Research database
SVF Research Library
Search 52,792 real PubMed studies on SVF and adipose-derived stem cells — 36 matching records.
36 results — page 1 of 2
- Level DAnimal StudyEurope PMC
miR-432 Exacerbates Obesity-Induced Dysregulation of Glucose and Lipid Homeostasis
Animal Study on Type 2 Diabetes, published in Diabetes (2026) — summary generated from the PubMed abstract.
- 2026
Diabetes1 citations - Level DAnimal StudyEurope PMC
Annexin A1 exacerbates islet stellate cell activation by regulating triglyceride catabolism via the PPARα/ACOX1/CYP4a pathway
Animal Study on Systemic / IV, published in Islets (2026) — summary generated from the PubMed abstract.
- 2026
Islets - Level CProspective StudyEurope PMC
The exosomal miR-26b-3p derived from Crohn's disease-associated mesenteric adipose tissue induces M1 macrophage polarization and exacerbates ileocolonic anastomosis inflammation via the p38-MAPK signaling pathway
Prospective Study on Chronic Inflammation, Autoimmune Research, published in Front Immunol (2026) — summary generated from the PubMed abstract.
- 2026
Front Immunol1 citations - Level DAnimal StudyEurope PMC
Ash2l deficiency impairs adipose tissue thermogenesis and exacerbates obesity in mice
Animal Study on Hair & Scalp, Hip, Systemic / IV, published in Cell Mol Biol Lett (2026) — summary generated from the PubMed abstract.
- 2026
Cell Mol Biol Lett - Level DAnimal StudyEurope PMC
IDH3A Deficiency Compromises Adaptive Thermogenesis and Exacerbates Obesity-Induced Metabolic Dysfunction via Impaired BCKDHA-Dependent BCAA Catabolism
Animal Study, published in Diabetes (2026) — summary generated from the PubMed abstract.
- 2026
Diabetes - Level DAnimal StudyEurope PMC
Adipose tissue inflammation mediated by CCL19 overexpression exacerbates experimental periodontitis via elevated circulating saturated fatty acids and osteopontin in Western-diet-fed mice
Animal Study, published in Front Immunol (2026) — summary generated from the PubMed abstract.
- 2026
Front Immunol - Level CProspective StudyPubMed
Serum Leptin Exacerbates Osteoarthritis by Promoting Subchondral Bone H-Type Vessel Angiogenesis via Activation of the PI3K/AKT Pathway.
Prospective Study on Knee Osteoarthritis, Osteoarthritis, Cartilage Damage, published in J Cell Mol Med (2026) — summary generated from the PubMed abstract.
- 2026
J Cell Mol Med - Level DLaboratory StudyEurope PMC
CIDEC/FSP27 exacerbates obesity-related abdominal aortic aneurysm by promoting perivascular adipose tissue inflammation
Laboratory Study, published in Life Metab (2025) — summary generated from the PubMed abstract.
- 2025
Life Metab6 citations - Level DAnimal StudyEurope PMC
Deleting adipose FXR exacerbates metabolic defects and induces endocannabinoid lipid, 2-oleoyl glycerol, in obesity
Animal Study on Systemic / IV, published in J Lipid Res (2025) — summary generated from the PubMed abstract.
- 2025
J Lipid Res3 citations - Level CProspective StudyEurope PMC
ITIH5-mediated fibroblast/macrophage crosstalk exacerbates cardiac remodelling after myocardial infarction
Prospective Study with a reported sample of 53 on Cardiovascular Disease, published in J Transl Med (2025) — summary generated from the PubMed abstract.
- 2025
- n = 53
J Transl Med5 citations - Level DLaboratory StudyEurope PMC
Saturated fat exacerbates mitochondrial dysfunction through remodelling of ATP production and inflammation in Barrett's oesophagus compared to monounsaturated fat, particularly in contrast to oesophageal adenocarcinoma
Laboratory Study, published in Neoplasia (2025) — summary generated from the PubMed abstract.
- 2025
Neoplasia - Level DAnimal StudyEurope PMC
Mechanical Stretch-Induced Interlayer Coordination between MMP2 and COL17A1 Exacerbates Regenerative Exhaustion in Skin
Animal Study, published in Adv Sci (Weinh) (2025) — summary generated from the PubMed abstract.
- 2025
Adv Sci (Weinh)4 citations - Level DAnimal StudyEurope PMC
TIGAR exacerbates obesity by triggering LRRK2-mediated defects in macroautophagy and chaperone-mediated autophagy in adipocytes
Animal Study, published in Autophagy (2024) — summary generated from the PubMed abstract.
- 2024
Autophagy15 citations - Level DAnimal StudyEurope PMC
Adipose-targeted SWELL1 deletion exacerbates obesity- and age-related nonalcoholic fatty liver disease
Animal Study on Type 2 Diabetes, published in JCI Insight (2023) — summary generated from the PubMed abstract.
- 2023
JCI Insight10 citations - Level DAnimal StudyEurope PMC
Social isolation exacerbates diet-induced obesity and peripheral inflammation in young male mice under thermoneutrality
Animal Study on Chronic Inflammation, published in iScience (2023) — summary generated from the PubMed abstract.
- 2023
iScience22 citations - Level DAnimal StudyEurope PMC
Endothelial AMPKα1/PRKAA1 exacerbates inflammation in HFD-fed mice
Animal Study on Type 2 Diabetes, published in Br J Pharmacol (2022) — summary generated from the PubMed abstract.
- 2022
Br J Pharmacol13 citations - Level CProspective StudyPubMed
Low-dose mesenchymal stem cell therapy for discogenic pain: safety and efficacy results from a 1-year feasibility study.
Prospective Study on Back Pain, Disc Degeneration, published in Future Sci OA (2022) — summary generated from the PubMed abstract.
- 2022
Future Sci OA13 citations - Level DAnimal StudyEurope PMC
Early life stress exacerbates obesity in adult female mice via mineralocorticoid receptor-dependent increases in adipocyte triglyceride and glycerol content
Animal Study, published in Life Sci (2022) — summary generated from the PubMed abstract.
- 2022
Life Sci14 citations - Level DAnimal StudyEurope PMC
Loss of myeloid lipoprotein lipase exacerbates adipose tissue fibrosis with collagen VI deposition and hyperlipidemia in leptin-deficient obese mice
Animal Study, published in J Biol Chem (2022) — summary generated from the PubMed abstract.
- 2022
J Biol Chem3 citations - Level DAnimal StudyEurope PMC
The adipocyte-enriched secretory protein tetranectin exacerbates type 2 diabetes by inhibiting insulin secretion from β cells
Animal Study on Type 2 Diabetes, published in Sci Adv (2022) — summary generated from the PubMed abstract.
- 2022
Sci Adv11 citations - Level DAnimal StudyEurope PMC
ACE2 deficiency exacerbates obesity-related glomerulopathy through its role in regulating lipid metabolism
Animal Study on Chronic Inflammation, published in Cell Death Discov (2022) — summary generated from the PubMed abstract.
- 2022
Cell Death Discov7 citations - Level DAnimal StudyEurope PMC
Osteopontin Exacerbates High-Fat Diet-Induced Metabolic Disorders in a Microbiome-Dependent Manner
Animal Study, published in mBio (2022) — summary generated from the PubMed abstract.
- 2022
mBio13 citations - Level DAnimal StudyEurope PMC
The obesity-induced adipokine sST2 exacerbates adipose T<sub>reg</sub> and ILC2 depletion and promotes insulin resistance
Animal Study on Type 2 Diabetes, published in Sci Adv (2020) — summary generated from the PubMed abstract.
- 2020
Sci Adv59 citations - Level DAnimal StudyEurope PMC
Lack of the E3 Ubiquitin Ligase March1 Affects CD8 T Cell Fate and Exacerbates Insulin Resistance in Obese Mice
Animal Study on Type 2 Diabetes, published in Front Immunol (2020) — summary generated from the PubMed abstract.
- 2020
Front Immunol5 citations
In-depth reviewed studies (full Thai translation)
Evidence system- Level ARandomized Controlled Trial
Cell-based versus corticosteroid injections for knee pain in osteoarthritis: a randomized phase 3 trial
A multicentre randomized trial in 480 knee osteoarthritis patients comparing SVF, BMAC and umbilical cord MSCs against corticosteroid injection. At 12 months no cell product outperformed the steroid control.
- 2023
- United States
- n = 480
- Level AMeta-analysis
Intra-articular Injection of Autologous Adipose-Derived Stem Cells or Stromal Vascular Fractions: Are They Effective for Patients With Knee Osteoarthritis? A Systematic Review With Meta-analysis of Randomized Controlled Trials
Pooled five RCTs comparing ADSC/SVF injection with placebo or hyaluronic acid, finding significant pain and function improvement at 6 and 12 months.
- 2023
- South Korea
- Level AMeta-analysis
Rapid-acting pain relief in knee osteoarthritis: autologous-cultured adipose-derived mesenchymal stem cells outperform stromal vascular fraction: a systematic review and meta-analysis
Analysed 31 studies with 1,406 patients: cultured ADMSCs reduced pain from month 3, whereas SVF reached significance only at 12 months.
- 2024
- South Korea
- n = 1406