Research database
SVF Research Library
Search 52,792 real PubMed studies on SVF and adipose-derived stem cells — 25 matching records.
25 results — page 1 of 2
- Level BRandomized Controlled TrialPubMed
Combination ex vivo regional gene therapy with sonic hedgehog and bone morphogenetic protein-2 does not enhance bone healing in critical size defects.
Randomized Controlled Trial, published in Connect Tissue Res (2026) — summary generated from the PubMed abstract.
- 2026
Connect Tissue Res - Level DAnimal StudyEurope PMC
Ex Vivo Regional Gene Therapy Compared to Recombinant BMP-2 for the Treatment of Critical-Size Bone Defects: An In Vivo Single-Cell RNA-Sequencing Study
Animal Study on Cartilage Damage, Chronic Inflammation, published in Bioengineering (Basel) (2025) — summary generated from the PubMed abstract.
- 2025
Bioengineering (Basel)2 citations - Level CProspective StudyEurope PMC
In vivo generation of CAR macrophages via the enucleated mesenchymal stem cell delivery system for glioblastoma therapy
Prospective Study, published in Proc Natl Acad Sci U S A (2025) — summary generated from the PubMed abstract.
- 2025
Proc Natl Acad Sci U S A7 citations - Level CCohort StudyPubMed
In vivo effects of cell seeding technique in an ex vivo regional gene therapy model for bone regeneration.
Cohort Study, published in J Biomed Mater Res A (2024) — summary generated from the PubMed abstract.
- 2024
J Biomed Mater Res A1 citations - Level CProspective StudyPubMed
Biodistribution of lentiviral transduced adipose-derived stem cells for "ex-vivo" regional gene therapy for bone repair.
Prospective Study, published in Gene Ther (2023) — summary generated from the PubMed abstract.
- 2023
Gene Ther5 citations - Level CCohort StudyPubMed
Human Bone Marrow versus Adipose-Derived Stem Cells: Influence of Donor Characteristics on Expandability and Implications for Osteogenic Ex Vivo BMP-2 Regional Gene Therapy.
Cohort Study on Knee, published in J Tissue Eng Regen Med (2023) — summary generated from the PubMed abstract.
- 2023
J Tissue Eng Regen Med - Level DAnimal StudyPubMed
Gene-Directed Enzyme/Prodrug Therapy of Rat Brain Tumor Mediated by Human Mesenchymal Stem Cell Suicide Gene Extracellular Vesicles In Vitro and In Vivo.
Animal Study, published in Cancers (Basel) (2022) — summary generated from the PubMed abstract.
- 2022
Cancers (Basel) - Level DAnimal StudyEurope PMC
In Vitro and Ectopic In Vivo Studies toward the Utilization of Rapidly Isolated Human Nasal Chondrocytes for Single-Stage Arthroscopic Cartilage Regeneration Therapy
Animal Study on Cartilage Damage, published in Int J Mol Sci (2022) — summary generated from the PubMed abstract.
- 2022
Int J Mol Sci4 citations - Level DAnimal StudyEurope PMC
Temporomandibular Joint Osteoarthritis: Regenerative Treatment by a Stem Cell Containing Advanced Therapy Medicinal Product (ATMP)-An In Vivo Animal Trial
Animal Study on Osteoarthritis, Cartilage Damage, published in Int J Mol Sci (2021) — summary generated from the PubMed abstract.
- 2021
Int J Mol Sci28 citations - Level ASystematic ReviewEurope PMC
In Vitro and In Vivo Effects of Light Therapy on Cartilage Regeneration for Knee Osteoarthritis: A Systematic Review
Systematic Review on Knee Osteoarthritis, Osteoarthritis, Cartilage Damage, published in Cartilage (2021) — summary generated from the PubMed abstract.
- 2021
Cartilage15 citations - Level DAnimal StudyEurope PMC
Comparison of experimental peri-implantitis models after application of ex vivo BMP2 gene therapy using periodontal ligament stem cells
Animal Study on Ligament Injury, published in Sci Rep (2020) — summary generated from the PubMed abstract.
- 2020
Sci Rep5 citations - Level CProspective StudyPubMed
Ex vivo regional gene therapy with human adipose-derived stem cells for bone repair.
Prospective Study with a reported sample of 14, published in Bone (2020) — summary generated from the PubMed abstract.
- 2020
- n = 14
Bone20 citations - Level BRandomized Controlled TrialPubMed
Regenerative Therapy by Suprachoroidal Cell Autograft in Dry Age-related Macular Degeneration: Preliminary In Vivo Report.
Randomized Controlled Trial with a reported sample of 11, published in J Vis Exp (2018) — summary generated from the PubMed abstract.
- 2018
- n = 11
J Vis Exp28 citations - Level DLaboratory StudyPubMed
Cryopreservation of Human Adipose-Derived Stem Cells for Use in Ex Vivo Regional Gene Therapy for Bone Repair.
Laboratory Study, published in Hum Gene Ther Methods (2018) — summary generated from the PubMed abstract.
- 2018
Hum Gene Ther Methods11 citations - Level DAnimal StudyPubMed
An ex vivo gene therapy approach in X-linked retinoschisis.
Animal Study, published in Mol Vis (2016) — summary generated from the PubMed abstract.
- 2016
Mol Vis - Level DLaboratory StudyPubMed
Autologous cell sources in therapeutic vasculogenesis: In vitro and in vivo comparison of endothelial colony-forming cells from peripheral blood and endothelial cells isolated from adipose tissue.
Laboratory Study on Face & Skin, published in Cytotherapy (2015) — summary generated from the PubMed abstract.
- 2015
Cytotherapy - Level CProspective StudyPubMed
Synergistic effect of bone morphogenetic proteins 2 and 7 by ex vivo gene therapy in a rat spinal fusion model.
Prospective Study on Back & Spine, published in J Bone Joint Surg Am (2013) — summary generated from the PubMed abstract.
- 2013
J Bone Joint Surg Am21 citations - Level DAnimal StudyPubMed
PAMAM dendrimer-baculovirus nanocomplex for microencapsulated adipose stem cell-gene therapy: in vitro and in vivo functional assessment.
Animal Study on Cardiovascular Disease, Chronic Wound, published in Mol Pharm (2012) — summary generated from the PubMed abstract.
- 2012
Mol Pharm21 citations - Level DNarrative ReviewEurope PMC
Adipocytes as a vehicle for ex vivo gene therapy: Novel replacement therapy for diabetes and other metabolic diseases
Narrative Review on Systemic / IV, published in J Diabetes Investig (2011) — summary generated from the PubMed abstract.
- 2011
J Diabetes Investig10 citations - Level DAnimal StudyPubMed
Regenerative therapy and cancer: in vitro and in vivo studies of the interaction between adipose-derived stem cells and breast cancer cells from clinical isolates.
Animal Study, published in Tissue Eng Part A (2010) — summary generated from the PubMed abstract.
- 2010
Tissue Eng Part A151 citations - Level DAnimal StudyPubMed
Adipose-derived stem cells modified genetically in vivo promote reconstruction of bone defects.
Animal Study, published in Cytotherapy (2010) — summary generated from the PubMed abstract.
- 2010
Cytotherapy31 citations - Level BClinical TrialPubMed
Comparison of human mesenchymal stem cells derived from adipose tissue and bone marrow for ex vivo gene therapy in rat spinal fusion model.
Clinical Trial with a reported sample of 10 on Back & Spine, published in Spine (Phila Pa 1976) (2008) — summary generated from the PubMed abstract.
- 2008
- n = 10
Spine (Phila Pa 1976) - Level DAnimal StudyPubMed
Comparison of mesenchymal tissues-derived stem cells for in vivo chondrogenesis: suitable conditions for cell therapy of cartilage defects in rabbit.
Animal Study on Cartilage Damage, published in Cell Tissue Res (2008) — summary generated from the PubMed abstract.
- 2008
Cell Tissue Res - Level CProspective StudyPubMed
In vitro and in vivo induction of bone formation based on adeno-associated virus-mediated BMP-7 gene therapy using human adipose-derived mesenchymal stem cells.
Prospective Study, published in Acta Pharmacol Sin (2007) — summary generated from the PubMed abstract.
- 2007
Acta Pharmacol Sin28 citations
In-depth reviewed studies (full Thai translation)
Evidence system- Level ARandomized Controlled Trial
Cell-based versus corticosteroid injections for knee pain in osteoarthritis: a randomized phase 3 trial
A multicentre randomized trial in 480 knee osteoarthritis patients comparing SVF, BMAC and umbilical cord MSCs against corticosteroid injection. At 12 months no cell product outperformed the steroid control.
- 2023
- United States
- n = 480
- Level AMeta-analysis
Intra-articular Injection of Autologous Adipose-Derived Stem Cells or Stromal Vascular Fractions: Are They Effective for Patients With Knee Osteoarthritis? A Systematic Review With Meta-analysis of Randomized Controlled Trials
Pooled five RCTs comparing ADSC/SVF injection with placebo or hyaluronic acid, finding significant pain and function improvement at 6 and 12 months.
- 2023
- South Korea
- Level AMeta-analysis
Rapid-acting pain relief in knee osteoarthritis: autologous-cultured adipose-derived mesenchymal stem cells outperform stromal vascular fraction: a systematic review and meta-analysis
Analysed 31 studies with 1,406 patients: cultured ADMSCs reduced pain from month 3, whereas SVF reached significance only at 12 months.
- 2024
- South Korea
- n = 1406