Research database
SVF Research Library
Search 52,792 real PubMed studies on SVF and adipose-derived stem cells — 45 matching records.
45 results — page 1 of 2
- Level ASystematic ReviewEurope PMC
Pro-tumorigenic effects and therapeutic implications of mesenchymal stem cell-derived exosomes under hypoxic conditions: a systematic review
Systematic Review, published in Discov Oncol (2026) — summary generated from the PubMed abstract.
- 2026
Discov Oncol - Level DAnimal StudyPubMed
Hypoxic preconditioning drives metabolic reprogramming to increase the therapeutic efficacy of adipose mesenchymal stem cells in diabetic wounds.
Animal Study on Diabetic Foot, Chronic Wound, published in J Transl Med (2026) — summary generated from the PubMed abstract.
- 2026
J Transl Med - Level CProspective StudyPubMed
Hypoxic human adipose mesenchymal stem cells-derived extracellular vesicles induce P311 expression and inhibit activation and injury of human brain microvascular endothelial cells.
Prospective Study on Face & Skin, published in Clin Hemorheol Microcirc (2025) — summary generated from the PubMed abstract.
- 2025
Clin Hemorheol Microcirc - Level DAnimal StudyEurope PMC
Bone marrow mesenchymal stem cells alleviate neurological dysfunction by reducing autophagy damage via downregulation of SYNPO2 in neonatal hypoxic-ischemic encephalopathy rats
Animal Study, published in Cell Death Dis (2025) — summary generated from the PubMed abstract.
- 2025
Cell Death Dis6 citations - Level DAnimal StudyPubMed
Administration of hypoxic pretreated adipose-derived mesenchymal stem cell exosomes promotes spinal cord repair after injury via delivery of circ-Astn1 and activation of autophagy.
Animal Study on Spinal Cord Injury, published in Int Immunopharmacol (2025) — summary generated from the PubMed abstract.
- 2025
Int Immunopharmacol3 citations - Level DAnimal StudyEurope PMC
Roles of TGF-β in the therapeutic potential of hypoxic mesenchymal stem cells for treating osteoarthritis in a Rabbit model
Animal Study on Osteoarthritis, Ligament Injury, published in J Orthop Surg Res (2025) — summary generated from the PubMed abstract.
- 2025
J Orthop Surg Res - Level DLaboratory StudyPubMed
Effects of hypoxic and photobiomodulation preconditioning on mesenchymal stem cell-derived exosomes: an in vitro study with an osteogenic potential approach.
Laboratory Study on Immune Modulation, published in Photochem Photobiol Sci (2025) — summary generated from the PubMed abstract.
- 2025
Photochem Photobiol Sci - Level DAnimal StudyEurope PMC
Hypoxic Bone Mesenchymal Stem Cell-Derived Exosomes Direct Schwann Cells Proliferation, Migration, and Paracrine to Accelerate Facial Nerve Regeneration via circRNA_Nkd2/miR-214-3p/MED19 Axis
Animal Study on Face & Skin, published in Int J Nanomedicine (2024) — summary generated from the PubMed abstract.
- 2024
Int J Nanomedicine20 citations - Level DAnimal StudyEurope PMC
Role of Hypoxic Secretome from Mesenchymal Stem Cells in Enhancing Tissue Repair: Regulatory Effects on HIF-1α, VEGF, and Fibroblast in a Sphincterotomy Rat Model
Animal Study on Chronic Wound, published in J Inflamm Res (2024) — summary generated from the PubMed abstract.
- 2024
J Inflamm Res4 citations - Level DLaboratory StudyPubMed
Hypoxic Stress Induces Complement-Mediated Lysis of Mesenchymal Stem Cells by Downregulating Factor H and CD59.
Laboratory Study, published in Tissue Eng Regen Med (2024) — summary generated from the PubMed abstract.
- 2024
Tissue Eng Regen Med - Level DAnimal StudyEurope PMC
Dental pulp mesenchymal stem cell (DPSCs)-derived soluble factors, produced under hypoxic conditions, support angiogenesis via endothelial cell activation and generation of M2-like macrophages
Animal Study, published in J Biomed Sci (2024) — summary generated from the PubMed abstract.
- 2024
J Biomed Sci14 citations - Level DAnimal StudyPubMed
Gelatin methacryloyl (GelMA) loaded with concentrated hypoxic pretreated adipose-derived mesenchymal stem cells(ADSCs) conditioned medium promotes wound healing and vascular regeneration in aged skin.
Animal Study on Chronic Wound, published in Biomater Res (2023) — summary generated from the PubMed abstract.
- 2023
Biomater Res81 citations - Level DAnimal StudyPubMed
Adipose mesenchymal stem cell-derived soluble factors, produced under hypoxic condition, efficiently support in vivo angiogenesis.
Animal Study, published in Cell Death Discov (2023) — summary generated from the PubMed abstract.
- 2023
Cell Death Discov25 citations - Level DLaboratory StudyEurope PMC
Hypoxic mesenchymal stem cell-derived exosomes promote the survival of skin flaps after ischaemia-reperfusion injury via mTOR/ULK1/FUNDC1 pathways
Laboratory Study, published in J Nanobiotechnology (2023) — summary generated from the PubMed abstract.
- 2023
J Nanobiotechnology33 citations - Level DAnimal StudyEurope PMC
Synergistic effect of chitosan-alginate composite hydrogel enriched with ascorbic acid and alpha-tocopherol under hypoxic conditions on the behavior of mesenchymal stem cells for wound healing
Animal Study on Chronic Wound, published in Stem Cell Res Ther (2023) — summary generated from the PubMed abstract.
- 2023
Stem Cell Res Ther19 citations - Level BClinical TrialPubMed
Adipose-Derived Mesenchymal Stem Cells Protect Endothelial Cells from Hypoxic Injury by Suppressing Terminal UPR In Vivo and In Vitro.
Clinical Trial on Peripheral Artery Disease, published in Int J Mol Sci (2023) — summary generated from the PubMed abstract.
- 2023
Int J Mol Sci5 citations - Level DLaboratory StudyPubMed
Adipose-derived mesenchymal stem cells with hypoxic preconditioning improve tenogenic differentiation.
Laboratory Study on Tendon Injury, published in J Orthop Surg Res (2022) — summary generated from the PubMed abstract.
- 2022
J Orthop Surg Res13 citations - Level CProspective StudyPubMed
Small extracellular vesicles of hypoxic endothelial cells regulate the therapeutic potential of adipose-derived mesenchymal stem cells via miR-486-5p/PTEN in a limb ischemia model.
Prospective Study on Peripheral Artery Disease, published in J Nanobiotechnology (2022) — summary generated from the PubMed abstract.
- 2022
J Nanobiotechnology15 citations - Level DLaboratory StudyPubMed
Regenerative Effect of Adipose Derived Mesenchymal Stem Cells on Ganglion Cells in the Hypoxic Organotypic Retina Culture.
Laboratory Study, published in Int J Stem Cells (2022) — summary generated from the PubMed abstract.
- 2022
Int J Stem Cells6 citations - Level DAnimal StudyEurope PMC
Hypoxic culture of umbilical cord mesenchymal stem cell-derived sEVs prompts peripheral nerve injury repair
Animal Study, published in Front Cell Neurosci (2022) — summary generated from the PubMed abstract.
- 2022
Front Cell Neurosci8 citations - Level CProspective StudyEurope PMC
Donor heart preservation with hypoxic-conditioned medium-derived from bone marrow mesenchymal stem cells improves cardiac function in a heart transplantation model
Prospective Study on Cardiovascular Disease, published in Stem Cell Res Ther (2021) — summary generated from the PubMed abstract.
- 2021
Stem Cell Res Ther17 citations - Level DLaboratory StudyEurope PMC
Optimal Hypoxic Preconditioning of Human Embryonic Stem Cell-Derived Mesenchymal Stem Cells (hES-MSCs) and Their Characteristics
Laboratory Study, published in Int J Stem Cells (2021) — summary generated from the PubMed abstract.
- 2021
Int J Stem Cells11 citations - Level CProspective StudyPubMed
Hypoxic preconditioning induces epigenetic changes and modifies swine mesenchymal stem cell angiogenesis and senescence in experimental atherosclerotic renal artery stenosis.
Prospective Study on Chronic Kidney Disease, published in Stem Cell Res Ther (2021) — summary generated from the PubMed abstract.
- 2021
Stem Cell Res Ther - Level DAnimal StudyPubMed
Adipose Derived Mesenchymal Stem Cells from a Hypoxic Culture Reduce Cartilage Damage.
Animal Study on Cartilage Damage, published in Stem Cell Rev Rep (2021) — summary generated from the PubMed abstract.
- 2021
Stem Cell Rev Rep12 citations
In-depth reviewed studies (full Thai translation)
Evidence system- Level ARandomized Controlled Trial
Cell-based versus corticosteroid injections for knee pain in osteoarthritis: a randomized phase 3 trial
A multicentre randomized trial in 480 knee osteoarthritis patients comparing SVF, BMAC and umbilical cord MSCs against corticosteroid injection. At 12 months no cell product outperformed the steroid control.
- 2023
- United States
- n = 480
- Level AMeta-analysis
Intra-articular Injection of Autologous Adipose-Derived Stem Cells or Stromal Vascular Fractions: Are They Effective for Patients With Knee Osteoarthritis? A Systematic Review With Meta-analysis of Randomized Controlled Trials
Pooled five RCTs comparing ADSC/SVF injection with placebo or hyaluronic acid, finding significant pain and function improvement at 6 and 12 months.
- 2023
- South Korea
- Level AMeta-analysis
Rapid-acting pain relief in knee osteoarthritis: autologous-cultured adipose-derived mesenchymal stem cells outperform stromal vascular fraction: a systematic review and meta-analysis
Analysed 31 studies with 1,406 patients: cultured ADMSCs reduced pain from month 3, whereas SVF reached significance only at 12 months.
- 2024
- South Korea
- n = 1406