Research database
SVF Research Library
Search 52,792 real PubMed studies on SVF and adipose-derived stem cells — 18 matching records.
18 results — page 1 of 1
- Level CProspective StudyPubMed
ADSC exosomes improve high glucose induced fibroblast oxidative stress injury and accelerate DFU wound healing via regulating Keap1/Nrf2 axis.
Prospective Study on Diabetic Foot, Chronic Wound, published in Cell Signal (2025) — summary generated from the PubMed abstract.
- 2025
Cell Signal - Level DAnimal StudyPubMed
Adipose-derived mesenchymal stem cell exosomes protect keratinocytes from high-glucose injury by modulating KEAP1/NRF2/HO-1 axis.
Animal Study on Diabetic Foot, Chronic Wound, published in Cell Signal (2025) — summary generated from the PubMed abstract.
- 2025
Cell Signal - Level DAnimal StudyPubMed
GKT137831 in combination with adipose-derived stem cells alleviates high glucose-induced inflammaging and improves diabetic wound healing.
Animal Study on Diabetic Foot, Chronic Wound, published in J Leukoc Biol (2024) — summary generated from the PubMed abstract.
- 2024
J Leukoc Biol1 citations - Level DAnimal StudyPubMed
Extracellular Vesicles Derived from Type 2 Diabetic Mesenchymal Stem Cells Induce Endothelial Mesenchymal Transition under High Glucose Conditions Through the TGFβ/Smad3 Signaling Pathway.
Animal Study on Type 2 Diabetes, Chronic Wound, published in Stem Cells Dev (2024) — summary generated from the PubMed abstract.
- 2024
Stem Cells Dev - Level DLaboratory StudyPubMed
Adipose stem cell‑derived exosomes promote high glucose-induced wound healing by regulating the TRIM32/STING axis.
Laboratory Study on Diabetic Foot, Chronic Wound, published in Arch Dermatol Res (2024) — summary generated from the PubMed abstract.
- 2024
Arch Dermatol Res2 citations - Level DAnimal StudyPubMed
Adipose mesenchymal stem cell-derived extracellular vesicles regulate PINK1/parkin-mediated mitophagy to repair high glucose-induced dermal fibroblast senescence and promote wound healing in rats with diabetic foot ulcer
Animal Study on Diabetic Foot, Chronic Wound, published in Acta Diabetol (2024) — summary generated from the PubMed abstract.
- 2024
Acta Diabetol - Level CProspective StudyEurope PMC
High glucose-induced IL-7/IL-7R upregulation of dermal fibroblasts inhibits angiogenesis in a paracrine way in delayed diabetic wound healing
Prospective Study on Diabetic Foot, Chronic Wound, published in J Cell Commun Signal (2023) — summary generated from the PubMed abstract.
- 2023
J Cell Commun Signal15 citations - Level DAnimal StudyEurope PMC
P-MSC-derived extracellular vesicles facilitate diabetic wound healing via miR-145-5p/ CDKN1A-mediated functional improvements of high glucose-induced senescent fibroblasts
Animal Study on Diabetic Foot, Chronic Wound, Scar, published in Burns Trauma (2023) — summary generated from the PubMed abstract.
- 2023
Burns Trauma38 citations - Level CProspective StudyPubMed
Effects of High Glucose Concentration on Pericyte-Like Differentiated Human Adipose-Derived Mesenchymal Stem Cells.
Prospective Study on Chronic Inflammation, published in Int J Mol Sci (2021) — summary generated from the PubMed abstract.
- 2021
Int J Mol Sci18 citations - Level AMeta-analysisEurope PMC
Wharton's Jelly Mesenchymal Stem Cell-Derived Extracellular Vesicles Reduce SARS-CoV2-Induced Inflammatory Cytokines Under High Glucose and Uremic Toxin Conditions
Meta-analysis with a reported sample of 19 on Chronic Inflammation, Immune Modulation, published in Stem Cells Dev (2021) — summary generated from the PubMed abstract.
- 2021
- n = 19
Stem Cells Dev22 citations - Level DAnimal StudyPubMed
HIF1α overexpression enhances diabetic wound closure in high glucose and low oxygen conditions by promoting adipose-derived stem cell paracrine function and survival.
Animal Study on Diabetic Foot, Chronic Wound, published in Stem Cell Res Ther (2020) — summary generated from the PubMed abstract.
- 2020
Stem Cell Res Ther49 citations - Level DAnimal StudyPubMed
Chronic high glucose and insulin stimulate bone-marrow stromal cells adipogenic differentiation in young spontaneously hypertensive rats.
Animal Study, published in J Cell Physiol (2018) — summary generated from the PubMed abstract.
- 2018
J Cell Physiol - Level DAnimal StudyEurope PMC
Dietary yeast-derived mannan oligosaccharides have immune-modulatory properties but do not improve high fat diet-induced obesity and glucose intolerance
Animal Study on Chronic Inflammation, published in PLoS One (2018) — summary generated from the PubMed abstract.
- 2018
PLoS One17 citations - Level DAnimal StudyPubMed
Human adipose tissue-derived stromal cells act as functional pericytes in mice and suppress high-glucose-induced proinflammatory activation of bovine retinal endothelial cells.
Animal Study on Chronic Wound, Immune Modulation, published in Diabetologia (2018) — summary generated from the PubMed abstract.
- 2018
Diabetologia - Level CProspective StudyPubMed
Impaired cutaneous T-cell attracting chemokine elevation and adipose-derived stromal cell migration in a high-glucose environment cause poor diabetic wound healing.
Prospective Study on Diabetic Foot, Chronic Wound, published in Kaohsiung J Med Sci (2018) — summary generated from the PubMed abstract.
- 2018
Kaohsiung J Med Sci12 citations - Level BRandomized Controlled TrialEurope PMC
No differential effect of beverages sweetened with fructose, high-fructose corn syrup, or glucose on systemic or adipose tissue inflammation in normal-weight to obese adults: a randomized controlled trial
Randomized Controlled Trial on Type 2 Diabetes, Chronic Inflammation, published in Am J Clin Nutr (2016) — summary generated from the PubMed abstract.
- 2016
Am J Clin Nutr36 citations - Level DLaboratory StudyPubMed
Epigenetic priming of inflammatory response genes by high glucose in adipose progenitor cells.
Laboratory Study on Chronic Inflammation, published in Biochem Biophys Res Commun (2015) — summary generated from the PubMed abstract.
- 2015
Biochem Biophys Res Commun - Level CProspective StudyPubMed
BBS-induced ciliary defect enhances adipogenesis, causing paradoxical higher-insulin sensitivity, glucose usage, and decreased inflammatory response.
Prospective Study on Type 2 Diabetes, Chronic Inflammation, published in Cell Metab (2012) — summary generated from the PubMed abstract.
- 2012
Cell Metab
In-depth reviewed studies (full Thai translation)
Evidence system- Level ARandomized Controlled Trial
Cell-based versus corticosteroid injections for knee pain in osteoarthritis: a randomized phase 3 trial
A multicentre randomized trial in 480 knee osteoarthritis patients comparing SVF, BMAC and umbilical cord MSCs against corticosteroid injection. At 12 months no cell product outperformed the steroid control.
- 2023
- United States
- n = 480
- Level AMeta-analysis
Intra-articular Injection of Autologous Adipose-Derived Stem Cells or Stromal Vascular Fractions: Are They Effective for Patients With Knee Osteoarthritis? A Systematic Review With Meta-analysis of Randomized Controlled Trials
Pooled five RCTs comparing ADSC/SVF injection with placebo or hyaluronic acid, finding significant pain and function improvement at 6 and 12 months.
- 2023
- South Korea
- Level AMeta-analysis
Rapid-acting pain relief in knee osteoarthritis: autologous-cultured adipose-derived mesenchymal stem cells outperform stromal vascular fraction: a systematic review and meta-analysis
Analysed 31 studies with 1,406 patients: cultured ADMSCs reduced pain from month 3, whereas SVF reached significance only at 12 months.
- 2024
- South Korea
- n = 1406