Research database
SVF Research Library
Search 52,792 real PubMed studies on SVF and adipose-derived stem cells — 21 matching records.
21 results — page 1 of 1
- Level BRandomized Controlled TrialPubMed
Enhancing Lumbar Spinal Fusion Using Hypoxia Preconditioned Culture-Expanded Adipose-Derived Mesenchymal Stem Cells: Evidence From a Rat Posterolateral Lumbar Spinal Fusion Model.
Randomized Controlled Trial on Back & Spine, published in Neurosurgery (2026) — summary generated from the PubMed abstract.
- 2026
Neurosurgery - Level CProspective StudyPubMed
Hypoxia-preconditioned adipose-derived mesenchymal stem cells-derived exosomes transferring H19 obstruct neutrophil extracellular traps formation via HOXA5-mediated inactivation of TLR4/NF-κB/NLRP3 inflammatory signaling
Prospective Study on Diabetic Foot, Chronic Wound, published in J Diabetes Investig (2026) — summary generated from the PubMed abstract.
- 2026
J Diabetes Investig - Level DAnimal StudyEurope PMC
Extracellular vesicles derived from clonal mesenchymal stromal cells preconditioned by indirect hypoxia modulate immune responses in diabetic mice more effectively than directly preconditioned vesicles
Animal Study on Type 1 Diabetes, Chronic Inflammation, Immune Modulation, published in Stem Cell Res Ther (2025) — summary generated from the PubMed abstract.
- 2025
Stem Cell Res Ther2 citations - Level DAnimal StudyPubMed
Extracellular vesicles from hypoxia-preconditioned mesenchymal stem cells preserve mitochondrial functions and redox homeostasis in ischemia-reperfusion-induced acute kidney injury.
Animal Study on Acute Kidney Injury, published in Biochim Biophys Acta Gen Subj (2025) — summary generated from the PubMed abstract.
- 2025
Biochim Biophys Acta Gen Subj - Level DLaboratory StudyPubMed
Apoptotic extracellular vesicles derived from hypoxia-preconditioned mesenchymal stem cells within a modified gelatine hydrogel promote osteochondral regeneration by enhancing stem cell activity and regulating immunity.
Laboratory Study on Cartilage Damage, Immune Modulation, published in J Nanobiotechnology (2024) — summary generated from the PubMed abstract.
- 2024
J Nanobiotechnology41 citations - Level DAnimal StudyPubMed
Exosomes Secreted by Hypoxia-Pre-conditioned Adipose-Derived Mesenchymal Stem Cells Reduce Neuronal Apoptosis in Rats with Spinal Cord Injury.
Animal Study on Spinal Cord Injury, published in J Neurotrauma (2022) — summary generated from the PubMed abstract.
- 2022
J Neurotrauma48 citations - Level DAnimal StudyPubMed
Extracellular vesicles from hypoxia-preconditioned mesenchymal stem cells alleviates myocardial injury by targeting thioredoxin-interacting protein-mediated hypoxia-inducible factor-1α pathway.
Animal Study on Cardiovascular Disease, published in World J Stem Cells (2022) — summary generated from the PubMed abstract.
- 2022
World J Stem Cells24 citations - Level DLaboratory StudyPubMed
Comparison Study on the Effect of Mesenchymal Stem Cells-Conditioned Medium Derived from Adipose and Wharton's Jelly on Versican Gene Expression in Hypoxia.
Laboratory Study on Face & Skin, published in Iran Biomed J (2022) — summary generated from the PubMed abstract.
- 2022
Iran Biomed J - Level DLaboratory StudyPubMed
Extracellular Vesicles Derived From Hypoxia-Conditioned Adipose-Derived Mesenchymal Stem Cells Enhance Lymphangiogenesis.
Laboratory Study, published in Cell Transplant (2022) — summary generated from the PubMed abstract.
- 2022
Cell Transplant9 citations - Level DLaboratory StudyEurope PMC
Exosomal HMGB1 derived from hypoxia-conditioned bone marrow mesenchymal stem cells increases angiogenesis via the JNK/HIF-1α pathway
Laboratory Study, published in FEBS Open Bio (2021) — summary generated from the PubMed abstract.
- 2021
FEBS Open Bio58 citations - Level DAnimal StudyEurope PMC
Exosomes Secreted from Hypoxia-Preconditioned Mesenchymal Stem Cells Prevent Steroid-Induced Osteonecrosis of the Femoral Head by Promoting Angiogenesis in Rats
Animal Study on Hip, published in Biomed Res Int (2021) — summary generated from the PubMed abstract.
- 2021
Biomed Res Int45 citations - Level DAnimal StudyPubMed
Extracellular vesicle-derived miR-511-3p from hypoxia preconditioned adipose mesenchymal stem cells ameliorates spinal cord injury through the TRAF6/S1P axis.
Animal Study on Spinal Cord Injury, published in Brain Res Bull (2021) — summary generated from the PubMed abstract.
- 2021
Brain Res Bull19 citations - Level DAnimal StudyPubMed
Effect of Hypoxia Preconditioned Adipose-Derived Mesenchymal Stem Cell Conditioned Medium on Cerulein-Induced Acute Pancreatitis in Mice.
Animal Study, published in Adv Pharm Bull (2020) — summary generated from the PubMed abstract.
- 2020
Adv Pharm Bull19 citations - Level DAnimal StudyPubMed
[Effects of hypoxia-pretreated rat adipose-derived mesenchymal stem cells conditioned medium on wound healing of rats with full-thickness defects].
Animal Study on Chronic Wound, published in Zhonghua Shao Shang Za Zhi (2020) — summary generated from the PubMed abstract.
- 2020
Zhonghua Shao Shang Za Zhi6 citations - Level DLaboratory StudyPubMed
Hypoxia Conditioned Mesenchymal Stem Cell-Derived Extracellular Vesicles Induce Increased Vascular Tube Formation in vitro .
Laboratory Study on Face & Skin, published in Front Bioeng Biotechnol (2019) — summary generated from the PubMed abstract.
- 2019
Front Bioeng Biotechnol - Level DAnimal StudyPubMed
Co-transplantation of exosomes derived from hypoxia-preconditioned adipose mesenchymal stem cells promotes neovascularization and graft survival in fat grafting.
Animal Study, published in Biochem Biophys Res Commun (2018) — summary generated from the PubMed abstract.
- 2018
Biochem Biophys Res Commun125 citations - Level DAnimal StudyPubMed
Secretome from hypoxia-conditioned adipose-derived mesenchymal stem cells promotes the healing of gastric mucosal injury in a rodent model.
Animal Study on Chronic Wound, published in Biochim Biophys Acta Mol Basis Dis (2017) — summary generated from the PubMed abstract.
- 2017
Biochim Biophys Acta Mol Basis Dis49 citations - Level CProspective StudyPubMed
Hypoxia-Induced Damage in Human Islets Is Reduced With the Use of Mesenchymal Stem Cell-Preconditioned Medium.
Prospective Study, published in Transplant Proc (2017) — summary generated from the PubMed abstract.
- 2017
Transplant Proc - Level DAnimal StudyPubMed
Concentrated Hypoxia-Preconditioned Adipose Mesenchymal Stem Cell-Conditioned Medium Improves Wounds Healing in Full-Thickness Skin Defect Model.
Animal Study on Chronic Wound, published in Int Sch Res Notices (2014) — summary generated from the PubMed abstract.
- 2014
Int Sch Res Notices13 citations - Level DLaboratory StudyPubMed
Hypoxia preconditioned human adipose derived mesenchymal stem cells enhance angiogenic potential via secretion of increased VEGF and bFGF.
Laboratory Study, published in Cell Biol Int (2013) — summary generated from the PubMed abstract.
- 2013
Cell Biol Int128 citations - Level DAnimal StudyPubMed
Hypoxia-preconditioned adipose tissue-derived mesenchymal stem cell increase the survival and gene expression of engineered neural stem cells in a spinal cord injury model.
Animal Study on Spinal Cord Injury, published in Neurosci Lett (2010) — summary generated from the PubMed abstract.
- 2010
Neurosci Lett
In-depth reviewed studies (full Thai translation)
Evidence system- Level ARandomized Controlled Trial
Cell-based versus corticosteroid injections for knee pain in osteoarthritis: a randomized phase 3 trial
A multicentre randomized trial in 480 knee osteoarthritis patients comparing SVF, BMAC and umbilical cord MSCs against corticosteroid injection. At 12 months no cell product outperformed the steroid control.
- 2023
- United States
- n = 480
- Level AMeta-analysis
Intra-articular Injection of Autologous Adipose-Derived Stem Cells or Stromal Vascular Fractions: Are They Effective for Patients With Knee Osteoarthritis? A Systematic Review With Meta-analysis of Randomized Controlled Trials
Pooled five RCTs comparing ADSC/SVF injection with placebo or hyaluronic acid, finding significant pain and function improvement at 6 and 12 months.
- 2023
- South Korea
- Level AMeta-analysis
Rapid-acting pain relief in knee osteoarthritis: autologous-cultured adipose-derived mesenchymal stem cells outperform stromal vascular fraction: a systematic review and meta-analysis
Analysed 31 studies with 1,406 patients: cultured ADMSCs reduced pain from month 3, whereas SVF reached significance only at 12 months.
- 2024
- South Korea
- n = 1406