Research database
SVF Research Library
Search 52,792 real PubMed studies on SVF and adipose-derived stem cells — 43 matching records.
43 results — page 1 of 2
- Level CProspective StudyPubMed
[Exosomes from folic acid-treated subpatellar fat pad-derived mesenchymal stem cells promote M2 polarization of macrophages in vitro ].
Prospective Study on Knee Osteoarthritis, Osteoarthritis, published in Nan Fang Yi Ke Da Xue Xue Bao (2026) — summary generated from the PubMed abstract.
- 2026
Nan Fang Yi Ke Da Xue Xue Bao - Level DAnimal StudyPubMed
Gluteal adipose-derived stem cell exosomes promote macrophage polarization and cartilage regeneration in osteoarthritis via PTPRC modulation.
Animal Study on Osteoarthritis, Cartilage Damage, Meniscus Injury, Chronic Inflammation, published in Biomed Pharmacother (2026) — summary generated from the PubMed abstract.
- 2026
Biomed Pharmacother - Level ASystematic ReviewEurope PMC
Exosomes as Cellular Communicators and Therapeutic Agents in Orthopedic Diseases: From Mechanisms to Intervention
Systematic Review on Osteoarthritis, Chronic Inflammation, published in Int J Nanomedicine (2026) — summary generated from the PubMed abstract.
- 2026
Int J Nanomedicine1 citations - Level DAnimal StudyPubMed
Exosomes secreted by ADMSCs preserve cartilage integrity in knee osteoarthritis via AMPK-mediated mitochondrial dynamics and apoptosis.
Animal Study on Knee Osteoarthritis, Osteoarthritis, published in Stem Cells (2026) — summary generated from the PubMed abstract.
- 2026
Stem Cells - Level DLaboratory StudyEurope PMC
Exosomes Derived From Mesenchymal Stem Cells Regulating Myotube Cell Atrophy via NF-κB Signaling Pathway
Laboratory Study on Osteoarthritis, published in Stem Cells Int (2026) — summary generated from the PubMed abstract.
- 2026
Stem Cells Int - Level DNarrative ReviewPubMed
Exosomes in bone health and disease: cellular crosstalk, systemic signaling, and AI-driven advances in regenerative therapy.
Narrative Review on Osteoarthritis, published in Stem Cell Res Ther (2026) — summary generated from the PubMed abstract.
- 2026
Stem Cell Res Ther - Level DLaboratory StudyEurope PMC
The effect of exosomes from canine bone mesenchymal stem cells on IL-1β-mediated inflammatory responses in chondrocytes
Laboratory Study on Osteoarthritis, Chronic Inflammation, published in Cytotechnology (2025) — summary generated from the PubMed abstract.
- 2025
Cytotechnology1 citations - Level DNarrative ReviewEurope PMC
Exosomes of stem cells: a potential frontier in the treatment of osteoarthritis
Narrative Review on Osteoarthritis, published in Precis Clin Med (2025) — summary generated from the PubMed abstract.
- 2025
Precis Clin Med3 citations - Level DNarrative ReviewEurope PMC
Pyroptosis: candidate key targets for mesenchymal stem cell-derived exosomes for the treatment of bone-related diseases
Narrative Review on Osteoarthritis, Spinal Cord Injury, published in Stem Cell Res Ther (2025) — summary generated from the PubMed abstract.
- 2025
Stem Cell Res Ther7 citations - Level DAnimal StudyPubMed
tsRNA-12391-Modified Adipose Mesenchymal Stem Cell-Derived Exosomes Mitigate Cartilage Degeneration in Osteoarthritis by Enhancing Mitophagy.
Animal Study on Osteoarthritis, published in Biotechnol J (2025) — summary generated from the PubMed abstract.
- 2025
Biotechnol J - Level BRandomized Controlled TrialEurope PMC
Injection of human umbilical cord mesenchymal stem cells exosomes for the treatment of knee osteoarthritis: from preclinical to clinical research
Randomized Controlled Trial on Knee Osteoarthritis, Osteoarthritis, Cartilage Damage, Chronic Inflammation, published in J Transl Med (2025) — summary generated from the PubMed abstract.
- 2025
J Transl Med23 citations - Level AMeta-analysisEurope PMC
Mesenchymal stem cell-derived exosomes for the treatment of knee osteoarthritis: a systematic review and meta-analysis based on rat model
Meta-analysis on Knee Osteoarthritis, Osteoarthritis, Cartilage Damage, Chronic Inflammation, published in Front Pharmacol (2025) — summary generated from the PubMed abstract.
- 2025
Front Pharmacol2 citations - Level DAnimal StudyPubMed
Comparative Efficacy of Exosomes Derived from Different Mesenchymal Stem Cell Sources in Osteoarthritis Models: An In Vitro and Ex Vivo Analysis.
Animal Study on Osteoarthritis, Cartilage Damage, Chronic Inflammation, published in Int J Mol Sci (2025) — summary generated from the PubMed abstract.
- 2025
Int J Mol Sci6 citations - Level ASystematic ReviewEurope PMC
The role of synovial mesenchymal stem cell-derived exosomes in cartilage repair: a systematic review
Systematic Review on Knee Osteoarthritis, Osteoarthritis, Cartilage Damage, published in Front Pharmacol (2025) — summary generated from the PubMed abstract.
- 2025
Front Pharmacol2 citations - Level DAnimal StudyPubMed
Adipose Mesenchymal Stem Cells Derived Exosomes Ameliorates KOA Cartilage Damage and Inflammation by Activation of PINK1-Mediated Mitochondrial Autophagy.
Animal Study on Knee Osteoarthritis, Osteoarthritis, Ligament Injury, published in FASEB J (2025) — summary generated from the PubMed abstract.
- 2025
FASEB J3 citations - Level DNarrative ReviewEurope PMC
Stem Cell Exosomes for Osteoarthritis in Veterinary Medicine
Narrative Review on Osteoarthritis, Cartilage Damage, published in Stem Cells Int (2025) — summary generated from the PubMed abstract.
- 2025
Stem Cells Int - Level DAnimal StudyPubMed
NMN-primed exosomes derived from infrapatellar fat pad mesenchymal stem cells exert synergistic anti-inflammatory and cartilage-protective effects via MERTK pathway activation in knee osteoarthritis.
Animal Study on Knee Osteoarthritis, Osteoarthritis, Cartilage Damage, Chronic Inflammation, published in Int J Pharm (2025) — summary generated from the PubMed abstract.
- 2025
Int J Pharm - Level BClinical TrialPubMed
The future of osteoarthritis treatment: exploring the potential of exosomes from adipose tissue-derived stem cells : a scoping review.
Clinical Trial on Osteoarthritis, Cartilage Damage, Chronic Inflammation, published in Bone Joint Res (2025) — summary generated from the PubMed abstract.
- 2025
Bone Joint Res - Level DNarrative ReviewEurope PMC
Exosomes Reshape the Osteoarthritic Defect: Emerging Potential in Regenerative Medicine-A Review
Narrative Review on Osteoarthritis, Cartilage Damage, Chronic Inflammation, published in Int J Stem Cells (2024) — summary generated from the PubMed abstract.
- 2024
Int J Stem Cells5 citations - Level DNarrative ReviewEurope PMC
Exosomes derived from MSC as drug system in osteoarthritis therapy
Narrative Review on Osteoarthritis, published in Front Bioeng Biotechnol (2024) — summary generated from the PubMed abstract.
- 2024
Front Bioeng Biotechnol14 citations - Level DAnimal StudyEurope PMC
Cartilage stem/progenitor cells-derived exosomes facilitate knee cartilage repair in a subacute osteoarthritis rat model
Animal Study on Osteoarthritis, Cartilage Damage, published in J Cell Mol Med (2024) — summary generated from the PubMed abstract.
- 2024
J Cell Mol Med11 citations - Level DNarrative ReviewEurope PMC
Strategies in product engineering of mesenchymal stem cell-derived exosomes: unveiling the mechanisms underpinning the promotive effects of mesenchymal stem cell-derived exosomes
Narrative Review on Osteoarthritis, Cartilage Damage, published in Front Bioeng Biotechnol (2024) — summary generated from the PubMed abstract.
- 2024
Front Bioeng Biotechnol7 citations - Level DNarrative ReviewEurope PMC
Therapeutic potential of mesenchymal stem cell-derived exosomes in skeletal diseases
Narrative Review on Osteoarthritis, published in Front Mol Biosci (2024) — summary generated from the PubMed abstract.
- 2024
Front Mol Biosci14 citations - Level DLaboratory StudyEurope PMC
The Exosomes of Stem Cells from Human Exfoliated Deciduous Teeth Suppress Inflammation in Osteoarthritis
Laboratory Study on Osteoarthritis, Cartilage Damage, published in Int J Mol Sci (2024) — summary generated from the PubMed abstract.
- 2024
Int J Mol Sci5 citations
In-depth reviewed studies (full Thai translation)
Evidence system- Level ARandomized Controlled Trial
Cell-based versus corticosteroid injections for knee pain in osteoarthritis: a randomized phase 3 trial
A multicentre randomized trial in 480 knee osteoarthritis patients comparing SVF, BMAC and umbilical cord MSCs against corticosteroid injection. At 12 months no cell product outperformed the steroid control.
- 2023
- United States
- n = 480
- Level AMeta-analysis
Intra-articular Injection of Autologous Adipose-Derived Stem Cells or Stromal Vascular Fractions: Are They Effective for Patients With Knee Osteoarthritis? A Systematic Review With Meta-analysis of Randomized Controlled Trials
Pooled five RCTs comparing ADSC/SVF injection with placebo or hyaluronic acid, finding significant pain and function improvement at 6 and 12 months.
- 2023
- South Korea
- Level AMeta-analysis
Rapid-acting pain relief in knee osteoarthritis: autologous-cultured adipose-derived mesenchymal stem cells outperform stromal vascular fraction: a systematic review and meta-analysis
Analysed 31 studies with 1,406 patients: cultured ADMSCs reduced pain from month 3, whereas SVF reached significance only at 12 months.
- 2024
- South Korea
- n = 1406