects of metformin on adipose-derived stromal cell (ADSC) - Breast cancer cell lines interaction.
Prospective Study on Type 2 Diabetes, published in Life Sci (2020) — summary generated from the PubMed abstract.
- 2020
Life Sci11 citations - Level DAnimal StudyPubMed
Metformin Promotes Osteogenic Differentiation of Adipose-Derived Stromal Cells and Exerts Pro-Osteogenic Effect Stimulating Bone Regeneration.
Animal Study on Type 2 Diabetes, published in J Clin Med (2018) — summary generated from the PubMed abstract.
- 2018
J Clin Med41 citations - Level DAnimal StudyPubMed
Metformin Decreases Reactive Oxygen Species, Enhances Osteogenic Properties of Adipose-Derived Multipotent Mesenchymal Stem Cells In Vitro, and Increases Bone Density In Vivo.
Animal Study on Systemic / IV, published in Oxid Med Cell Longev (2016) — summary generated from the PubMed abstract.
- 2016
Oxid Med Cell Longev74 citations - Level DAnimal StudyPubMed
Metformin preconditioned adipose derived mesenchymal stem cells is a better option for the reversal of diabetes upon transplantation.
Animal Study on Type 2 Diabetes, published in Biomed Pharmacother (2016) — summary generated from the PubMed abstract.
- 2016
Biomed Pharmacother14 citations - Level DAnimal StudyPubMed
In Vitro and In Vivo Effects of Metformin on Osteopontin Expression in Mice Adipose-Derived Multipotent Stromal Cells and Adipose Tissue.
Animal Study on Hip, Systemic / IV, published in J Diabetes Res (2015) — summary generated from the PubMed abstract.
- 2015
J Diabetes Res17 citations
In-depth reviewed studies (full Thai translation)
Evidence system- Level ARandomized Controlled Trial
Cell-based versus corticosteroid injections for knee pain in osteoarthritis: a randomized phase 3 trial
A multicentre randomized trial in 480 knee osteoarthritis patients comparing SVF, BMAC and umbilical cord MSCs against corticosteroid injection. At 12 months no cell product outperformed the steroid control.
- 2023
- United States
- n = 480
- Level AMeta-analysis
Intra-articular Injection of Autologous Adipose-Derived Stem Cells or Stromal Vascular Fractions: Are They Effective for Patients With Knee Osteoarthritis? A Systematic Review With Meta-analysis of Randomized Controlled Trials
Pooled five RCTs comparing ADSC/SVF injection with placebo or hyaluronic acid, finding significant pain and function improvement at 6 and 12 months.
- 2023
- South Korea
- Level AMeta-analysis
Rapid-acting pain relief in knee osteoarthritis: autologous-cultured adipose-derived mesenchymal stem cells outperform stromal vascular fraction: a systematic review and meta-analysis
Analysed 31 studies with 1,406 patients: cultured ADMSCs reduced pain from month 3, whereas SVF reached significance only at 12 months.
- 2024
- South Korea
- n = 1406