Research database
SVF Research Library
Search 52,792 real PubMed studies on SVF and adipose-derived stem cells — 24 matching records.
24 results — page 1 of 1
- Level CProspective StudyPubMed
HDAC1-overexpressing dermal papilla cell-derived extracellular vesicles modulate p53 and Wnt/β-catenin signaling to rescue hair follicle regeneration in androgenetic alopecia.
Prospective Study on Scar, Hair Loss, published in Biomaterials (2026) — summary generated from the PubMed abstract.
- 2026
Biomaterials - Level DAnimal StudyPubMed
Extracellular vesicles secreted by adipose-derived stem cells alleviate dedifferentiation and senescence in monolayer-expanded chondrocytes by suppressing interleukin-1β-induced MAPK signaling.
Animal Study on Cartilage Damage, published in Cell Transplant (2026) — summary generated from the PubMed abstract.
- 2026
Cell Transplant - Level DAnimal StudyPubMed
Extracellular vesicles from SB431542-conditioned human adipose-derived stem cells enhance in vitro and in vivo osteogenesis via a miR-20a-5p-BAMBI-BMP/canonical Wnt signaling axis.
Animal Study, published in Stem Cells Transl Med (2026) — summary generated from the PubMed abstract.
- 2026
Stem Cells Transl Med - Level DNarrative ReviewPubMed
Extracellular Vesicles in Cardiovascular Disease: Intercellular Signaling, Liquid Biopsy Biomarkers, and Therapeutic Translation.
Narrative Review on Systemic / IV, published in Circ Res (2026) — summary generated from the PubMed abstract.
- 2026
Circ Res - Level DAnimal StudyPubMed
Extracellular vesicles from adipose-derived mesenchymal stem cells alleviate acute lung injury via the CBL/AMPK signaling pathway.
Animal Study, published in BMC Biol (2025) — summary generated from the PubMed abstract.
- 2025
BMC Biol4 citations - Level DAnimal StudyPubMed
Small extracellular vesicles from adipose derived stem cells alleviate microglia activation and improve motor deficit of Parkinson's disease via miR-100-5p/DTX3L/STAT1 signaling axis.
Animal Study on Neuroinflammation, Chronic Inflammation, published in Exp Neurol (2025) — summary generated from the PubMed abstract.
- 2025
Exp Neurol3 citations - Level DNarrative ReviewEurope PMC
Therapeutic transplantation of mitochondria and Extracellular Vesicles: Mechanistic insights into mitochondria bioenergetics, redox signaling, and organelle dynamics in preclinical models
Narrative Review, published in Free Radic Biol Med (2025) — summary generated from the PubMed abstract.
- 2025
Free Radic Biol Med12 citations - Level DNarrative ReviewEurope PMC
Extracellular vesicles in metabolic dysfunction-associated steatotic liver disease: From intercellular signaling to clinical translation
Narrative Review, published in World J Hepatol (2025) — summary generated from the PubMed abstract.
- 2025
World J Hepatol3 citations - Level DAnimal StudyEurope PMC
Umbilical Cord Mesenchymal Stem Cell-Derived Extracellular Nanovesicles Alleviated Colitis via Modulating Th17/Treg Balance Through Hsa-miR-27b-3p-Mediated Suppression of PI3K/AKT/STAT3 Signaling Pathway
Animal Study on Chronic Inflammation, Immune Modulation, published in Int J Nanomedicine (2025) — summary generated from the PubMed abstract.
- 2025
Int J Nanomedicine1 citations - Level DAnimal StudyPubMed
Human adipose tissue-derived stem cell extracellular vesicles attenuate ocular hypertension-induced retinal ganglion cell damage by inhibiting microglia- TLR4/MAPK/NF-κB proinflammatory cascade signaling.
Animal Study on Neuroinflammation, Chronic Inflammation, published in Acta Neuropathol Commun (2024) — summary generated from the PubMed abstract.
- 2024
Acta Neuropathol Commun - Level DAnimal StudyPubMed
Extracellular Vesicles Derived from Type 2 Diabetic Mesenchymal Stem Cells Induce Endothelial Mesenchymal Transition under High Glucose Conditions Through the TGFβ/Smad3 Signaling Pathway.
Animal Study on Type 2 Diabetes, Chronic Wound, published in Stem Cells Dev (2024) — summary generated from the PubMed abstract.
- 2024
Stem Cells Dev - Level DAnimal StudyPubMed
Small extracellular vesicles derived from adipose mesenchymal stem cells alleviate intestinal fibrosis by inhibiting the FAK/Akt signaling pathway via MFGE8.
Animal Study on Autoimmune Research, published in J Gastroenterol (2024) — summary generated from the PubMed abstract.
- 2024
J Gastroenterol - Level DAnimal StudyPubMed
Extracellular Vesicles Derived from Adipose-Derived Mesenchymal Stem Cells Alleviate Apoptosis and Oxidative Stress of Retinal Pigment Epithelial Cells Through Activation of Nrf2 Signaling Pathway.
Animal Study, published in J Ocul Pharmacol Ther (2024) — summary generated from the PubMed abstract.
- 2024
J Ocul Pharmacol Ther4 citations - Level DNarrative ReviewEurope PMC
Hitting the target: cell signaling pathways modulation by extracellular vesicles
Narrative Review on Face & Skin, Hip, published in Extracell Vesicles Circ Nucl Acids (2024) — summary generated from the PubMed abstract.
- 2024
Extracell Vesicles Circ Nucl Acids12 citations - Level DAnimal StudyPubMed
Adipose mesenchymal stem cell-derived extracellular vesicles alleviate renal fibrosis by reducing epithelial-mesenchymal transition via the FOXS1/Wnt/β-catenin signaling pathway.
Animal Study on Chronic Kidney Disease, published in Int Immunopharmacol (2024) — summary generated from the PubMed abstract.
- 2024
Int Immunopharmacol - Level DAnimal StudyPubMed
Extracellular vesicles of ADSCs inhibit ischemic stroke-induced pyroptosis through Gbp3 regulation: A role for the NLRP3/GSDMD signaling pathway.
Animal Study on Stroke Research, Chronic Inflammation, published in Int Immunopharmacol (2024) — summary generated from the PubMed abstract.
- 2024
Int Immunopharmacol3 citations - Level CProspective StudyPubMed
Peritoneal adipose stem cell-derived extracellular vesicles mediate the regulation of ovarian cancer cell proliferation and migration through EGFR-NF-κB signaling.
Prospective Study, published in Genes Dis (2024) — summary generated from the PubMed abstract.
- 2024
Genes Dis7 citations - Level DAnimal StudyPubMed
Hypertonicity induces mitochondrial extracellular vesicles (MEVs) that activate TNF-α and β-catenin signaling to promote adipocyte dedifferentiation.
Animal Study, published in Stem Cell Res Ther (2023) — summary generated from the PubMed abstract.
- 2023
Stem Cell Res Ther10 citations - Level DNarrative ReviewEurope PMC
Extracellular Vesicles in Redox Signaling and Metabolic Regulation in Chronic Kidney Disease
Narrative Review on Chronic Kidney Disease, published in Antioxidants (Basel) (2022) — summary generated from the PubMed abstract.
- 2022
Antioxidants (Basel)18 citations - Level DAnimal StudyPubMed
Mesenchymal Stem Cells and Extracellular Vesicles Derived from Canine Adipose Tissue Ameliorates Inflammation, Skin Barrier Function and Pruritus by Reducing JAK/STAT Signaling in Atopic Dermatitis.
Animal Study on Chronic Inflammation, Immune Modulation, published in Int J Mol Sci (2022) — summary generated from the PubMed abstract.
- 2022
Int J Mol Sci - Level DNarrative ReviewEurope PMC
Regulation of Nrf2 signaling pathway in heart failure: Role of extracellular vesicles and non-coding RNAs
Narrative Review on Cardiovascular Disease, published in Free Radic Biol Med (2021) — summary generated from the PubMed abstract.
- 2021
Free Radic Biol Med51 citations - Level DLaboratory StudyEurope PMC
miR-330-5p in Small Extracellular Vesicles Derived From Plastrum testudinis-Preconditioned Bone Mesenchymal Stem Cells Attenuates Osteogenesis by Modulating Wnt/β-Catenin Signaling
Laboratory Study, published in Front Mol Biosci (2021) — summary generated from the PubMed abstract.
- 2021
Front Mol Biosci3 citations - Level DAnimal StudyPubMed
Extracellular Vesicles from Adipose-Derived Stem Cells Promote Diabetic Wound Healing via the PI3K-AKT-mTOR-HIF-1α Signaling Pathway.
Animal Study on Diabetic Foot, Chronic Wound, published in Tissue Eng Regen Med (2021) — summary generated from the PubMed abstract.
- 2021
Tissue Eng Regen Med46 citations - Level DNarrative ReviewEurope PMC
Extracellular vesicles as signaling mediators in type 2 diabetes mellitus
Narrative Review on Type 2 Diabetes, published in Am J Physiol Cell Physiol (2020) — summary generated from the PubMed abstract.
- 2020
Am J Physiol Cell Physiol66 citations
In-depth reviewed studies (full Thai translation)
Evidence system- Level ARandomized Controlled Trial
Cell-based versus corticosteroid injections for knee pain in osteoarthritis: a randomized phase 3 trial
A multicentre randomized trial in 480 knee osteoarthritis patients comparing SVF, BMAC and umbilical cord MSCs against corticosteroid injection. At 12 months no cell product outperformed the steroid control.
- 2023
- United States
- n = 480
- Level AMeta-analysis
Intra-articular Injection of Autologous Adipose-Derived Stem Cells or Stromal Vascular Fractions: Are They Effective for Patients With Knee Osteoarthritis? A Systematic Review With Meta-analysis of Randomized Controlled Trials
Pooled five RCTs comparing ADSC/SVF injection with placebo or hyaluronic acid, finding significant pain and function improvement at 6 and 12 months.
- 2023
- South Korea
- Level AMeta-analysis
Rapid-acting pain relief in knee osteoarthritis: autologous-cultured adipose-derived mesenchymal stem cells outperform stromal vascular fraction: a systematic review and meta-analysis
Analysed 31 studies with 1,406 patients: cultured ADMSCs reduced pain from month 3, whereas SVF reached significance only at 12 months.
- 2024
- South Korea
- n = 1406