Research database
SVF Research Library
Search 52,792 real PubMed studies on SVF and adipose-derived stem cells — 94 matching records.
94 results — page 1 of 4
- Level DLaboratory StudyPubMed
Intra-articular and intra-osseous expanded adipose-derived stromal cell injections for knee osteoarthritis-related bone marrow lesions yield promising outcomes: Preliminary results in 16 athletes.
Laboratory Study on Knee Osteoarthritis, Osteoarthritis, published in J Exp Orthop (2026) — summary generated from the PubMed abstract.
- 2026
J Exp Orthop - Level BRandomized Controlled TrialEurope PMC
Safety and Efficacy of Intra-articular Cell-Free Fat Extract Injection in Patients With Symptomatic Knee Osteoarthritis
Randomized Controlled Trial with a reported sample of 24 on Knee Osteoarthritis, Osteoarthritis, published in Orthop J Sports Med (2026) — summary generated from the PubMed abstract.
- 2026
- n = 24
Orthop J Sports Med - Level BRandomized Controlled TrialPubMed
Intra-articular allogeneic adipose-derived mesenchymal stromal cell injections for stage III knee osteoarthritis: a double-blind placebo-controlled trial with 60-month follow-up.
Randomized Controlled Trial with a reported sample of 29 on Knee Osteoarthritis, Osteoarthritis, Cartilage Damage, published in Stem Cells Transl Med (2026) — summary generated from the PubMed abstract.
- 2026
- n = 29
Stem Cells Transl Med - Level BRandomized Controlled TrialEurope PMC
Randomized clinical trial comparing intra-articular injection of bone marrow aspirate clot and bone marrow aspirate concentrate in grade 3 and 4 knee osteoarthritis
Randomized Controlled Trial on Knee Osteoarthritis, Osteoarthritis, published in Stem Cell Res Ther (2026) — summary generated from the PubMed abstract.
- 2026
Stem Cell Res Ther - Level BClinical TrialPubMed
Factors affecting outcomes of intra-articular injection of autologous, culture-expanded, adipose-derived mesenchymal stem cells in knee osteoarthritis.
Clinical Trial with a reported sample of 104 on Knee Osteoarthritis, Osteoarthritis, published in Stem Cells Transl Med (2026) — summary generated from the PubMed abstract.
- 2026
- n = 104
Stem Cells Transl Med - Level ASystematic ReviewPubMed
Comparative Efficacy and Safety of Intra-Articular Adipose-Derived, Bone Marrow-Derived, and Peripheral Blood-Derived Stem Cell Injections for Knee Osteoarthritis: A Systematic Review.
Systematic Review with a reported sample of 1247 on Knee Osteoarthritis, Osteoarthritis, published in Bioengineering (Basel) (2026) — summary generated from the PubMed abstract.
- 2026
- n = 1247
Bioengineering (Basel) - Level DNarrative ReviewEurope PMC
Intra-Articular Injection of Stem Cells for the Regeneration of Knee Joint Cartilage: a Therapeutic Option for Knee Osteoarthritis - a Narrative Review
Narrative Review on Knee Osteoarthritis, Osteoarthritis, Cartilage Damage, published in Biomol Ther (Seoul) (2025) — summary generated from the PubMed abstract.
- 2025
Biomol Ther (Seoul)4 citations - Level BClinical TrialPubMed
Arthroscopic debridement followed by intra-articular injection of micro-fragmented adipose tissue in patients affected by knee osteoarthritis: Clinical results up to 48 months from a prospective clinical study.
Clinical Trial with a reported sample of 39 on Knee Osteoarthritis, Osteoarthritis, published in J Exp Orthop (2025) — summary generated from the PubMed abstract.
- 2025
- n = 39
J Exp Orthop6 citations - Level DAnimal StudyPubMed
Therapeutic efficacy of intra-articular injection of human adipose-derived mesenchymal stem cells in a sheep model of knee osteoarthritis.
Animal Study on Knee Osteoarthritis, Osteoarthritis, Cartilage Damage, Ligament Injury, published in Stem Cell Res Ther (2025) — summary generated from the PubMed abstract.
- 2025
Stem Cell Res Ther2 citations - Level AMeta-analysisEurope PMC
Comparison of Different Molecular Weights of Intra-Articular Hyaluronic Acid Injections for Knee Osteoarthritis: A Level I Bayesian Network Meta-Analysis
Meta-analysis with a reported sample of 9822 on Knee Osteoarthritis, Osteoarthritis, published in Biomedicines (2025) — summary generated from the PubMed abstract.
- 2025
- n = 9822
Biomedicines14 citations - Level AMeta-analysisPubMed
Intra-articular Stromal Vascular Fraction and Mesenchymal Stem Cell Injections Show Variable Efficacy and Higher Potential Complications Compared to Corticosteroid and Hyaluronic Acid in Treatment of Knee Osteoarthritis:
Meta-analysis with a reported sample of 671 on Knee Osteoarthritis, Osteoarthritis, published in Arthroscopy (2025) — summary generated from the PubMed abstract.
- 2025
- n = 671
Arthroscopy4 citations - Level DNarrative ReviewPubMed
Comparison of short-term clinical outcomes of intra-articular injection of micro-fragmented adipose tissue and stromal vascular fraction cells for knee osteoarthritis treatment: A retrospective single-center cohort study
Narrative Review on Knee Osteoarthritis, Osteoarthritis, Autoimmune Research, published in Regen Ther (2025) — summary generated from the PubMed abstract.
- 2025
Regen Ther5 citations - Level DLaboratory StudyEurope PMC
Efficacy of intra-articular injections for the treatment of osteoarthritis: A narrative review
Laboratory Study on Knee Osteoarthritis, Osteoarthritis, published in Osteoarthr Cartil Open (2025) — summary generated from the PubMed abstract.
- 2025
Osteoarthr Cartil Open7 citations - Level BRandomized Controlled TrialPubMed
Effect of intra-articular adipose-derived mesenchymal stromal cell versus placebo injection on pain and function in patients with knee osteoarthritis: the ADIPOA2 phase 2b randomised clinical trial.
Randomized Controlled Trial with a reported sample of 26 on Knee Osteoarthritis, Osteoarthritis, published in Ann Rheum Dis (2025) — summary generated from the PubMed abstract.
- 2025
- n = 26
Ann Rheum Dis - Level AMeta-analysisEurope PMC
Efficacy of a single intra-articular injection of mesenchymal stem cells for knee osteoarthritis: a dose-focused meta-analysis of randomized controlled trials
Meta-analysis with a reported sample of 300 on Knee Osteoarthritis, Osteoarthritis, published in J Orthop Surg Res (2025) — summary generated from the PubMed abstract.
- 2025
- n = 300
J Orthop Surg Res - Level CProspective StudyPubMed
A single intra-articular stromal vascular fraction with platelet-rich plasma injection yields superior clinical outcomes than a hyaluronic acid injection in patients with knee osteoarthritis: A prospective comparative st
Prospective Study with a reported sample of 108 on Knee Osteoarthritis, Osteoarthritis, published in Knee Surg Sports Traumatol Arthrosc (2025) — summary generated from the PubMed abstract.
- 2025
- n = 108
Knee Surg Sports Traumatol Arthrosc1 citations - Level AMeta-analysisPubMed
Microfragmented Adipose Tissue as an Alternative to Platelet-Rich Plasma for Intra-articular Injection in Knee Osteoarthritis: A Systematic Review and Meta-analysis of Randomized Controlled Trials.
Meta-analysis on Knee Osteoarthritis, Osteoarthritis, published in Am J Sports Med (2025) — summary generated from the PubMed abstract.
- 2025
Am J Sports Med - Level AMeta-analysisEurope PMC
Placebo response to intra-articular injections in knee osteoarthritis: magnitude, evolution over time, and influencing factors. A systematic review and meta-analysis with meta-regression
Meta-analysis with a reported sample of 895 on Knee Osteoarthritis, Osteoarthritis, published in EFORT Open Rev (2025) — summary generated from the PubMed abstract.
- 2025
- n = 895
EFORT Open Rev2 citations - Level CProspective StudyPubMed
Bone Marrow Aspirate Concentrate (BMAC) Versus Adipose-Derived Stem Cells (ADSCs) Intra-articular Injection Therapeutic Efficacy in Knee OA Correlated to Their Mesenchymal Stem Cell (MSC) Cellularity: An Exploratory Comp
Prospective Study with a reported sample of 60 on Knee Osteoarthritis, Osteoarthritis, Meniscus Injury, published in Indian J Orthop (2025) — summary generated from the PubMed abstract.
- 2025
- n = 60
Indian J Orthop1 citations - Level BClinical TrialPubMed
Timing of intra-articular injection of adipose-derived mesenchymal stem cells affects cartilage integrity and IL-18 expression in spontaneous osteoarthritis: A preclinical study.
Clinical Trial on Knee Osteoarthritis, Osteoarthritis, Cartilage Damage, published in Int Immunopharmacol (2025) — summary generated from the PubMed abstract.
- 2025
Int Immunopharmacol - Level DAnimal StudyPubMed
Intra-Articular Injection of Adipose-Derived-MSC Exosomes and Hyaluronic Acid in Sheep Knee Osteoarthritic Models Enhances Hyaline Cartilage Regeneration.
Animal Study on Knee Osteoarthritis, Osteoarthritis, Cartilage Damage, published in Biomedicines (2025) — summary generated from the PubMed abstract.
- 2025
Biomedicines - Level BRandomized Controlled TrialEurope PMC
Intra-articular injection of umbilical cord-derived mesenchymal stem cells is safe and effective for moderate to severe knee osteoarthritis with synovitis: a double‑blinded and randomized controlled trial
Randomized Controlled Trial with a reported sample of 55 on Knee Osteoarthritis, Osteoarthritis, published in BMC Musculoskelet Disord (2025) — summary generated from the PubMed abstract.
- 2025
- n = 55
BMC Musculoskelet Disord - Level BClinical TrialPubMed
Safety and Tolerability of Intra-Articular Injection of Adipose-Derived Mesenchymal Stem Cells GXCPC1 in 11 Subjects With Knee Osteoarthritis: A Nonrandomized Pilot Study Without a Control Arm.
Clinical Trial on Knee Osteoarthritis, Osteoarthritis, published in Cell Transplant (2024) — summary generated from the PubMed abstract.
- 2024
Cell Transplant13 citations - Level CProspective StudyEurope PMC
Intra-articular injection of bone marrow aspirate concentrate (mesenchymal stem cells) in KL grade III and IV knee osteoarthritis: 4 year results of 37 knees
Prospective Study with a reported sample of 37 on Knee Osteoarthritis, Osteoarthritis, published in Sci Rep (2024) — summary generated from the PubMed abstract.
- 2024
- n = 37
Sci Rep23 citations
In-depth reviewed studies (full Thai translation)
Evidence system- Level ARandomized Controlled Trial
Cell-based versus corticosteroid injections for knee pain in osteoarthritis: a randomized phase 3 trial
A multicentre randomized trial in 480 knee osteoarthritis patients comparing SVF, BMAC and umbilical cord MSCs against corticosteroid injection. At 12 months no cell product outperformed the steroid control.
- 2023
- United States
- n = 480
- Level AMeta-analysis
Intra-articular Injection of Autologous Adipose-Derived Stem Cells or Stromal Vascular Fractions: Are They Effective for Patients With Knee Osteoarthritis? A Systematic Review With Meta-analysis of Randomized Controlled Trials
Pooled five RCTs comparing ADSC/SVF injection with placebo or hyaluronic acid, finding significant pain and function improvement at 6 and 12 months.
- 2023
- South Korea
- Level AMeta-analysis
Rapid-acting pain relief in knee osteoarthritis: autologous-cultured adipose-derived mesenchymal stem cells outperform stromal vascular fraction: a systematic review and meta-analysis
Analysed 31 studies with 1,406 patients: cultured ADMSCs reduced pain from month 3, whereas SVF reached significance only at 12 months.
- 2024
- South Korea
- n = 1406