Research database
SVF Research Library
Search 52,792 real PubMed studies on SVF and adipose-derived stem cells — 22 matching records.
22 results — page 1 of 1
Expanded search to: exosome, extracellular vesicle, secretome
- Level DAnimal StudyPubMed
Extracellular vesicles secreted by adipose-derived stem cells alleviate dedifferentiation and senescence in monolayer-expanded chondrocytes by suppressing interleukin-1β-induced MAPK signaling.
Animal Study on Cartilage Damage, published in Cell Transplant (2026) — summary generated from the PubMed abstract.
- 2026
Cell Transplant - Level DAnimal StudyPubMed
Exosomes secreted from adipose-derived stem cells inhibit M1 macrophage polarization ameliorate chronic endometritis by regulating SIRT2/NLRP3.
Animal Study on Scar, Chronic Inflammation, published in Mol Cell Biochem (2025) — summary generated from the PubMed abstract.
- 2025
Mol Cell Biochem1 citations - Level DAnimal StudyPubMed
Research on the role of exosomes secreted by immortalized adipose-derived mesenchymal stem cells differentiated into pericytes in the repair of high glucose-induced retinal vascular endothelial cell damage.
Animal Study, published in Exp Eye Res (2024) — summary generated from the PubMed abstract.
- 2024
Exp Eye Res6 citations - Level DAnimal StudyPubMed
Exosomes Secreted by Hypoxia-Pre-conditioned Adipose-Derived Mesenchymal Stem Cells Reduce Neuronal Apoptosis in Rats with Spinal Cord Injury.
Animal Study on Spinal Cord Injury, published in J Neurotrauma (2022) — summary generated from the PubMed abstract.
- 2022
J Neurotrauma48 citations - Level CProspective StudyPubMed
Exosomes Secreted from Adipose-Derived Stem Cells Are a Potential Treatment Agent for Immune-Mediated Alopecia.
Prospective Study on Neuroinflammation, Hair Loss, Hair Regeneration, Autoimmune Research, published in J Immunol Res (2022) — summary generated from the PubMed abstract.
- 2022
J Immunol Res43 citations - Level DAnimal StudyPubMed
Adipose-derived mesenchymal stem cell-secreted extracellular vesicles alleviate non-alcoholic fatty liver disease via delivering miR-223-3p.
Animal Study, published in Adipocyte (2022) — summary generated from the PubMed abstract.
- 2022
Adipocyte48 citations - Level CProspective StudyPubMed
Exosomes from Human Omental Adipose-Derived Mesenchymal Stem Cells Secreted into Ascites Promote Peritoneal Metastasis of Epithelial Ovarian Cancer.
Prospective Study, published in Cells (2022) — summary generated from the PubMed abstract.
- 2022
Cells23 citations - Level DLaboratory StudyPubMed
Adipose-derived stem cell-secreted exosomes enhance angiogenesis by promoting macrophage M2 polarization in type 2 diabetic mice with limb ischemia via the JAK/STAT6 pathway.
Laboratory Study, published in Heliyon (2022) — summary generated from the PubMed abstract.
- 2022
Heliyon25 citations - Level DAnimal StudyPubMed
Adipose-derived mesenchymal stem cell-secreted exosome alleviates dextran sulfate sodium-induced acute colitis by Treg cell induction and inflammatory cytokine reduction.
Animal Study on Immune Modulation, Autoimmune Research, published in J Cell Physiol (2021) — summary generated from the PubMed abstract.
- 2021
J Cell Physiol - Level CProspective StudyPubMed
Cartilage Protective and Immunomodulatory Features of Osteoarthritis Synovial Fluid-Treated Adipose-Derived Mesenchymal Stem Cells Secreted Factors and Extracellular Vesicles-Embedded miRNAs.
Prospective Study on Osteoarthritis, Immune Modulation, published in Cells (2021) — summary generated from the PubMed abstract.
- 2021
Cells35 citations - Level DAnimal StudyPubMed
microRNA-26a shuttled by extracellular vesicles secreted from adipose-derived mesenchymal stem cells reduce neuronal damage through KLF9-mediated regulation of TRAF2/KLF2 axis.
Animal Study, published in Adipocyte (2021) — summary generated from the PubMed abstract.
- 2021
Adipocyte16 citations - Level DAnimal StudyPubMed
Enhanced Nerve Regeneration by Exosomes Secreted by Adipose-Derived Stem Cells with or without FK506 Stimulation.
Animal Study, published in Int J Mol Sci (2021) — summary generated from the PubMed abstract.
- 2021
Int J Mol Sci31 citations - Level DLaboratory StudyPubMed
Increased Angiogenesis by Exosomes Secreted by Adipose-Derived Stem Cells upon Lipopolysaccharide Stimulation.
Laboratory Study on Chronic Wound, published in Int J Mol Sci (2021) — summary generated from the PubMed abstract.
- 2021
Int J Mol Sci23 citations - Level DAnimal StudyPubMed
Exosomes Secreted by Adipose-Derived Stem Cells Following FK506 Stimulation Reduce Autophagy of Macrophages in Spine after Nerve Crush Injury.
Animal Study on Neuroinflammation, Chronic Inflammation, published in Int J Mol Sci (2021) — summary generated from the PubMed abstract.
- 2021
Int J Mol Sci18 citations - Level DAnimal StudyPubMed
The Role of Extracellular Vesicles Secreted From Thermal Stress-Induced Adipose-Derived Stem Cells on Bone Regeneration.
Animal Study, published in J Craniofac Surg (2021) — summary generated from the PubMed abstract.
- 2021
J Craniofac Surg3 citations - Level DAnimal StudyPubMed
Exosomes Secreted by Adipose-Derived Mesenchymal Stem Cells Foster Metastasis and Osteosarcoma Proliferation by Increasing COLGALT2 Expression.
Animal Study, published in Front Cell Dev Biol (2020) — summary generated from the PubMed abstract.
- 2020
Front Cell Dev Biol54 citations - Level DAnimal StudyPubMed
Extracellular vesicles-derived miR-150-5p secreted by adipose-derived mesenchymal stem cells inhibits CXCL1 expression to attenuate hepatic fibrosis.
Animal Study on Hip, published in J Cell Mol Med (2020) — summary generated from the PubMed abstract.
- 2020
J Cell Mol Med57 citations - Level DAnimal StudyPubMed
Exosome secreted from adipose-derived stem cells attenuates diabetic nephropathy by promoting autophagy flux and inhibiting apoptosis in podocyte.
Animal Study on Type 1 Diabetes, Type 2 Diabetes, Chronic Kidney Disease, published in Stem Cell Res Ther (2019) — summary generated from the PubMed abstract.
- 2019
Stem Cell Res Ther296 citations - Level DAnimal StudyPubMed
Exosomes Secreted by Adipose-Derived Stem Cells Contribute to Angiogenesis of Brain Microvascular Endothelial Cells Following Oxygen-Glucose Deprivation In Vitro Through MicroRNA-181b/TRPM7 Axis.
Animal Study on Stroke Research, published in J Mol Neurosci (2018) — summary generated from the PubMed abstract.
- 2018
J Mol Neurosci133 citations - Level DLaboratory StudyPubMed
Exosomes secreted by adipose-derived mesenchymal stem cells regulate type I collagen metabolism in fibroblasts from women with stress urinary incontinence.
Laboratory Study, published in Stem Cell Res Ther (2018) — summary generated from the PubMed abstract.
- 2018
Stem Cell Res Ther46 citations - Level DAnimal StudyPubMed
Extracellular Vesicles Secreted by Human Adipose-derived Stem Cells (hASCs) Improve Survival Rate of Rats with Acute Liver Failure by Releasing lncRNA H19.
Animal Study, published in EBioMedicine (2018) — summary generated from the PubMed abstract.
- 2018
EBioMedicine53 citations - Level DAnimal StudyPubMed
Exosomes secreted by mice adipose-derived stem cells after low-level laser irradiation treatment reduce apoptosis of osteocyte induced by hypoxia.
Animal Study with a reported sample of 12, published in Eur Rev Med Pharmacol Sci (2017) — summary generated from the PubMed abstract.
- 2017
- n = 12
Eur Rev Med Pharmacol Sci15 citations
In-depth reviewed studies (full Thai translation)
Evidence system- Level ARandomized Controlled Trial
Cell-based versus corticosteroid injections for knee pain in osteoarthritis: a randomized phase 3 trial
A multicentre randomized trial in 480 knee osteoarthritis patients comparing SVF, BMAC and umbilical cord MSCs against corticosteroid injection. At 12 months no cell product outperformed the steroid control.
- 2023
- United States
- n = 480
- Level AMeta-analysis
Intra-articular Injection of Autologous Adipose-Derived Stem Cells or Stromal Vascular Fractions: Are They Effective for Patients With Knee Osteoarthritis? A Systematic Review With Meta-analysis of Randomized Controlled Trials
Pooled five RCTs comparing ADSC/SVF injection with placebo or hyaluronic acid, finding significant pain and function improvement at 6 and 12 months.
- 2023
- South Korea
- Level AMeta-analysis
Rapid-acting pain relief in knee osteoarthritis: autologous-cultured adipose-derived mesenchymal stem cells outperform stromal vascular fraction: a systematic review and meta-analysis
Analysed 31 studies with 1,406 patients: cultured ADMSCs reduced pain from month 3, whereas SVF reached significance only at 12 months.
- 2024
- South Korea
- n = 1406