Research database
SVF Research Library
Search 52,792 real PubMed studies on SVF and adipose-derived stem cells — 18 matching records.
18 results — page 1 of 1
Expanded search to: exosome, extracellular vesicle, secretome
- Level DAnimal StudyPubMed
Extracellular vesicles derived from adipose-derived mesenchymal stem/stromal cells prevent synovial inflammation and attenuate cartilage degeneration in rodent osteoarthritis.
Animal Study on Osteoarthritis, Cartilage Damage, Chronic Inflammation, Immune Modulation, published in Regen Ther (2026) — summary generated from the PubMed abstract.
- 2026
Regen Ther - Level DNarrative ReviewEurope PMC
Mesenchymal stem cell and exosome-based therapies for degenerative disc disease: from mechanisms to clinical translation
Narrative Review on Back Pain, Disc Degeneration, Chronic Inflammation, published in Front Cell Dev Biol (2026) — summary generated from the PubMed abstract.
- 2026
Front Cell Dev Biol - Level DAnimal StudyEurope PMC
Heme oxygenase 1‑overexpressing bone marrow mesenchymal stem cell‑derived exosomes suppress interleukin‑1 beta‑induced apoptosis and aging of nucleus pulposus cells
Animal Study on Disc Degeneration, published in Mol Med Rep (2025) — summary generated from the PubMed abstract.
- 2025
Mol Med Rep1 citations - Level DAnimal StudyPubMed
tsRNA-12391-Modified Adipose Mesenchymal Stem Cell-Derived Exosomes Mitigate Cartilage Degeneration in Osteoarthritis by Enhancing Mitophagy.
Animal Study on Osteoarthritis, published in Biotechnol J (2025) — summary generated from the PubMed abstract.
- 2025
Biotechnol J - Level CProspective StudyEurope PMC
Insulin-Enhanced Biological Visual Rehabilitation in Neuroretinal Degeneration Patients Treated with Mesenchymal Cell-Derived Secretome
Prospective Study on Neuroinflammation, published in Pharmaceutics (2025) — summary generated from the PubMed abstract.
- 2025
Pharmaceutics - Level DNarrative ReviewPubMed
Adipose Mesenchymal Stem Cell-Derived Exosomes as Nanocarriers for Treating Musculoskeletal Disorders.
Narrative Review on Osteoarthritis, Tendon Injury, Disc Degeneration, published in Int J Nanomedicine (2024) — summary generated from the PubMed abstract.
- 2024
Int J Nanomedicine13 citations - Level DNarrative ReviewPubMed
Nanoscale Treatment of Intervertebral Disc Degeneration: Mesenchymal Stem Cell Exosome Transplantation.
Narrative Review on Disc Degeneration, published in Curr Stem Cell Res Ther (2023) — summary generated from the PubMed abstract.
- 2023
Curr Stem Cell Res Ther15 citations - Level DLaboratory StudyPubMed
Mesenchymal stem cell-derived secretome enhances nucleus pulposus cell metabolism and modulates extracellular matrix gene expression in vitro .
Laboratory Study on Back Pain, Disc Degeneration, published in Front Bioeng Biotechnol (2023) — summary generated from the PubMed abstract.
- 2023
Front Bioeng Biotechnol22 citations - Level CProspective StudyPubMed
Extracellular vesicle and soluble fractions of adipose tissue-derived mesenchymal stem cells secretome induce inflammatory cytokines modulation in an in vitro model of discogenic pain.
Prospective Study with a reported sample of 3 on Back Pain, Disc Degeneration, Chronic Inflammation, published in Spine J (2022) — summary generated from the PubMed abstract.
- 2022
- n = 3
Spine J - Level DNarrative ReviewEurope PMC
Mesenchymal Stem Cell-Derived Exosomes and Intervertebral Disc Regeneration: Review
Narrative Review on Back Pain, Disc Degeneration, Chronic Inflammation, published in Int J Mol Sci (2022) — summary generated from the PubMed abstract.
- 2022
Int J Mol Sci69 citations - Level DAnimal StudyEurope PMC
Bone Marrow Mesenchymal Stem Cell-Derived Extracellular Vesicles Carrying circ_0050205 Attenuate Intervertebral Disc Degeneration
Animal Study on Disc Degeneration, published in Oxid Med Cell Longev (2022) — summary generated from the PubMed abstract.
- 2022
Oxid Med Cell Longev15 citations - Level DNarrative ReviewEurope PMC
Application of mesenchymal stem cell-derived exosomes from different sources in intervertebral disc degeneration
Narrative Review on Back Pain, Disc Degeneration, published in Front Bioeng Biotechnol (2022) — summary generated from the PubMed abstract.
- 2022
Front Bioeng Biotechnol39 citations - Level DLaboratory StudyEurope PMC
Uncovering the secretome of mesenchymal stromal cells exposed to healthy, traumatic, and degenerative intervertebral discs: a proteomic analysis
Laboratory Study on Disc Degeneration, Immune Modulation, published in Stem Cell Res Ther (2021) — summary generated from the PubMed abstract.
- 2021
Stem Cell Res Ther47 citations - Level CProspective StudyEurope PMC
microRNA-129-5p shuttled by mesenchymal stem cell-derived extracellular vesicles alleviates intervertebral disc degeneration via blockade of LRG1-mediated p38 MAPK activation
Prospective Study on Disc Degeneration, published in J Tissue Eng (2021) — summary generated from the PubMed abstract.
- 2021
J Tissue Eng45 citations - Level CProspective StudyPubMed
Exosome Degeneration in Mesenchymal Stem Cells Derived from Patients with Type 1 Diabetes Mellitus.
Prospective Study on Type 1 Diabetes, published in Int J Mol Sci (2021) — summary generated from the PubMed abstract.
- 2021
Int J Mol Sci13 citations - Level DAnimal StudyEurope PMC
Exosomes Derived from Bone Mesenchymal Stem Cells Alleviate Compression-Induced Nucleus Pulposus Cell Apoptosis by Inhibiting Oxidative Stress
Animal Study on Disc Degeneration, published in Oxid Med Cell Longev (2021) — summary generated from the PubMed abstract.
- 2021
Oxid Med Cell Longev38 citations - Level DNarrative ReviewEurope PMC
Mechanism of Action of Mesenchymal Stem Cell-Derived Exosomes in the Intervertebral Disc Degeneration Treatment and Bone Repair and Regeneration
Narrative Review on Back Pain, Disc Degeneration, published in Front Cell Dev Biol (2021) — summary generated from the PubMed abstract.
- 2021
Front Cell Dev Biol39 citations - Level DLaboratory StudyPubMed
Adipose mesenchymal stem cells-derived exosomes attenuate retina degeneration of streptozotocin-induced diabetes in rabbits.
Laboratory Study on Systemic / IV, published in J Circ Biomark (2018) — summary generated from the PubMed abstract.
- 2018
J Circ Biomark
In-depth reviewed studies (full Thai translation)
Evidence system- Level ARandomized Controlled Trial
Cell-based versus corticosteroid injections for knee pain in osteoarthritis: a randomized phase 3 trial
A multicentre randomized trial in 480 knee osteoarthritis patients comparing SVF, BMAC and umbilical cord MSCs against corticosteroid injection. At 12 months no cell product outperformed the steroid control.
- 2023
- United States
- n = 480
- Level AMeta-analysis
Intra-articular Injection of Autologous Adipose-Derived Stem Cells or Stromal Vascular Fractions: Are They Effective for Patients With Knee Osteoarthritis? A Systematic Review With Meta-analysis of Randomized Controlled Trials
Pooled five RCTs comparing ADSC/SVF injection with placebo or hyaluronic acid, finding significant pain and function improvement at 6 and 12 months.
- 2023
- South Korea
- Level AMeta-analysis
Rapid-acting pain relief in knee osteoarthritis: autologous-cultured adipose-derived mesenchymal stem cells outperform stromal vascular fraction: a systematic review and meta-analysis
Analysed 31 studies with 1,406 patients: cultured ADMSCs reduced pain from month 3, whereas SVF reached significance only at 12 months.
- 2024
- South Korea
- n = 1406