Research database
SVF Research Library
Search 52,792 real PubMed studies on SVF and adipose-derived stem cells — 30 matching records.
30 results — page 1 of 2
- Level ASystematic ReviewEurope PMC
Intraoperative Autologous Adipose-Derived Therapies and PRP as Add-On in the Surgical Treatment of Cryptoglandular and Crohn's Disease-Related Perianal Fistula-A Systematic Review
Systematic Review with a reported sample of 1017 on Autoimmune Research, published in Bioengineering (Basel) (2026) — summary generated from the PubMed abstract.
- 2026
- n = 1017
Bioengineering (Basel) - Level CProspective StudyEurope PMC
Mesenteric adipose-derived exosomal TINAGL1 enhances intestinal fibrosis in Crohn's Disease via SMAD4
Prospective Study on Autoimmune Research, published in J Adv Res (2025) — summary generated from the PubMed abstract.
- 2025
J Adv Res10 citations - Level ASystematic ReviewPubMed
Therapeutic potential and mechanistic insights into adipose-derived stem cells and mesenchymal stem cell-derived exosomes in patients with Crohn's disease-associated fistulas: challenges and future perspectives.
Systematic Review on Autoimmune Research, published in Stem Cell Res Ther (2025) — summary generated from the PubMed abstract.
- 2025
Stem Cell Res Ther2 citations - Level BClinical TrialPubMed
Rationale and design of the AlloFIST trial: a phase I/IIa study to evaluate dose escalation of allogeneic adipose-derived stroma/stem cells for the treatment of Crohn's fistula.
Clinical Trial on Osteoarthritis, Chronic Wound, Chronic Inflammation, Autoimmune Research, published in BMJ Open (2025) — summary generated from the PubMed abstract.
- 2025
BMJ Open - Level ASystematic ReviewPubMed
The efficacy of adipose-derived stem cell therapy for complex perianal fistulas in Crohn's disease patients: A systematic review.
Systematic Review with a reported sample of 19 on Chronic Inflammation, Autoimmune Research, published in Surg Open Sci (2025) — summary generated from the PubMed abstract.
- 2025
- n = 19
Surg Open Sci - Level CProspective StudyPubMed
[A new treatment option for complex perianal fistulas in Crohn's disease patients; development of darvadstrocel (allogeneic expanded adipose-derived mesenchymal stem cells) in Japan].
Prospective Study on Chronic Inflammation, Immune Modulation, Autoimmune Research, published in Nihon Yakurigaku Zasshi (2024) — summary generated from the PubMed abstract.
- 2024
Nihon Yakurigaku Zasshi - Level CCohort StudyPubMed
Real-life effectiveness of allogeneic expanded adipose-derived mesenchymal stem cell therapy for perianal fistulizing refractory Crohn's disease.
Cohort Study with a reported sample of 36 on Scar, Autoimmune Research, published in Clin Res Hepatol Gastroenterol (2024) — summary generated from the PubMed abstract.
- 2024
- n = 36
Clin Res Hepatol Gastroenterol - Level DAnimal StudyPubMed
GAS6 From CD200+ Adipose-Derived Stem Cells Mitigates Colonic Inflammation in a Macrophage-Dependent Manner.
Animal Study on Immune Modulation, published in J Crohns Colitis (2023) — summary generated from the PubMed abstract.
- 2023
J Crohns Colitis11 citations - Level CProspective StudyPubMed
Exosomal miR-103a-3p from Crohn's Creeping Fat-Derived Adipose-Derived Stem Cells Contributes to Intestinal Fibrosis by Targeting TGFBR3 and Activating Fibroblasts.
Prospective Study on Autoimmune Research, published in J Crohns Colitis (2023) — summary generated from the PubMed abstract.
- 2023
J Crohns Colitis24 citations - Level BClinical TrialPubMed
Allogeneic expanded adipose-derived mesenchymal stem cell therapy for perianal fistulas in Crohn's disease: A case series.
Clinical Trial with a reported sample of 11 on Immune Modulation, Autoimmune Research, published in Colorectal Dis (2021) — summary generated from the PubMed abstract.
- 2021
- n = 11
Colorectal Dis23 citations - Level BClinical TrialPubMed
Adipose-Derived Stem Cells in the Treatment of Perianal Fistulas in Crohn's Disease: Rationale, Clinical Results and Perspectives.
Clinical Trial on Chronic Inflammation, Immune Modulation, Autoimmune Research, published in Int J Mol Sci (2021) — summary generated from the PubMed abstract.
- 2021
Int J Mol Sci26 citations - Level BClinical TrialPubMed
Autologous adipose-derived stem cells for the treatment of Crohn's fistula-in-ano: an open-label, controlled trial.
Clinical Trial with a reported sample of 22 on Autoimmune Research, published in Stem Cell Res Ther (2020) — summary generated from the PubMed abstract.
- 2020
- n = 22
Stem Cell Res Ther46 citations - Level CCase Report / SeriesPubMed
Allogeneic expanded adipose-derived stem cells in the treatment of rectovaginal fistulas in Crohn's disease.
Case Report / Series on Autoimmune Research, published in Colorectal Dis (2020) — summary generated from the PubMed abstract.
- 2020
Colorectal Dis18 citations - Level ASystematic ReviewPubMed
TRANSPLANTATION OF ADIPOSE-DERIVED MESENCHYMAL STEM CELLS IN REFRACTORY CROHN'S DISEASE: SYSTEMATIC REVIEW.
Systematic Review on Scar, Autoimmune Research, published in Arq Bras Cir Dig (2019) — summary generated from the PubMed abstract.
- 2019
Arq Bras Cir Dig10 citations - Level CProspective StudyPubMed
First clinical case report of local microinjection of autologous fat and adipose-derived stromal vascular fraction for perianal fistula in Crohn's disease.
Prospective Study on Chronic Inflammation, Immune Modulation, Autoimmune Research, published in Stem Cell Res Ther (2018) — summary generated from the PubMed abstract.
- 2018
Stem Cell Res Ther22 citations - Level DAnimal StudyPubMed
Mesenteric Adipose-derived Stromal Cells From Crohn's Disease Patients Induce Protective Effects in Colonic Epithelial Cells and Mice With Colitis.
Animal Study on Chronic Inflammation, Autoimmune Research, published in Cell Mol Gastroenterol Hepatol (2018) — summary generated from the PubMed abstract.
- 2018
Cell Mol Gastroenterol Hepatol11 citations - Level BRandomized Controlled TrialPubMed
Local application of adipose-derived mesenchymal stem cells supports the healing of fistula: prospective randomised study on rat model of fistulising Crohn's disease.
Randomized Controlled Trial with a reported sample of 16 on Chronic Wound, Autoimmune Research, published in Scand J Gastroenterol (2017) — summary generated from the PubMed abstract.
- 2017
- n = 16
Scand J Gastroenterol13 citations - Level CProspective StudyPubMed
Crohn's Disease Disturbs the Immune Properties of Human Adipose-Derived Stem Cells Related to Inflammasome Activation.
Prospective Study on Immune Modulation, Autoimmune Research, published in Stem Cell Reports (2017) — summary generated from the PubMed abstract.
- 2017
Stem Cell Reports44 citations - Level BClinical TrialPubMed
Allogeneic adipose-derived stem cells for the treatment of perianal fistula in Crohn's disease: a pilot clinical trial.
Clinical Trial on Autoimmune Research, published in Colorectal Dis (2016) — summary generated from the PubMed abstract.
- 2016
Colorectal Dis42 citations - Level DAnimal StudyPubMed
Comparison of Adipose-Derived and Bone Marrow Mesenchymal Stromal Cells in a Murine Model of Crohn's Disease.
Animal Study on Immune Modulation, Autoimmune Research, published in Dig Dis Sci (2016) — summary generated from the PubMed abstract.
- 2016
Dig Dis Sci - Level BClinical TrialPubMed
Treatment of Crohn's-Related Rectovaginal Fistula With Allogeneic Expanded-Adipose Derived Stem Cells: A Phase I-IIa Clinical Trial.
Clinical Trial with a reported sample of 10 on Autoimmune Research, published in Stem Cells Transl Med (2016) — summary generated from the PubMed abstract.
- 2016
- n = 10
Stem Cells Transl Med78 citations - Level ARandomized Controlled TrialPubMed
Expanded allogeneic adipose-derived mesenchymal stem cells (Cx601) for complex perianal fistulas in Crohn's disease: a phase 3 randomised, double-blind controlled trial.
Randomized Controlled Trial with a reported sample of 212 on Autoimmune Research, published in Lancet (2016) — summary generated from the PubMed abstract.
- 2016
- n = 212
Lancet774 citations - Level DAnimal StudyPubMed
[Experimental study of adipose-derived mesenchymal stem cells in the treatment of Crohn's disease].
Animal Study on Chronic Inflammation, Autoimmune Research, published in Zhonghua Wei Chang Wai Ke Za Zhi (2015) — summary generated from the PubMed abstract.
- 2015
Zhonghua Wei Chang Wai Ke Za Zhi2 citations - Level BClinical TrialPubMed
Long-term results of adipose-derived stem cell therapy for the treatment of Crohn's fistula.
Clinical Trial with a reported sample of 26 on Chronic Wound, Autoimmune Research, published in Stem Cells Transl Med (2015) — summary generated from the PubMed abstract.
- 2015
- n = 26
Stem Cells Transl Med122 citations
In-depth reviewed studies (full Thai translation)
Evidence system- Level ARandomized Controlled Trial
Cell-based versus corticosteroid injections for knee pain in osteoarthritis: a randomized phase 3 trial
A multicentre randomized trial in 480 knee osteoarthritis patients comparing SVF, BMAC and umbilical cord MSCs against corticosteroid injection. At 12 months no cell product outperformed the steroid control.
- 2023
- United States
- n = 480
- Level AMeta-analysis
Intra-articular Injection of Autologous Adipose-Derived Stem Cells or Stromal Vascular Fractions: Are They Effective for Patients With Knee Osteoarthritis? A Systematic Review With Meta-analysis of Randomized Controlled Trials
Pooled five RCTs comparing ADSC/SVF injection with placebo or hyaluronic acid, finding significant pain and function improvement at 6 and 12 months.
- 2023
- South Korea
- Level AMeta-analysis
Rapid-acting pain relief in knee osteoarthritis: autologous-cultured adipose-derived mesenchymal stem cells outperform stromal vascular fraction: a systematic review and meta-analysis
Analysed 31 studies with 1,406 patients: cultured ADMSCs reduced pain from month 3, whereas SVF reached significance only at 12 months.
- 2024
- South Korea
- n = 1406