Research database
SVF Research Library
Search 52,792 real PubMed studies on SVF and adipose-derived stem cells — 19 matching records.
19 results — page 1 of 1
- Level DLaboratory StudyPubMed
Exosomes from APCs ameliorate human skin fibroblast senescence via p53/p21 signaling pathway.
Laboratory Study on Skin Aging, published in Tissue Cell (2026) — summary generated from the PubMed abstract.
- 2026
Tissue Cell - Level DAnimal StudyPubMed
Mossy-textured hydroxyapatite-modified poly (lactic-co-glycolic acid) microspheres promote collagen regeneration via calcium/TGF-β and chemokine signaling pathways in soft tissue augmentation.
Animal Study on Skin Aging, Chronic Inflammation, published in Bioact Mater (2025) — summary generated from the PubMed abstract.
- 2025
Bioact Mater - Level DNarrative ReviewEurope PMC
Targeting Crosstalk of Signaling Pathways among Muscles-Bone-Adipose Tissue: A Promising Therapeutic Approach for Sarcopenia
Narrative Review on Hip, published in Aging Dis (2024) — summary generated from the PubMed abstract.
- 2024
Aging Dis13 citations - Level DLaboratory StudyEurope PMC
MiR-4298 and lncKRTAP5-6-3 regulated Cathepsin D expression through ERK-MAPK signaling pathway in chronic UVB-damaged HaCaT cells
Laboratory Study on Skin Aging, published in Front Med (Lausanne) (2024) — summary generated from the PubMed abstract.
- 2024
Front Med (Lausanne) - Level CProspective StudyEurope PMC
Mechanisms of human umbilical cord mesenchymal stem cells-derived exosomal lncRNA GAS5 in alleviating EMT of HPMCs via Wnt/β-catenin signaling pathway
Prospective Study, published in Aging (Albany NY) (2023) — summary generated from the PubMed abstract.
- 2023
Aging (Albany NY)13 citations - Level DAnimal StudyEurope PMC
Downregulating miR-184 relieves calcium oxalate crystal-mediated renal cell damage via activating the Rap1 signaling pathway
Animal Study on Hip, Systemic / IV, published in Aging (Albany NY) (2023) — summary generated from the PubMed abstract.
- 2023
Aging (Albany NY)4 citations - Level DLaboratory StudyEurope PMC
lncRNA HHIP-AS1/HHIP modulates osteogenic differentiation of BM-MSCs by regulating Hedgehog signaling pathway
Laboratory Study on Hip, published in Aging (Albany NY) (2022) — summary generated from the PubMed abstract.
- 2022
Aging (Albany NY)4 citations - Level DLaboratory StudyEurope PMC
Exosomes derived from human umbilical cord mesenchymal stem cells promote osteogenesis through the AKT signaling pathway in postmenopausal osteoporosis
Laboratory Study, published in Aging (Albany NY) (2022) — summary generated from the PubMed abstract.
- 2022
Aging (Albany NY)6 citations - Level DAnimal StudyEurope PMC
Human umbilical cord mesenchymal stem cell-derived exosomal miR-146a-5p reduces microglial-mediated neuroinflammation via suppression of the IRAK1/TRAF6 signaling pathway after ischemic stroke
Animal Study on Stroke Research, Neuroinflammation, Chronic Inflammation, published in Aging (Albany NY) (2021) — summary generated from the PubMed abstract.
- 2021
Aging (Albany NY)155 citations - Level DAnimal StudyEurope PMC
Adipogenic differentiation was inhibited by downregulation of PPARγ signaling pathway in aging tendon stem/progenitor cells
Animal Study on Tendon Injury, published in J Orthop Surg Res (2021) — summary generated from the PubMed abstract.
- 2021
J Orthop Surg Res13 citations - Level DLaboratory StudyPubMed
Chondroprotective Effects of Combination Therapy of Acupotomy and Human Adipose Mesenchymal Stem Cells in Knee Osteoarthritis Rabbits via the GSK3β-Cyclin D1-CDK4/CDK6 Signaling Pathway.
Laboratory Study on Knee Osteoarthritis, Osteoarthritis, Cartilage Damage, published in Aging Dis (2020) — summary generated from the PubMed abstract.
- 2020
Aging Dis20 citations - Level DLaboratory StudyPubMed
miR-100-3p inhibits the adipogenic differentiation of hMSCs by targeting PIK3R1 via the PI3K/AKT signaling pathway.
Laboratory Study, published in Aging (Albany NY) (2020) — summary generated from the PubMed abstract.
- 2020
Aging (Albany NY) - Level DAnimal StudyPubMed
HGF and BFGF Secretion by Human Adipose-Derived Stem Cells Improves Ovarian Function During Natural Aging via Activation of the SIRT1/FOXO1 Signaling Pathway.
Animal Study on Hair & Scalp, published in Cell Physiol Biochem (2018) — summary generated from the PubMed abstract.
- 2018
Cell Physiol Biochem38 citations - Level DAnimal StudyPubMed
MiRNA-10b Reciprocally Stimulates Osteogenesis and Inhibits Adipogenesis Partly through the TGF-β/SMAD2 Signaling Pathway.
Animal Study, published in Aging Dis (2018) — summary generated from the PubMed abstract.
- 2018
Aging Dis76 citations - Level DAnimal StudyEurope PMC
Protective Effect of Ginsenoside Rg1 on Hematopoietic Stem/Progenitor Cells through Attenuating Oxidative Stress and the Wnt/β-Catenin Signaling Pathway in a Mouse Model of d-Galactose-induced Aging
Animal Study, published in Int J Mol Sci (2016) — summary generated from the PubMed abstract.
- 2016
Int J Mol Sci63 citations - Level DNarrative ReviewEurope PMC
Regulation and Role of TGFβ Signaling Pathway in Aging and Osteoarthritis Joints
Narrative Review on Osteoarthritis, Cartilage Damage, published in Aging Dis (2014) — summary generated from the PubMed abstract.
- 2014
Aging Dis52 citations - Level DAnimal StudyPubMed
Adipose stromal cells amplify angiogenic signaling via the VEGF/mTOR/Akt pathway in a murine hindlimb ischemia model: a 3D multimodality imaging study.
Animal Study on Peripheral Artery Disease, published in PLoS One (2012) — summary generated from the PubMed abstract.
- 2012
PLoS One38 citations - Level DNarrative ReviewEurope PMC
The Wnt signaling pathway: aging gracefully as a protectionist?
Narrative Review on Neuroinflammation, published in Pharmacol Ther (2008) — summary generated from the PubMed abstract.
- 2008
Pharmacol Ther140 citations - Level DAnimal StudyPubMed
Aging activates adipogenic and suppresses osteogenic programs in mesenchymal marrow stroma/stem cells: the role of PPAR-gamma2 transcription factor and TGF-beta/BMP signaling pathways.
Animal Study, published in Aging Cell (2004) — summary generated from the PubMed abstract.
- 2004
Aging Cell
In-depth reviewed studies (full Thai translation)
Evidence system- Level ARandomized Controlled Trial
Cell-based versus corticosteroid injections for knee pain in osteoarthritis: a randomized phase 3 trial
A multicentre randomized trial in 480 knee osteoarthritis patients comparing SVF, BMAC and umbilical cord MSCs against corticosteroid injection. At 12 months no cell product outperformed the steroid control.
- 2023
- United States
- n = 480
- Level AMeta-analysis
Intra-articular Injection of Autologous Adipose-Derived Stem Cells or Stromal Vascular Fractions: Are They Effective for Patients With Knee Osteoarthritis? A Systematic Review With Meta-analysis of Randomized Controlled Trials
Pooled five RCTs comparing ADSC/SVF injection with placebo or hyaluronic acid, finding significant pain and function improvement at 6 and 12 months.
- 2023
- South Korea
- Level AMeta-analysis
Rapid-acting pain relief in knee osteoarthritis: autologous-cultured adipose-derived mesenchymal stem cells outperform stromal vascular fraction: a systematic review and meta-analysis
Analysed 31 studies with 1,406 patients: cultured ADMSCs reduced pain from month 3, whereas SVF reached significance only at 12 months.
- 2024
- South Korea
- n = 1406