Research database
SVF Research Library
Search 52,792 real PubMed studies on SVF and adipose-derived stem cells — 36 matching records.
36 results — page 1 of 2
- Level DLaboratory StudyEurope PMC
TSG-6 Activated MSC-derived Extracellular Vesicles Present Altered micro-RNA Contents and Ameliorate the Inflammatory Phenotype of Macrophages in Vitro
Laboratory Study with a reported sample of 11 on Chronic Inflammation, Immune Modulation, published in Inflammation (2026) — summary generated from the PubMed abstract.
- 2026
- n = 11
Inflammation - Level DAnimal StudyPubMed
Synovial inflammatory macrophage-derived extracellular vesicles exacerbate cartilage lesions with a FMRP-selectively sorted manner in osteoarthritis.
Animal Study on Osteoarthritis, published in Bone Res (2026) — summary generated from the PubMed abstract.
- 2026
Bone Res - Level DAnimal StudyPubMed
Extracellular vesicles from TNF-α and TGF-β1-treated ADSCs promote tissue-engineered cartilage regeneration by modulating macrophages via the miR-378a-3p/SIRPα axis.
Animal Study on Cartilage Damage, Immune Modulation, published in Stem Cell Res Ther (2026) — summary generated from the PubMed abstract.
- 2026
Stem Cell Res Ther1 citations - Level DAnimal StudyEurope PMC
Adipose extracellular vesicles carrying miR-210-3p drive macrophage inflammation and nicotine-induced atherosclerosis
Animal Study on Chronic Inflammation, published in iScience (2026) — summary generated from the PubMed abstract.
- 2026
iScience - Level DNarrative ReviewEurope PMC
Macrophage Extracellular Vesicles: Therapeutic Strategies for Corneal Fibrosis in Rare Diseases
Narrative Review on Scar, Chronic Inflammation, Immune Modulation, published in Biomolecules (2026) — summary generated from the PubMed abstract.
- 2026
Biomolecules - Level DAnimal StudyPubMed
ASC-Derived Extracellular Vesicles Suppress Macrophage-Driven Inflammatory Amplification and Contractile Activation of Uterine Smooth Muscle Cells.
Animal Study, published in Int J Mol Sci (2026) — summary generated from the PubMed abstract.
- 2026
Int J Mol Sci - Level DAnimal StudyPubMed
Adipose-derived mesenchymal stem cell-derived extracellular vesicles reduce glycolysis and polarize macrophages toward M2 phenotype in sepsis-associated acute kidney injury via the miR-574-5p/GLUT1 axis.
Animal Study on Acute Kidney Injury, Chronic Inflammation, published in Clin Exp Med (2026) — summary generated from the PubMed abstract.
- 2026
Clin Exp Med - Level DAnimal StudyEurope PMC
Bone-Targeting Microspheres Enable Sustained Release of CD301b<sup>+</sup> Macrophage-Derived Small Extracellular Vesicles to Promote Bone Repair
Animal Study on Immune Modulation, published in Theranostics (2026) — summary generated from the PubMed abstract.
- 2026
Theranostics - Level DLaboratory StudyPubMed
Immunometabolic reprogramming of macrophages by miR-423-5p-enriched small extracellular vesicles delivered via glucose/ROS-responsive hydrogel for diabetic wound healing.
Laboratory Study on Diabetic Foot, Chronic Wound, Chronic Inflammation, Immune Modulation, published in J Nanobiotechnology (2026) — summary generated from the PubMed abstract.
- 2026
J Nanobiotechnology - Level DAnimal StudyPubMed
The equine mesenchymal stromal cell (MSC) secretome modulates neutrophils and monocyte-derived macrophages and extracellular vesicles (EVs) impact macrophage viability.
Animal Study, published in Vet Immunol Immunopathol (2026) — summary generated from the PubMed abstract.
- 2026
Vet Immunol Immunopathol - Level DLaboratory StudyEurope PMC
Small extracellular vesicles derived from auricular chondrocytes promote secretion of interleukin 10 in bone marrow M1-like macrophages
Laboratory Study on Cartilage Damage, Chronic Inflammation, published in Regen Ther (2025) — summary generated from the PubMed abstract.
- 2025
Regen Ther2 citations - Level DAnimal StudyPubMed
Adipose progenitor cell-derived extracellular vesicles suppress macrophage M1 program to alleviate midlife obesity.
Animal Study, published in Nat Commun (2025) — summary generated from the PubMed abstract.
- 2025
Nat Commun12 citations - Level DNarrative ReviewEurope PMC
Extracellular Vesicles in Renal Inflammatory Diseases: Revealing Mechanisms of Extracellular Vesicle-Mediated Macrophage Regulation
Narrative Review on Chronic Kidney Disease, Acute Kidney Injury, published in Int J Mol Sci (2025) — summary generated from the PubMed abstract.
- 2025
Int J Mol Sci2 citations - Level DAnimal StudyPubMed
Mechanism of adipose-derived stem cell-derived extracellular vesicles affecting macrophage efferocytosis by mediating ADAM17/MerTK in the apoptosis of tubular epithelial cells after sepsis-associated acute kidney injury.
Animal Study on Acute Kidney Injury, published in Transl Res (2025) — summary generated from the PubMed abstract.
- 2025
Transl Res - Level BClinical TrialEurope PMC
Adipose Tissue Macrophages as Initiators of Exacerbated Periodontitis in Estrogen-Deficient Environments via the Amplifier Extracellular Vesicles
Clinical Trial on Systemic / IV, published in Adv Sci (Weinh) (2025) — summary generated from the PubMed abstract.
- 2025
Adv Sci (Weinh)6 citations - Level DNarrative ReviewEurope PMC
The crosstalk among macrophages, chondrocytes and mesenchymal stem cells in osteoarthritis: the role of extracellular vesicles
Narrative Review on Osteoarthritis, Cartilage Damage, published in Stem Cell Res Ther (2025) — summary generated from the PubMed abstract.
- 2025
Stem Cell Res Ther2 citations - Level CProspective StudyPubMed
Adipose-derived MSC extracellular vesicles ameliorate sepsis by reprogramming macrophages via miR-21-5p targeting PELI1 .
Prospective Study on Immune Modulation, published in Biomol Biomed (2025) — summary generated from the PubMed abstract.
- 2025
Biomol Biomed3 citations - Level DAnimal StudyEurope PMC
Hypoxia-Induced Extracellular Vesicles Derived from Human Umbilical Cord Mesenchymal Stem Cells Regulate Macrophage Polarization and Enhance Angiogenesis to Promote Diabetic Wound Healing
Animal Study on Diabetic Foot, Chronic Wound, Chronic Inflammation, published in Biomolecules (2025) — summary generated from the PubMed abstract.
- 2025
Biomolecules4 citations - Level DNarrative ReviewEurope PMC
Extracellular vesicles for macrophage reprogramming: an emerging paradigm in immunomodulatory therapeutics
Narrative Review on Chronic Inflammation, Immune Modulation, published in J Biol Eng (2025) — summary generated from the PubMed abstract.
- 2025
J Biol Eng5 citations - Level DLaboratory StudyPubMed
Transfer of inflammatory mitochondria via extracellular vesicles from M1 macrophages induces ferroptosis of pancreatic beta cells in acute pancreatitis.
Laboratory Study, published in J Extracell Vesicles (2024) — summary generated from the PubMed abstract.
- 2024
J Extracell Vesicles53 citations - Level DNarrative ReviewEurope PMC
Extracellular vesicles as carriers for noncoding RNA-based regulation of macrophage/microglia polarization: an emerging candidate regulator for lung and traumatic brain injuries
Narrative Review on Chronic Inflammation, published in Front Immunol (2024) — summary generated from the PubMed abstract.
- 2024
Front Immunol6 citations - Level DAnimal StudyEurope PMC
Macrophage-derived extracellular vesicles represent a promising endogenous iron-chelating therapy for iron overload and cardiac injury in myocardial infarction
Animal Study on Cardiovascular Disease, published in J Nanobiotechnology (2024) — summary generated from the PubMed abstract.
- 2024
J Nanobiotechnology12 citations - Level DAnimal StudyPubMed
Macrophage heterogeneity regulation by small extracellular vesicles from adipose-derived stem cells: A promising approach for treating chronic prostatitis/pelvic pain syndrome.
Animal Study on Chronic Inflammation, published in Biomater Adv (2024) — summary generated from the PubMed abstract.
- 2024
Biomater Adv5 citations - Level DNarrative ReviewEurope PMC
Tools for regulating metabolic diseases: extracellular vesicles from adipose macrophages
Narrative Review on Type 2 Diabetes, published in Front Endocrinol (Lausanne) (2024) — summary generated from the PubMed abstract.
- 2024
Front Endocrinol (Lausanne)
In-depth reviewed studies (full Thai translation)
Evidence system- Level ARandomized Controlled Trial
Cell-based versus corticosteroid injections for knee pain in osteoarthritis: a randomized phase 3 trial
A multicentre randomized trial in 480 knee osteoarthritis patients comparing SVF, BMAC and umbilical cord MSCs against corticosteroid injection. At 12 months no cell product outperformed the steroid control.
- 2023
- United States
- n = 480
- Level AMeta-analysis
Intra-articular Injection of Autologous Adipose-Derived Stem Cells or Stromal Vascular Fractions: Are They Effective for Patients With Knee Osteoarthritis? A Systematic Review With Meta-analysis of Randomized Controlled Trials
Pooled five RCTs comparing ADSC/SVF injection with placebo or hyaluronic acid, finding significant pain and function improvement at 6 and 12 months.
- 2023
- South Korea
- Level AMeta-analysis
Rapid-acting pain relief in knee osteoarthritis: autologous-cultured adipose-derived mesenchymal stem cells outperform stromal vascular fraction: a systematic review and meta-analysis
Analysed 31 studies with 1,406 patients: cultured ADMSCs reduced pain from month 3, whereas SVF reached significance only at 12 months.
- 2024
- South Korea
- n = 1406