Research database
SVF Research Library
Search 52,792 real PubMed studies on SVF and adipose-derived stem cells — 4 matching records.
4 results — page 1 of 1
- Level DLaboratory StudyPubMed
Prostaglandin E 2 down-regulates sirtuin 1 (SIRT1), leading to elevated levels of aromatase, providing insights into the obesity-breast cancer connection.
Laboratory Study, published in J Biol Chem (2018) — summary generated from the PubMed abstract.
- 2018
J Biol Chem - Level CProspective StudyPubMed
Hsp90 and PKM2 Drive the Expression of Aromatase in Li-Fraumeni Syndrome Breast Adipose Stromal Cells.
Prospective Study, published in J Biol Chem (2016) — summary generated from the PubMed abstract.
- 2016
J Biol Chem - Level CProspective StudyEurope PMC
Increased levels of COX-2 and prostaglandin E2 contribute to elevated aromatase expression in inflamed breast tissue of obese women
Prospective Study on Chronic Inflammation, published in Cancer Discov (2012) — summary generated from the PubMed abstract.
- 2012
Cancer Discov190 citations - Level DAnimal StudyEurope PMC
Obesity is associated with inflammation and elevated aromatase expression in the mouse mammary gland
Animal Study on Systemic / IV, published in Cancer Prev Res (Phila) (2011) — summary generated from the PubMed abstract.
- 2011
Cancer Prev Res (Phila)292 citations
In-depth reviewed studies (full Thai translation)
Evidence system- Level ARandomized Controlled Trial
Cell-based versus corticosteroid injections for knee pain in osteoarthritis: a randomized phase 3 trial
A multicentre randomized trial in 480 knee osteoarthritis patients comparing SVF, BMAC and umbilical cord MSCs against corticosteroid injection. At 12 months no cell product outperformed the steroid control.
- 2023
- United States
- n = 480
- Level AMeta-analysis
Intra-articular Injection of Autologous Adipose-Derived Stem Cells or Stromal Vascular Fractions: Are They Effective for Patients With Knee Osteoarthritis? A Systematic Review With Meta-analysis of Randomized Controlled Trials
Pooled five RCTs comparing ADSC/SVF injection with placebo or hyaluronic acid, finding significant pain and function improvement at 6 and 12 months.
- 2023
- South Korea
- Level AMeta-analysis
Rapid-acting pain relief in knee osteoarthritis: autologous-cultured adipose-derived mesenchymal stem cells outperform stromal vascular fraction: a systematic review and meta-analysis
Analysed 31 studies with 1,406 patients: cultured ADMSCs reduced pain from month 3, whereas SVF reached significance only at 12 months.
- 2024
- South Korea
- n = 1406