Research database
SVF Research Library
Search 52,792 real PubMed studies on SVF and adipose-derived stem cells — 335 matching records.
335 results — page 1 of 14
- Level CProspective StudyEurope PMC
GDF3 promotes adipose tissue macrophage-mediated inflammation via altered chromatin accessibility during aging
Prospective Study with a reported sample of 84 on Systemic / IV, published in Nat Aging (2026) — summary generated from the PubMed abstract.
- 2026
- n = 84
Nat Aging5 citations - Level DAnimal StudyEurope PMC
Anti-Diabetic Effects of Ayanin, a Flavonoid Compound, in STZ/HFD-Induced Diabetic Mice by Upregulating GLUT4 and Suppressing Macrophage-Driven Inflammation in Adipose Tissues
Animal Study on Type 2 Diabetes, published in Food Sci Nutr (2026) — summary generated from the PubMed abstract.
- 2026
Food Sci Nutr - Level DAnimal StudyEurope PMC
Obesity-induced pyroptotic adipocyte death leads to TREM2-dependent macrophage dysfunction and adipose tissue inflammation
Animal Study on Chronic Inflammation, published in iScience (2026) — summary generated from the PubMed abstract.
- 2026
iScience2 citations - Level DAnimal StudyEurope PMC
CD9 regulates macrophage-mediated remodeling of adipose tissue in obesity
Animal Study on Type 2 Diabetes, published in JCI Insight (2026) — summary generated from the PubMed abstract.
- 2026
JCI Insight - Level DLaboratory StudyEurope PMC
Adipose tissue-derived MFG-E8 promotes hepatic inflammation and fibrosis through macrophage activation in a mouse MASH model
Laboratory Study, published in NPJ Metab Health Dis (2026) — summary generated from the PubMed abstract.
- 2026
NPJ Metab Health Dis - Level DNarrative ReviewPubMed
Adipose-Tissue Macrophage Diversity and Functions.
Narrative Review, published in Int J Mol Sci (2026) — summary generated from the PubMed abstract.
- 2026
Int J Mol Sci - Level CProspective StudyEurope PMC
The exosomal miR-26b-3p derived from Crohn's disease-associated mesenteric adipose tissue induces M1 macrophage polarization and exacerbates ileocolonic anastomosis inflammation via the p38-MAPK signaling pathway
Prospective Study on Chronic Inflammation, Autoimmune Research, published in Front Immunol (2026) — summary generated from the PubMed abstract.
- 2026
Front Immunol1 citations - Level DLaboratory StudyPubMed
Secretome From Human Micro-Fragmented Adipose Tissue Affects In Vitro Monocytes/Macrophages Inflammatory Activity by ICAM-1 Expression.
Laboratory Study on Chronic Inflammation, published in Mediators Inflamm (2026) — summary generated from the PubMed abstract.
- 2026
Mediators Inflamm - Level DNarrative ReviewEurope PMC
Targeted regulation of adipose tissue macrophages from an immunometabolic perspective: a novel therapeutic approach for obesity-related metabolic disorders
Narrative Review on Type 2 Diabetes, Chronic Inflammation, published in Front Immunol (2026) — summary generated from the PubMed abstract.
- 2026
Front Immunol1 citations - Level DAnimal StudyEurope PMC
CD14<sup>lo</sup>CD301b<sup>+</sup> macrophages gathering as a proangiogenic marker in adipose tissues
Animal Study on Hip, published in J Lipid Res (2025) — summary generated from the PubMed abstract.
- 2025
J Lipid Res2 citations - Level DAnimal StudyPubMed
Blocking the SIRPα-CD47 axis promotes macrophage phagocytosis of exosomes derived from visceral adipose tissue and improves inflammation and metabolism in mice.
Animal Study on Systemic / IV, published in J Biomed Sci (2025) — summary generated from the PubMed abstract.
- 2025
J Biomed Sci8 citations - Level DAnimal StudyPubMed
Effects of macrophages on the osteogenic differentiation of adipose tissue-derived stem cells in two-dimensional and three-dimensional cocultures.
Animal Study, published in World J Stem Cells (2025) — summary generated from the PubMed abstract.
- 2025
World J Stem Cells - Level DAnimal StudyEurope PMC
Novel Cell-to-Cell Communications Between Macrophages and Fibroblasts Regulate Obesity-Induced Adipose Tissue Fibrosis
Animal Study, published in Diabetes (2025) — summary generated from the PubMed abstract.
- 2025
Diabetes13 citations - Level DAnimal StudyEurope PMC
BNIP3-mediated mitophagy in macrophages regulates obesity-induced adipose tissue metaflammation
Animal Study on Type 2 Diabetes, published in Autophagy (2025) — summary generated from the PubMed abstract.
- 2025
Autophagy5 citations - Level DAnimal StudyEurope PMC
Targeting IRE1α improves insulin sensitivity and thermogenesis and suppresses metabolically active adipose tissue macrophages in male obese mice
Animal Study on Type 2 Diabetes, published in Elife (2025) — summary generated from the PubMed abstract.
- 2025
Elife5 citations - Level DAnimal StudyPubMed
Exosomal miR-1246 of adipose stem cells attenuates obesity by polarizing M2 macrophages, reducing fat mass, and beiging of white adipose tissue.
Animal Study on Hip, published in J Adv Res (2025) — summary generated from the PubMed abstract.
- 2025
J Adv Res5 citations - Level DAnimal StudyPubMed
Transglutaminase 2-expressing macrophages modulate adipose tissue inflammation.
Animal Study on Type 2 Diabetes, Chronic Inflammation, published in Commun Biol (2025) — summary generated from the PubMed abstract.
- 2025
Commun Biol - Level DAnimal StudyPubMed
High-fat diet-induced adipose tissue-resident macrophages, T cells, and dendritic cells modulate chronic inflammation and adipogenesis during obesity.
Animal Study on Chronic Inflammation, published in Front Immunol (2025) — summary generated from the PubMed abstract.
- 2025
Front Immunol11 citations - Level CProspective StudyEurope PMC
Lipid-associated macrophages are more abundant in subcutaneous than visceral adipose tissue in patients with obesity
Prospective Study on Type 2 Diabetes, published in Obesity (Silver Spring) (2025) — summary generated from the PubMed abstract.
- 2025
Obesity (Silver Spring)6 citations - Level DAnimal StudyEurope PMC
Thyroid Stimulating Hormone May Facilitates Adipose Tissue Insulin Resistance by Inducing M1 Macrophage Polarization
Animal Study on Type 2 Diabetes, published in J Inflamm Res (2025) — summary generated from the PubMed abstract.
- 2025
J Inflamm Res2 citations - Level BClinical TrialEurope PMC
Adipose Tissue Macrophages as Initiators of Exacerbated Periodontitis in Estrogen-Deficient Environments via the Amplifier Extracellular Vesicles
Clinical Trial on Systemic / IV, published in Adv Sci (Weinh) (2025) — summary generated from the PubMed abstract.
- 2025
Adv Sci (Weinh)6 citations - Level DAnimal StudyPubMed
Ox-LDL-stimulated macrophage-derived exosomes regulate adipose tissue remodeling and promote the progression of atherosclerosis.
Animal Study, published in Mol Cell Endocrinol (2025) — summary generated from the PubMed abstract.
- 2025
Mol Cell Endocrinol - Level DAnimal StudyEurope PMC
Nanomedicine targeting PPAR in adipose tissue macrophages improves lipid metabolism and obesity-induced metabolic dysfunction
Animal Study on Systemic / IV, published in Sci Adv (2025) — summary generated from the PubMed abstract.
- 2025
Sci Adv3 citations - Level CProspective StudyPubMed
[Metabolic dysregulation in adipose tissue macrophages and its link to obesity and obesity with type 2 diabetes based on single-cell transcriptome sequencing].
Prospective Study on Type 2 Diabetes, published in Zhonghua Yi Xue Za Zhi (2025) — summary generated from the PubMed abstract.
- 2025
Zhonghua Yi Xue Za Zhi
In-depth reviewed studies (full Thai translation)
Evidence system- Level ARandomized Controlled Trial
Cell-based versus corticosteroid injections for knee pain in osteoarthritis: a randomized phase 3 trial
A multicentre randomized trial in 480 knee osteoarthritis patients comparing SVF, BMAC and umbilical cord MSCs against corticosteroid injection. At 12 months no cell product outperformed the steroid control.
- 2023
- United States
- n = 480
- Level AMeta-analysis
Intra-articular Injection of Autologous Adipose-Derived Stem Cells or Stromal Vascular Fractions: Are They Effective for Patients With Knee Osteoarthritis? A Systematic Review With Meta-analysis of Randomized Controlled Trials
Pooled five RCTs comparing ADSC/SVF injection with placebo or hyaluronic acid, finding significant pain and function improvement at 6 and 12 months.
- 2023
- South Korea
- Level AMeta-analysis
Rapid-acting pain relief in knee osteoarthritis: autologous-cultured adipose-derived mesenchymal stem cells outperform stromal vascular fraction: a systematic review and meta-analysis
Analysed 31 studies with 1,406 patients: cultured ADMSCs reduced pain from month 3, whereas SVF reached significance only at 12 months.
- 2024
- South Korea
- n = 1406