Research database
SVF Research Library
Search 52,792 real PubMed studies on SVF and adipose-derived stem cells — 27 matching records.
27 results — page 1 of 2
- Level DNarrative ReviewEurope PMC
Automated Manufacturing Processes and Platforms for Large-scale Production of Clinical-grade Mesenchymal Stem/ Stromal Cells
Narrative Review on Immune Modulation, published in Stem Cell Rev Rep (2025) — summary generated from the PubMed abstract.
- 2025
Stem Cell Rev Rep28 citations - Level DAnimal StudyEurope PMC
Enucleated bone marrow-derived mesenchymal stromal cells regulate immune microenvironment and promote testosterone production through efferocytosis
Animal Study, published in Reprod Biol Endocrinol (2025) — summary generated from the PubMed abstract.
- 2025
Reprod Biol Endocrinol8 citations - Level BClinical TrialPubMed
A Narrative Review on Manufacturing Methods Employed in the Production of Mesenchymal Stromal Cells for Knee Osteoarthritis Therapy.
Clinical Trial on Knee Osteoarthritis, Osteoarthritis, Immune Modulation, published in Biomedicines (2025) — summary generated from the PubMed abstract.
- 2025
Biomedicines1 citations - Level DNarrative ReviewEurope PMC
Effects of Hydrogels on Mesenchymal Stem/Stromal Cells Paracrine Activity and Extracellular Vesicles Production
Narrative Review on Immune Modulation, published in J Extracell Vesicles (2025) — summary generated from the PubMed abstract.
- 2025
J Extracell Vesicles20 citations - Level BClinical TrialPubMed
Impact of cell culture transition on adipose-derived mesenchymal stromal cells: Multi-omics analysis of small- vs large-scale production.
Clinical Trial on Immune Modulation, published in Mol Ther Methods Clin Dev (2025) — summary generated from the PubMed abstract.
- 2025
Mol Ther Methods Clin Dev - Level DLaboratory StudyPubMed
Dynamic cultivation of human mesenchymal stem/stromal cells for the production of extracellular vesicles in a 3D bioreactor system.
Laboratory Study on Face & Skin, published in Biotechnol Lett (2024) — summary generated from the PubMed abstract.
- 2024
Biotechnol Lett11 citations - Level CProspective StudyPubMed
Culture of Hoffa fat pad mesenchymal stem/stromal cells on microcarrier suspension in vertical wheel bioreactor for extracellular vesicle production.
Prospective Study on Osteoarthritis, Chronic Inflammation, Immune Modulation, published in Stem Cell Res Ther (2024) — summary generated from the PubMed abstract.
- 2024
Stem Cell Res Ther11 citations - Level DAnimal StudyPubMed
Extracellular vesicles derived from bovine adipose-derived mesenchymal stromal cells enhance in vitro embryo production from lesioned ovaries.
Animal Study with a reported sample of 5, published in Cytotherapy (2024) — summary generated from the PubMed abstract.
- 2024
- n = 5
Cytotherapy5 citations - Level DAnimal StudyPubMed
Co-culture of vascular endothelial cells enhances corticosterone production in steroid hormone-producing cells generated from adipose-derived mesenchymal stromal cells.
Animal Study on Systemic / IV, published in Sci Rep (2024) — summary generated from the PubMed abstract.
- 2024
Sci Rep2 citations - Level DLaboratory StudyEurope PMC
Hollow fiber bioreactor allows sustained production of immortalized mesenchymal stromal cell-derived extracellular vesicles
Laboratory Study, published in Extracell Vesicles Circ Nucl Acids (2024) — summary generated from the PubMed abstract.
- 2024
Extracell Vesicles Circ Nucl Acids21 citations - Level DAnimal StudyEurope PMC
Significant expansion of the donor pool achieved by utilizing islets of variable quality in the production of allogeneic "Neo-Islets", 3-D organoids of Mesenchymal Stromal and islet cells, a novel immune-isolating biothe
Animal Study with a reported sample of 6 on Type 1 Diabetes, Chronic Inflammation, Autoimmune Research, published in PLoS One (2023) — summary generated from the PubMed abstract.
- 2023
- n = 6
PLoS One3 citations - Level DLaboratory StudyPubMed
Equine Mesenchymal Stem/Stromal Cells Freeze-Dried Secretome (Lyosecretome) for the Treatment of Musculoskeletal Diseases: Production Process Validation and Batch Release Test for Clinical Use.
Laboratory Study on Face & Skin, published in Pharmaceuticals (Basel) (2021) — summary generated from the PubMed abstract.
- 2021
Pharmaceuticals (Basel)18 citations - Level DLaboratory StudyPubMed
Automated Large-Scale Production of Paclitaxel Loaded Mesenchymal Stromal Cells for Cell Therapy Applications.
Laboratory Study, published in Pharmaceutics (2020) — summary generated from the PubMed abstract.
- 2020
Pharmaceutics21 citations - Level DLaboratory StudyPubMed
Scalable Production of Human Mesenchymal Stromal Cell-Derived Extracellular Vesicles Under Serum-/Xeno-Free Conditions in a Microcarrier-Based Bioreactor Culture System.
Laboratory Study with a reported sample of 3 on Immune Modulation, published in Front Cell Dev Biol (2020) — summary generated from the PubMed abstract.
- 2020
- n = 3
Front Cell Dev Biol - Level DLaboratory StudyPubMed
Scalable Production of Equine Platelet Lysate for Multipotent Mesenchymal Stromal Cell Culture.
Laboratory Study on Face & Skin, published in Front Bioeng Biotechnol (2020) — summary generated from the PubMed abstract.
- 2020
Front Bioeng Biotechnol - Level DLaboratory StudyEurope PMC
Adaptive Regulation of Osteopontin Production by Dendritic Cells Through the Bidirectional Interaction With Mesenchymal Stromal Cells
Laboratory Study, published in Front Immunol (2018) — summary generated from the PubMed abstract.
- 2018
Front Immunol23 citations - Level DLaboratory StudyEurope PMC
Pilot Production of Mesenchymal Stem/Stromal Freeze-Dried Secretome for Cell-Free Regenerative Nanomedicine: A Validated GMP-Compliant Process
Laboratory Study, published in Cells (2018) — summary generated from the PubMed abstract.
- 2018
Cells136 citations - Level DLaboratory StudyPubMed
Amniotic Mesenchymal Stromal Cells Exhibit Preferential Osteogenic and Chondrogenic Differentiation and Enhanced Matrix Production Compared With Adipose Mesenchymal Stromal Cells.
Laboratory Study on Cartilage Damage, published in Am J Sports Med (2017) — summary generated from the PubMed abstract.
- 2017
Am J Sports Med36 citations - Level CCohort StudyPubMed
Identification and validation of multiple cell surface markers of clinical-grade adipose-derived mesenchymal stromal cells as novel release criteria for good manufacturing practice-compliant production.
Cohort Study on Knee Osteoarthritis, Osteoarthritis, published in Stem Cell Res Ther (2016) — summary generated from the PubMed abstract.
- 2016
Stem Cell Res Ther133 citations - Level DLaboratory StudyPubMed
Proinflammatory interleukins' production by adipose tissue-derived mesenchymal stromal cells: the impact of cell culture conditions and cell-to-cell interaction.
Laboratory Study, published in Cell Biochem Funct (2015) — summary generated from the PubMed abstract.
- 2015
Cell Biochem Funct4 citations - Level DAnimal StudyPubMed
Mesenchymal stromal (stem) cells suppress pro-inflammatory cytokine production but fail to improve survival in experimental staphylococcal toxic shock syndrome.
Animal Study on Chronic Inflammation, Immune Modulation, published in BMC Immunol (2014) — summary generated from the PubMed abstract.
- 2014
BMC Immunol - Level DLaboratory StudyPubMed
Immortalization of human adipose-derived stromal cells: production of cell lines with high growth rate, mesenchymal marker expression and capability to secrete high levels of angiogenic factors.
Laboratory Study, published in Stem Cell Res Ther (2014) — summary generated from the PubMed abstract.
- 2014
Stem Cell Res Ther60 citations - Level DLaboratory StudyPubMed
Mesenchymal stromal cell proliferation, gene expression and protein production in human platelet-rich plasma-supplemented media.
Laboratory Study on Face & Skin, Hip, published in PLoS One (2014) — summary generated from the PubMed abstract.
- 2014
PLoS One - Level DAnimal StudyPubMed
A therapeutic strategy for metastatic malignant fibrous histiocytoma through mesenchymal stromal cell-mediated TRAIL production.
Animal Study, published in Ann Surg (2013) — summary generated from the PubMed abstract.
- 2013
Ann Surg
In-depth reviewed studies (full Thai translation)
Evidence system- Level ARandomized Controlled Trial
Cell-based versus corticosteroid injections for knee pain in osteoarthritis: a randomized phase 3 trial
A multicentre randomized trial in 480 knee osteoarthritis patients comparing SVF, BMAC and umbilical cord MSCs against corticosteroid injection. At 12 months no cell product outperformed the steroid control.
- 2023
- United States
- n = 480
- Level AMeta-analysis
Intra-articular Injection of Autologous Adipose-Derived Stem Cells or Stromal Vascular Fractions: Are They Effective for Patients With Knee Osteoarthritis? A Systematic Review With Meta-analysis of Randomized Controlled Trials
Pooled five RCTs comparing ADSC/SVF injection with placebo or hyaluronic acid, finding significant pain and function improvement at 6 and 12 months.
- 2023
- South Korea
- Level AMeta-analysis
Rapid-acting pain relief in knee osteoarthritis: autologous-cultured adipose-derived mesenchymal stem cells outperform stromal vascular fraction: a systematic review and meta-analysis
Analysed 31 studies with 1,406 patients: cultured ADMSCs reduced pain from month 3, whereas SVF reached significance only at 12 months.
- 2024
- South Korea
- n = 1406