Research database
SVF Research Library
Search 52,792 real PubMed studies on SVF and adipose-derived stem cells — 69 matching records.
69 results — page 1 of 3
- Level DAnimal StudyPubMed
Extracellular vesicles derived from adipose-derived mesenchymal stem/stromal cells prevent synovial inflammation and attenuate cartilage degeneration in rodent osteoarthritis.
Animal Study on Osteoarthritis, Cartilage Damage, Chronic Inflammation, Immune Modulation, published in Regen Ther (2026) — summary generated from the PubMed abstract.
- 2026
Regen Ther - Level BRandomized Controlled TrialPubMed
Intra-articular allogeneic adipose-derived mesenchymal stromal cell injections for stage III knee osteoarthritis: a double-blind placebo-controlled trial with 60-month follow-up.
Randomized Controlled Trial with a reported sample of 29 on Knee Osteoarthritis, Osteoarthritis, Cartilage Damage, published in Stem Cells Transl Med (2026) — summary generated from the PubMed abstract.
- 2026
- n = 29
Stem Cells Transl Med - Level DNarrative ReviewEurope PMC
Mesenchymal Stromal Cells in Knee Osteoarthritis: A Review of Nomenclature, Criteria, and Therapeutic Mechanisms
Narrative Review on Knee Osteoarthritis, Osteoarthritis, Immune Modulation, published in Ther Clin Risk Manag (2026) — summary generated from the PubMed abstract.
- 2026
Ther Clin Risk Manag - Level DLaboratory StudyPubMed
Early histological advantage of CD271-positive adipose-derived mesenchymal stromal cells isolated from the infrapatellar fat pad in experimental knee osteoarthritis.
Laboratory Study on Knee Osteoarthritis, Osteoarthritis, Chronic Inflammation, Immune Modulation, published in BMC Musculoskelet Disord (2026) — summary generated from the PubMed abstract.
- 2026
BMC Musculoskelet Disord - Level AMeta-analysisPubMed
Autologous adipose-derived mesenchymal stromal cell injection for knee osteoarthritis improves pain and function without a clear increase in adverse events: A systematic review and meta-analysis of randomized controlled
Meta-analysis with a reported sample of 551 on Knee Osteoarthritis, Osteoarthritis, published in Knee Surg Sports Traumatol Arthrosc (2026) — summary generated from the PubMed abstract.
- 2026
- n = 551
Knee Surg Sports Traumatol Arthrosc - Level DLaboratory StudyPubMed
Simple Isolation of Human Bone Marrow Adipose Tissue-Derived Mesenchymal Stem/Stromal Cells.
Laboratory Study on Knee, Hip, published in Curr Protoc (2025) — summary generated from the PubMed abstract.
- 2025
Curr Protoc - Level ASystematic ReviewPubMed
Evaluation of Spin in Clinical Trials of Mesenchymal Stromal Cells for the Treatment of Knee Osteoarthritis: A Systematic Review.
Systematic Review on Knee Osteoarthritis, Osteoarthritis, published in Am J Sports Med (2025) — summary generated from the PubMed abstract.
- 2025
Am J Sports Med - Level AMeta-analysisPubMed
Intra-articular Stromal Vascular Fraction and Mesenchymal Stem Cell Injections Show Variable Efficacy and Higher Potential Complications Compared to Corticosteroid and Hyaluronic Acid in Treatment of Knee Osteoarthritis:
Meta-analysis with a reported sample of 671 on Knee Osteoarthritis, Osteoarthritis, published in Arthroscopy (2025) — summary generated from the PubMed abstract.
- 2025
- n = 671
Arthroscopy4 citations - Level BClinical TrialPubMed
A Narrative Review on Manufacturing Methods Employed in the Production of Mesenchymal Stromal Cells for Knee Osteoarthritis Therapy.
Clinical Trial on Knee Osteoarthritis, Osteoarthritis, Immune Modulation, published in Biomedicines (2025) — summary generated from the PubMed abstract.
- 2025
Biomedicines1 citations - Level DLaboratory StudyPubMed
Characterization of Extracellular Vesicles from Infrapatellar Fat Pad Mesenchymal Stem/Stromal Cells Expanded Using Regulatory-Compliant Media and Inflammatory/Hormonal Priming.
Laboratory Study on Osteoarthritis, Cartilage Damage, Chronic Inflammation, Immune Modulation, published in Cells (2025) — summary generated from the PubMed abstract.
- 2025
Cells - Level BRandomized Controlled TrialPubMed
Effect of intra-articular adipose-derived mesenchymal stromal cell versus placebo injection on pain and function in patients with knee osteoarthritis: the ADIPOA2 phase 2b randomised clinical trial.
Randomized Controlled Trial with a reported sample of 26 on Knee Osteoarthritis, Osteoarthritis, published in Ann Rheum Dis (2025) — summary generated from the PubMed abstract.
- 2025
- n = 26
Ann Rheum Dis - Level BClinical TrialPubMed
Allogeneic mesenchymal stromal cell injections for knee osteoarthritis: a review of clinical outcomes.
Clinical Trial with a reported sample of 11 on Knee Osteoarthritis, Osteoarthritis, published in Regen Med (2025) — summary generated from the PubMed abstract.
- 2025
- n = 11
Regen Med - Level DAnimal StudyPubMed
Functional Assessment of Genetically Modified Infrapatellar Fat Pad Mesenchymal Stem/Stromal Cell-Derived Extracellular Vesicles (EVs): Potential Implications for Inflammation/Pain Reversal in Osteoarthritis.
Animal Study on Osteoarthritis, Cartilage Damage, Neuroinflammation, Chronic Inflammation, published in Cells (2025) — summary generated from the PubMed abstract.
- 2025
Cells - Level CProspective StudyPubMed
Culture of Hoffa fat pad mesenchymal stem/stromal cells on microcarrier suspension in vertical wheel bioreactor for extracellular vesicle production.
Prospective Study on Osteoarthritis, Chronic Inflammation, Immune Modulation, published in Stem Cell Res Ther (2024) — summary generated from the PubMed abstract.
- 2024
Stem Cell Res Ther11 citations - Level BClinical TrialPubMed
Comparison studies identify mesenchymal stromal cells with potent regenerative activity in osteoarthritis treatment.
Clinical Trial on Knee Osteoarthritis, Osteoarthritis, Immune Modulation, published in NPJ Regen Med (2024) — summary generated from the PubMed abstract.
- 2024
NPJ Regen Med4 citations - Level ASystematic ReviewEurope PMC
Compliance with requirements for registration and reporting of results in trials of mesenchymal stromal cells for musculoskeletal disorders: a systematic review
Systematic Review with a reported sample of 993 on Knee Osteoarthritis, Osteoarthritis, published in BMJ Open (2024) — summary generated from the PubMed abstract.
- 2024
- n = 993
BMJ Open - Level BRandomized Controlled TrialEurope PMC
Evaluation of Patellar Tendon Structural Changes following Biological Treatments: Secondary Analysis of Double-Blinded Clinical Trial of Bone Marrow Mesenchymal Stromal Cells and Leukocyte-Poor Platelet-Rich Plasma
Randomized Controlled Trial on Tendon Injury, published in Biomedicines (2024) — summary generated from the PubMed abstract.
- 2024
Biomedicines3 citations - Level AMeta-analysisEurope PMC
Advanced therapy with mesenchymal stromal cells for knee osteoarthritis: Systematic review and meta-analysis of randomized controlled trials
Meta-analysis with a reported sample of 1048 on Knee Osteoarthritis, Osteoarthritis, Cartilage Damage, published in J Orthop Translat (2024) — summary generated from the PubMed abstract.
- 2024
- n = 1048
J Orthop Translat4 citations - Level AMeta-analysisPubMed
Rapid-acting pain relief in knee osteoarthritis: autologous-cultured adipose-derived mesenchymal stem cells outperform stromal vascular fraction: a systematic review and meta-analysis.
Meta-analysis with a reported sample of 406 on Knee Osteoarthritis, Osteoarthritis, Cartilage Damage, published in Stem Cell Res Ther (2024) — summary generated from the PubMed abstract.
- 2024
- n = 406
Stem Cell Res Ther6 citations - Level DLaboratory StudyPubMed
The roles of regulatory-compliant media and inflammatory/oxytocin priming selection in enhancing human mesenchymal stem/stromal cell immunomodulatory properties.
Laboratory Study on Osteoarthritis, Chronic Inflammation, Immune Modulation, published in Sci Rep (2024) — summary generated from the PubMed abstract.
- 2024
Sci Rep - Level AMeta-analysisPubMed
Comparative effectiveness of adipose-derived mesenchymal stromal cells in the management of knee osteoarthritis: A meta-analysis.
Meta-analysis with a reported sample of 936 on Knee Osteoarthritis, Osteoarthritis, Cartilage Damage, published in World J Orthop (2023) — summary generated from the PubMed abstract.
- 2023
- n = 936
World J Orthop36 citations - Level BClinical TrialPubMed
Cartilage regeneration and inflammation modulation in knee osteoarthritis following injection of allogeneic adipose-derived mesenchymal stromal cells: a phase II, triple-blinded, placebo controlled, randomized trial.
Clinical Trial with a reported sample of 40 on Knee Osteoarthritis, Osteoarthritis, Cartilage Damage, Immune Modulation, published in Stem Cell Res Ther (2023) — summary generated from the PubMed abstract.
- 2023
- n = 40
Stem Cell Res Ther70 citations - Level DAnimal StudyPubMed
Small extracellular vesicles derived from human adipose-derived mesenchymal stromal cells cultured in a new chemically-defined contaminate-free media exhibit enhanced biological and therapeutic effects on human chondrocy
Animal Study on Knee Osteoarthritis, Osteoarthritis, Cartilage Damage, published in J Extracell Vesicles (2023) — summary generated from the PubMed abstract.
- 2023
J Extracell Vesicles24 citations - Level CRetrospective StudyPubMed
Adipose-Derived Stromal Vascular Fractions Are Comparable With Allogenic Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells as a Supplementary Strategy of High Tibial Osteotomy for Varus Knee Osteoarthritis.
Retrospective Study with a reported sample of 25 on Knee Osteoarthritis, Osteoarthritis, Cartilage Damage, published in Arthrosc Sports Med Rehabil (2023) — summary generated from the PubMed abstract.
- 2023
- n = 25
Arthrosc Sports Med Rehabil10 citations
In-depth reviewed studies (full Thai translation)
Evidence system- Level ARandomized Controlled Trial
Cell-based versus corticosteroid injections for knee pain in osteoarthritis: a randomized phase 3 trial
A multicentre randomized trial in 480 knee osteoarthritis patients comparing SVF, BMAC and umbilical cord MSCs against corticosteroid injection. At 12 months no cell product outperformed the steroid control.
- 2023
- United States
- n = 480
- Level AMeta-analysis
Intra-articular Injection of Autologous Adipose-Derived Stem Cells or Stromal Vascular Fractions: Are They Effective for Patients With Knee Osteoarthritis? A Systematic Review With Meta-analysis of Randomized Controlled Trials
Pooled five RCTs comparing ADSC/SVF injection with placebo or hyaluronic acid, finding significant pain and function improvement at 6 and 12 months.
- 2023
- South Korea
- Level AMeta-analysis
Rapid-acting pain relief in knee osteoarthritis: autologous-cultured adipose-derived mesenchymal stem cells outperform stromal vascular fraction: a systematic review and meta-analysis
Analysed 31 studies with 1,406 patients: cultured ADMSCs reduced pain from month 3, whereas SVF reached significance only at 12 months.
- 2024
- South Korea
- n = 1406