Research database
SVF Research Library
Search 52,792 real PubMed studies on SVF and adipose-derived stem cells — 33 matching records.
33 results — page 1 of 2
- Level DNarrative ReviewEurope PMC
Exploring the Complexities of TGF-β Signaling in Keloids: Beyond the Classical Smad Pathway
Narrative Review on Scar, Chronic Inflammation, published in Int J Mol Sci (2026) — summary generated from the PubMed abstract.
- 2026
Int J Mol Sci2 citations - Level DAnimal StudyPubMed
miR-574-3p and miR-125a-5p in Adipose-Derived Mesenchymal Stem Cell Exosomes Synergistically Target TGF-β1/SMAD2 Signaling Pathway for the Treatment of Androgenic Alopecia.
Animal Study on Chronic Wound, Hair Loss, published in J Invest Dermatol (2025) — summary generated from the PubMed abstract.
- 2025
J Invest Dermatol4 citations - Level DAnimal StudyPubMed
Investigating the regulation of the miR-199a-3p/TGF-β/Smad signaling pathway by BSHXF drug-containing serum combined with ADSCs for delaying intervertebral disc degeneration.
Animal Study on Back Pain, Disc Degeneration, Scar, published in Front Pharmacol (2025) — summary generated from the PubMed abstract.
- 2025
Front Pharmacol1 citations - Level DAnimal StudyPubMed
Adipose-derived stem cell exosomes alleviate TGF-β1-induced urethral stricture fibrosis by suppressing the TGF-β/Smad pathway and downstream PDGFR-β/RAS/ERK signaling.
Animal Study, published in J Cell Commun Signal (2025) — summary generated from the PubMed abstract.
- 2025
J Cell Commun Signal - Level DAnimal StudyEurope PMC
GDF15 promotes osteogenic differentiation of human dental pulp stem cells by activating the TGF-β/SMAD signaling pathway
Animal Study on Face & Skin, published in J Tissue Eng (2025) — summary generated from the PubMed abstract.
- 2025
J Tissue Eng2 citations - Level DAnimal StudyPubMed
Extracellular Vesicles Derived from Type 2 Diabetic Mesenchymal Stem Cells Induce Endothelial Mesenchymal Transition under High Glucose Conditions Through the TGFβ/Smad3 Signaling Pathway.
Animal Study on Type 2 Diabetes, Chronic Wound, published in Stem Cells Dev (2024) — summary generated from the PubMed abstract.
- 2024
Stem Cells Dev - Level DLaboratory StudyPubMed
In vitro Chondrogenic Induction Promotes the Expression Level of IL-10 via the TGF-β/SMAD and Canonical Wnt/β-catenin Signaling Pathways in Exosomes Secreted by Human Adipose Tissue-derived Mesenchymal Stem Cells.
Laboratory Study on Cartilage Damage, published in Cell Biochem Biophys (2024) — summary generated from the PubMed abstract.
- 2024
Cell Biochem Biophys - Level DLaboratory StudyPubMed
Adipose Mesenchymal Stromal Cell-Derived Exosomes Carrying MiR-122-5p Antagonize the Inhibitory Effect of Dihydrotestosterone on Hair Follicles by Targeting the TGF-β1/SMAD3 Signaling Pathway.
Laboratory Study on Hair Loss, published in Int J Mol Sci (2023) — summary generated from the PubMed abstract.
- 2023
Int J Mol Sci56 citations - Level DLaboratory StudyEurope PMC
Simulated microgravity altered the proliferation, apoptosis, and extracellular matrix formation of L929 fibroblasts and the transforming growth factor-β1/Smad3 signaling pathway
Laboratory Study on Chronic Wound, Scar, published in Skin Res Technol (2023) — summary generated from the PubMed abstract.
- 2023
Skin Res Technol12 citations - Level DAnimal StudyEurope PMC
miR-10a-3p modulates adiposity and suppresses adipose inflammation through TGF-β1/Smad3 signaling pathway
Animal Study on Chronic Inflammation, published in Front Immunol (2023) — summary generated from the PubMed abstract.
- 2023
Front Immunol14 citations - Level DAnimal StudyEurope PMC
Amniotic fluid-derived exosomes attenuated fibrotic changes in POI rats through modulation of the TGF-β/Smads signaling pathway
Animal Study on Hair & Scalp, published in J Ovarian Res (2023) — summary generated from the PubMed abstract.
- 2023
J Ovarian Res31 citations - Level DLaboratory StudyPubMed
Adipose-derived stem cells repair radiation-induced chronic lung injury via inhibiting TGF-β1/Smad 3 signaling pathway.
Laboratory Study, published in Open Med (Wars) (2023) — summary generated from the PubMed abstract.
- 2023
Open Med (Wars)2 citations - Level DAnimal StudyEurope PMC
Long non‑coding RNA MBI‑52 inhibits the development of liver fibrosis by regulating the microRNA‑466g/SMAD4 signaling pathway
Animal Study on Chronic Wound, published in Mol Med Rep (2022) — summary generated from the PubMed abstract.
- 2022
Mol Med Rep6 citations - Level DAnimal StudyEurope PMC
Exosome-delivered BMP-2 and polyaspartic acid promotes tendon bone healing in rotator cuff tear via Smad/RUNX2 signaling pathway
Animal Study on Tendon Injury, Rotator Cuff, published in Bioengineered (2022) — summary generated from the PubMed abstract.
- 2022
Bioengineered43 citations - Level DLaboratory StudyPubMed
Paracrine effect of the stromal vascular fraction containing M2 macrophages on human chondrocytes through the Smad2/3 signaling pathway.
Laboratory Study on Osteoarthritis, Chronic Inflammation, published in J Cell Physiol (2022) — summary generated from the PubMed abstract.
- 2022
J Cell Physiol12 citations - Level DLaboratory StudyEurope PMC
MiR-20a: a mechanosensitive microRNA that regulates fluid shear stress-mediated osteogenic differentiation via the BMP2 signaling pathway by targeting BAMBI and SMAD6
Laboratory Study, published in Ann Transl Med (2022) — summary generated from the PubMed abstract.
- 2022
Ann Transl Med16 citations - Level DAnimal StudyPubMed
Adipose-Derived Stem Cells (ADSCs) Supplemented with Hepatocyte Growth Factor (HGF) Attenuate Hepatic Stellate Cell Activation and Liver Fibrosis by Inhibiting the TGF-β/Smad Signaling Pathway in Chemical-Induced Liver F
Animal Study on Systemic / IV, published in Cells (2022) — summary generated from the PubMed abstract.
- 2022
Cells23 citations - Level DAnimal StudyPubMed
Repair abilities of mouse autologous adipose-derived stem cells and ShakeGel™3D complex local injection with intrauterine adhesion by BMP7-Smad5 signaling pathway activation.
Animal Study, published in Stem Cell Res Ther (2021) — summary generated from the PubMed abstract.
- 2021
Stem Cell Res Ther19 citations - Level CProspective StudyEurope PMC
Epigallocatechin-3-Gallate Promotes Osteo-/Odontogenic Differentiation of Stem Cells from the Apical Papilla through Activating the BMP-Smad Signaling Pathway
Prospective Study with a reported sample of 5, published in Molecules (2021) — summary generated from the PubMed abstract.
- 2021
- n = 5
Molecules30 citations - Level CProspective StudyEurope PMC
Recombinant TSG-6 protein inhibits the growth of capsule fibroblasts in frozen shoulder via suppressing the TGF-β/Smad2 signal pathway
Prospective Study on Chronic Inflammation, published in J Orthop Surg Res (2021) — summary generated from the PubMed abstract.
- 2021
J Orthop Surg Res14 citations - Level DAnimal StudyPubMed
Autophagy Promotes the Survival of Adipose Mesenchymal Stem/Stromal Cells and Enhances Their Therapeutic Effects in Cisplatin-Induced Liver Injury via Modulating TGF-β1/Smad and PI3K/AKT Signaling Pathways.
Animal Study, published in Cells (2021) — summary generated from the PubMed abstract.
- 2021
Cells23 citations - Level DLaboratory StudyPubMed
ALK5 i II Accelerates Induction of Adipose-Derived Stem Cells toward Schwann Cells through a Non-Smad Signaling Pathway.
Laboratory Study, published in Stem Cells Int (2021) — summary generated from the PubMed abstract.
- 2021
Stem Cells Int4 citations - Level DAnimal StudyPubMed
AT-MSCs Antifibrotic Activity is Improved by Eugenol through Modulation of TGF-β/Smad Signaling Pathway in Rats.
Animal Study, published in Molecules (2020) — summary generated from the PubMed abstract.
- 2020
Molecules - Level DLaboratory StudyEurope PMC
Effect of CD44 on differentiation of human amniotic mesenchymal stem cells into chondrocytes via Smad and ERK signaling pathways
Laboratory Study, published in Mol Med Rep (2020) — summary generated from the PubMed abstract.
- 2020
Mol Med Rep23 citations
In-depth reviewed studies (full Thai translation)
Evidence system- Level ARandomized Controlled Trial
Cell-based versus corticosteroid injections for knee pain in osteoarthritis: a randomized phase 3 trial
A multicentre randomized trial in 480 knee osteoarthritis patients comparing SVF, BMAC and umbilical cord MSCs against corticosteroid injection. At 12 months no cell product outperformed the steroid control.
- 2023
- United States
- n = 480
- Level AMeta-analysis
Intra-articular Injection of Autologous Adipose-Derived Stem Cells or Stromal Vascular Fractions: Are They Effective for Patients With Knee Osteoarthritis? A Systematic Review With Meta-analysis of Randomized Controlled Trials
Pooled five RCTs comparing ADSC/SVF injection with placebo or hyaluronic acid, finding significant pain and function improvement at 6 and 12 months.
- 2023
- South Korea
- Level AMeta-analysis
Rapid-acting pain relief in knee osteoarthritis: autologous-cultured adipose-derived mesenchymal stem cells outperform stromal vascular fraction: a systematic review and meta-analysis
Analysed 31 studies with 1,406 patients: cultured ADMSCs reduced pain from month 3, whereas SVF reached significance only at 12 months.
- 2024
- South Korea
- n = 1406