Research database
SVF Research Library
Search 52,792 real PubMed studies on SVF and adipose-derived stem cells — 27 matching records.
27 results — page 1 of 2
- Level DLaboratory StudyPubMed
Aberrantly expressed long noncoding RNAs in adipose-derived mesenchymal stem cells differentiation to nucleus pulposus-like cells.
Laboratory Study on Disc Degeneration, published in Sci Rep (2026) — summary generated from the PubMed abstract.
- 2026
Sci Rep - Level DAnimal StudyPubMed
Comparative Study of Mesenchymal Stem Cell Identity and Chondrogenic Differentiation Capacity of Human Nucleus Pulposus, Adipose and Bone Marrow Tissues Derived Mesenchymal Stem Cells.
Animal Study on Disc Degeneration, published in Tissue Eng Regen Med (2026) — summary generated from the PubMed abstract.
- 2026
Tissue Eng Regen Med - Level DAnimal StudyEurope PMC
Heme oxygenase 1‑overexpressing bone marrow mesenchymal stem cell‑derived exosomes suppress interleukin‑1 beta‑induced apoptosis and aging of nucleus pulposus cells
Animal Study on Disc Degeneration, published in Mol Med Rep (2025) — summary generated from the PubMed abstract.
- 2025
Mol Med Rep1 citations - Level DLaboratory StudyPubMed
Viscoelastic hydrogels regulate adipose-derived mesenchymal stem cells for nucleus pulposus regeneration.
Laboratory Study on Back Pain, Disc Degeneration, published in Acta Biomater (2024) — summary generated from the PubMed abstract.
- 2024
Acta Biomater19 citations - Level DLaboratory StudyPubMed
Mesenchymal stem cell-derived secretome enhances nucleus pulposus cell metabolism and modulates extracellular matrix gene expression in vitro .
Laboratory Study on Back Pain, Disc Degeneration, published in Front Bioeng Biotechnol (2023) — summary generated from the PubMed abstract.
- 2023
Front Bioeng Biotechnol22 citations - Level DAnimal StudyPubMed
Hypoxia regulates adipose mesenchymal stem cells proliferation, migration, and nucleus pulposus-like differentiation by regulating endoplasmic reticulum stress via the HIF-1α pathway.
Animal Study on Disc Degeneration, published in J Orthop Surg Res (2023) — summary generated from the PubMed abstract.
- 2023
J Orthop Surg Res - Level CProspective StudyEurope PMC
Sa12b Improves Biological Activity of Human Degenerative Nucleus Pulposus Mesenchymal Stem Cells in a Severe Acid Environment by Inhibiting Acid-Sensitive Ion Channels
Prospective Study on Back Pain, Disc Degeneration, published in Front Bioeng Biotechnol (2022) — summary generated from the PubMed abstract.
- 2022
Front Bioeng Biotechnol8 citations - Level DLaboratory StudyEurope PMC
Sa12b-Modified Functional Self-Assembling Peptide Hydrogel Enhances the Biological Activity of Nucleus Pulposus Mesenchymal Stem Cells by Inhibiting Acid-Sensing Ion Channels
Laboratory Study on Disc Degeneration, published in Front Cell Dev Biol (2022) — summary generated from the PubMed abstract.
- 2022
Front Cell Dev Biol19 citations - Level DLaboratory StudyPubMed
Enhancement of nucleus pulposus repair by glycoengineered adipose-derived mesenchymal cells.
Laboratory Study on Disc Degeneration, published in Biomaterials (2022) — summary generated from the PubMed abstract.
- 2022
Biomaterials16 citations - Level DAnimal StudyEurope PMC
Induction of notochordal differentiation of bone marrow mesenchymal‑derived stem cells via the stimulation of notochordal cell‑rich nucleus pulposus tissue
Animal Study on Disc Degeneration, published in Mol Med Rep (2021) — summary generated from the PubMed abstract.
- 2021
Mol Med Rep8 citations - Level DLaboratory StudyPubMed
Comprehensive RNA expression profile of therapeutic adipose‑derived mesenchymal stem cells co‑cultured with degenerative nucleus pulposus cells.
Laboratory Study on Disc Degeneration, published in Mol Med Rep (2021) — summary generated from the PubMed abstract.
- 2021
Mol Med Rep3 citations - Level DLaboratory StudyPubMed
Site-Directed Differentiation of Human Adipose-Derived Mesenchymal Stem Cells to Nucleus Pulposus Cells Using an Injectable Hydroxyl-Functional Diblock Copolymer Worm Gel.
Laboratory Study on Back Pain, Disc Degeneration, published in Biomacromolecules (2021) — summary generated from the PubMed abstract.
- 2021
Biomacromolecules12 citations - Level DLaboratory StudyPubMed
Comparison of the differentiation abilities of bone marrow-derived mesenchymal stem cells and adipose-derived mesenchymal stem cells toward nucleus pulposus-like cells in three-dimensional culture.
Laboratory Study on Disc Degeneration, published in Exp Ther Med (2021) — summary generated from the PubMed abstract.
- 2021
Exp Ther Med15 citations - Level DAnimal StudyEurope PMC
Exosomes Derived from Bone Mesenchymal Stem Cells Alleviate Compression-Induced Nucleus Pulposus Cell Apoptosis by Inhibiting Oxidative Stress
Animal Study on Disc Degeneration, published in Oxid Med Cell Longev (2021) — summary generated from the PubMed abstract.
- 2021
Oxid Med Cell Longev38 citations - Level DLaboratory StudyEurope PMC
Effect of Conditioned Medium from Human Umbilical Cord-Derived Mesenchymal Stromal Cells on Rejuvenation of Nucleus Pulposus Derived Stem/Progenitor Cells from Degenerated Intervertebral Disc
Laboratory Study on Disc Degeneration, published in Int J Stem Cells (2020) — summary generated from the PubMed abstract.
- 2020
Int J Stem Cells15 citations - Level DLaboratory StudyEurope PMC
Mesenchymal stem cells regulate inflammatory milieu within degenerative nucleus pulposus cells via p38 MAPK pathway
Laboratory Study on Disc Degeneration, Chronic Inflammation, published in Exp Ther Med (2020) — summary generated from the PubMed abstract.
- 2020
Exp Ther Med11 citations - Level DAnimal StudyPubMed
Small Molecule-Based Strategy Promotes Nucleus Pulposus Specific Differentiation of Adipose-Derived Mesenchymal Stem Cells.
Animal Study on Disc Degeneration, published in Mol Cells (2019) — summary generated from the PubMed abstract.
- 2019
Mol Cells13 citations - Level DLaboratory StudyPubMed
Aberrantly expressed messenger RNAs and long noncoding RNAs in degenerative nucleus pulposus cells co-cultured with adipose-derived mesenchymal stem cells.
Laboratory Study on Disc Degeneration, published in Arthritis Res Ther (2018) — summary generated from the PubMed abstract.
- 2018
Arthritis Res Ther14 citations - Level DLaboratory StudyPubMed
Proportion of collagen type II in the extracellular matrix promotes the differentiation of human adipose-derived mesenchymal stem cells into nucleus pulposus cells.
Laboratory Study, published in Biofactors (2016) — summary generated from the PubMed abstract.
- 2016
Biofactors31 citations - Level DAnimal StudyPubMed
The potential of chondrogenic pre-differentiation of adipose-derived mesenchymal stem cells for regeneration in harsh nucleus pulposus microenvironment.
Animal Study on Disc Degeneration, published in Exp Biol Med (Maywood) (2016) — summary generated from the PubMed abstract.
- 2016
Exp Biol Med (Maywood)20 citations - Level DAnimal StudyPubMed
Dynamic compression and co-culture with nucleus pulposus cells promotes proliferation and differentiation of adipose-derived mesenchymal stem cells.
Animal Study on Disc Degeneration, published in J Biomech (2014) — summary generated from the PubMed abstract.
- 2014
J Biomech25 citations - Level DLaboratory StudyPubMed
Growth differentiation factor 6 and transforming growth factor-beta differentially mediate mesenchymal stem cell differentiation, composition, and micromechanical properties of nucleus pulposus constructs.
Laboratory Study on Back Pain, Disc Degeneration, published in Arthritis Res Ther (2014) — summary generated from the PubMed abstract.
- 2014
Arthritis Res Ther - Level DAnimal StudyPubMed
Nucleus pulposus mesenchymal stem cells in acidic conditions mimicking degenerative intervertebral discs give better performance than adipose tissue-derived mesenchymal stem cells.
Animal Study on Disc Degeneration, published in Cells Tissues Organs (2014) — summary generated from the PubMed abstract.
- 2014
Cells Tissues Organs - Level DAnimal StudyPubMed
Influence of hypoxia in the intervertebral disc on the biological behaviors of rat adipose- and nucleus pulposus-derived mesenchymal stem cells.
Animal Study on Disc Degeneration, published in Cells Tissues Organs (2013) — summary generated from the PubMed abstract.
- 2013
Cells Tissues Organs55 citations
In-depth reviewed studies (full Thai translation)
Evidence system- Level ARandomized Controlled Trial
Cell-based versus corticosteroid injections for knee pain in osteoarthritis: a randomized phase 3 trial
A multicentre randomized trial in 480 knee osteoarthritis patients comparing SVF, BMAC and umbilical cord MSCs against corticosteroid injection. At 12 months no cell product outperformed the steroid control.
- 2023
- United States
- n = 480
- Level AMeta-analysis
Intra-articular Injection of Autologous Adipose-Derived Stem Cells or Stromal Vascular Fractions: Are They Effective for Patients With Knee Osteoarthritis? A Systematic Review With Meta-analysis of Randomized Controlled Trials
Pooled five RCTs comparing ADSC/SVF injection with placebo or hyaluronic acid, finding significant pain and function improvement at 6 and 12 months.
- 2023
- South Korea
- Level AMeta-analysis
Rapid-acting pain relief in knee osteoarthritis: autologous-cultured adipose-derived mesenchymal stem cells outperform stromal vascular fraction: a systematic review and meta-analysis
Analysed 31 studies with 1,406 patients: cultured ADMSCs reduced pain from month 3, whereas SVF reached significance only at 12 months.
- 2024
- South Korea
- n = 1406