Research database
SVF Research Library
Search 52,792 real PubMed studies on SVF and adipose-derived stem cells — 36 matching records.
36 results — page 1 of 2
- Level DAnimal StudyPubMed
Gluteal adipose-derived stem cell exosomes promote macrophage polarization and cartilage regeneration in osteoarthritis via PTPRC modulation.
Animal Study on Osteoarthritis, Cartilage Damage, Meniscus Injury, Chronic Inflammation, published in Biomed Pharmacother (2026) — summary generated from the PubMed abstract.
- 2026
Biomed Pharmacother - Level DNarrative ReviewEurope PMC
Exosomes: critical mediator and therapeutic target for osteoarthritis
Narrative Review on Osteoarthritis, Cartilage Damage, published in Am J Transl Res (2026) — summary generated from the PubMed abstract.
- 2026
Am J Transl Res - Level DAnimal StudyPubMed
Exosomes secreted by ADMSCs preserve cartilage integrity in knee osteoarthritis via AMPK-mediated mitochondrial dynamics and apoptosis.
Animal Study on Knee Osteoarthritis, Osteoarthritis, published in Stem Cells (2026) — summary generated from the PubMed abstract.
- 2026
Stem Cells - Level DNarrative ReviewEurope PMC
Potential and challenges of utilizing exosomes in osteoarthritis therapy (Review)
Narrative Review on Osteoarthritis, Cartilage Damage, published in Int J Mol Med (2025) — summary generated from the PubMed abstract.
- 2025
Int J Mol Med14 citations - Level DNarrative ReviewEurope PMC
Exosomes in cartilage microenvironment regulation and cartilage repair
Narrative Review on Osteoarthritis, Cartilage Damage, Scar, published in Front Cell Dev Biol (2025) — summary generated from the PubMed abstract.
- 2025
Front Cell Dev Biol7 citations - Level DAnimal StudyPubMed
tsRNA-12391-Modified Adipose Mesenchymal Stem Cell-Derived Exosomes Mitigate Cartilage Degeneration in Osteoarthritis by Enhancing Mitophagy.
Animal Study on Osteoarthritis, published in Biotechnol J (2025) — summary generated from the PubMed abstract.
- 2025
Biotechnol J - Level DNarrative ReviewEurope PMC
Research progress on exosomes from different sources in osteoarthritis and cartilage injury
Narrative Review on Osteoarthritis, published in J Orthop Surg Res (2025) — summary generated from the PubMed abstract.
- 2025
J Orthop Surg Res1 citations - Level BRandomized Controlled TrialEurope PMC
Injection of human umbilical cord mesenchymal stem cells exosomes for the treatment of knee osteoarthritis: from preclinical to clinical research
Randomized Controlled Trial on Knee Osteoarthritis, Osteoarthritis, Cartilage Damage, Chronic Inflammation, published in J Transl Med (2025) — summary generated from the PubMed abstract.
- 2025
J Transl Med23 citations - Level AMeta-analysisEurope PMC
Mesenchymal stem cell-derived exosomes for the treatment of knee osteoarthritis: a systematic review and meta-analysis based on rat model
Meta-analysis on Knee Osteoarthritis, Osteoarthritis, Cartilage Damage, Chronic Inflammation, published in Front Pharmacol (2025) — summary generated from the PubMed abstract.
- 2025
Front Pharmacol2 citations - Level DAnimal StudyPubMed
Comparative Efficacy of Exosomes Derived from Different Mesenchymal Stem Cell Sources in Osteoarthritis Models: An In Vitro and Ex Vivo Analysis.
Animal Study on Osteoarthritis, Cartilage Damage, Chronic Inflammation, published in Int J Mol Sci (2025) — summary generated from the PubMed abstract.
- 2025
Int J Mol Sci6 citations - Level ASystematic ReviewEurope PMC
The role of synovial mesenchymal stem cell-derived exosomes in cartilage repair: a systematic review
Systematic Review on Knee Osteoarthritis, Osteoarthritis, Cartilage Damage, published in Front Pharmacol (2025) — summary generated from the PubMed abstract.
- 2025
Front Pharmacol2 citations - Level DAnimal StudyPubMed
Adipose Mesenchymal Stem Cells Derived Exosomes Ameliorates KOA Cartilage Damage and Inflammation by Activation of PINK1-Mediated Mitochondrial Autophagy.
Animal Study on Knee Osteoarthritis, Osteoarthritis, Ligament Injury, published in FASEB J (2025) — summary generated from the PubMed abstract.
- 2025
FASEB J3 citations - Level DNarrative ReviewEurope PMC
Stem Cell Exosomes for Osteoarthritis in Veterinary Medicine
Narrative Review on Osteoarthritis, Cartilage Damage, published in Stem Cells Int (2025) — summary generated from the PubMed abstract.
- 2025
Stem Cells Int - Level DNarrative ReviewEurope PMC
Exosomes in Osteoarthritis: Breakthrough Innovations and Advanced Tissue Engineering for Cartilage Regeneration Since 2020
Narrative Review on Osteoarthritis, Cartilage Damage, published in Biomedicines (2025) — summary generated from the PubMed abstract.
- 2025
Biomedicines2 citations - Level DAnimal StudyPubMed
NMN-primed exosomes derived from infrapatellar fat pad mesenchymal stem cells exert synergistic anti-inflammatory and cartilage-protective effects via MERTK pathway activation in knee osteoarthritis.
Animal Study on Knee Osteoarthritis, Osteoarthritis, Cartilage Damage, Chronic Inflammation, published in Int J Pharm (2025) — summary generated from the PubMed abstract.
- 2025
Int J Pharm - Level BClinical TrialPubMed
The future of osteoarthritis treatment: exploring the potential of exosomes from adipose tissue-derived stem cells : a scoping review.
Clinical Trial on Osteoarthritis, Cartilage Damage, Chronic Inflammation, published in Bone Joint Res (2025) — summary generated from the PubMed abstract.
- 2025
Bone Joint Res - Level DAnimal StudyPubMed
Intra-Articular Injection of Adipose-Derived-MSC Exosomes and Hyaluronic Acid in Sheep Knee Osteoarthritic Models Enhances Hyaline Cartilage Regeneration.
Animal Study on Knee Osteoarthritis, Osteoarthritis, Cartilage Damage, published in Biomedicines (2025) — summary generated from the PubMed abstract.
- 2025
Biomedicines - Level DNarrative ReviewEurope PMC
Exosomes Reshape the Osteoarthritic Defect: Emerging Potential in Regenerative Medicine-A Review
Narrative Review on Osteoarthritis, Cartilage Damage, Chronic Inflammation, published in Int J Stem Cells (2024) — summary generated from the PubMed abstract.
- 2024
Int J Stem Cells5 citations - Level DAnimal StudyEurope PMC
Cartilage stem/progenitor cells-derived exosomes facilitate knee cartilage repair in a subacute osteoarthritis rat model
Animal Study on Osteoarthritis, Cartilage Damage, published in J Cell Mol Med (2024) — summary generated from the PubMed abstract.
- 2024
J Cell Mol Med11 citations - Level DNarrative ReviewEurope PMC
Strategies in product engineering of mesenchymal stem cell-derived exosomes: unveiling the mechanisms underpinning the promotive effects of mesenchymal stem cell-derived exosomes
Narrative Review on Osteoarthritis, Cartilage Damage, published in Front Bioeng Biotechnol (2024) — summary generated from the PubMed abstract.
- 2024
Front Bioeng Biotechnol7 citations - Level DLaboratory StudyEurope PMC
The Exosomes of Stem Cells from Human Exfoliated Deciduous Teeth Suppress Inflammation in Osteoarthritis
Laboratory Study on Osteoarthritis, Cartilage Damage, published in Int J Mol Sci (2024) — summary generated from the PubMed abstract.
- 2024
Int J Mol Sci5 citations - Level DAnimal StudyPubMed
Tropoelastin-Pretreated Exosomes from Adipose-Derived Stem Cells Improve the Synthesis of Cartilage Matrix and Alleviate Osteoarthritis.
Animal Study on Osteoarthritis, Cartilage Damage, Ligament Injury, published in J Funct Biomater (2023) — summary generated from the PubMed abstract.
- 2023
J Funct Biomater27 citations - Level DLaboratory StudyEurope PMC
A Bibliometric Analysis of Exosomes Therapy in the Treatment of Osteoarthritis from 2012 to 2022
Laboratory Study on Osteoarthritis, Cartilage Damage, published in J Pain Res (2023) — summary generated from the PubMed abstract.
- 2023
J Pain Res6 citations - Level DAnimal StudyPubMed
Hypoxia-treated adipose mesenchymal stem cell-derived exosomes attenuate lumbar facet joint osteoarthritis.
Animal Study on Osteoarthritis, Cartilage Damage, published in Mol Med (2023) — summary generated from the PubMed abstract.
- 2023
Mol Med22 citations
In-depth reviewed studies (full Thai translation)
Evidence system- Level ARandomized Controlled Trial
Cell-based versus corticosteroid injections for knee pain in osteoarthritis: a randomized phase 3 trial
A multicentre randomized trial in 480 knee osteoarthritis patients comparing SVF, BMAC and umbilical cord MSCs against corticosteroid injection. At 12 months no cell product outperformed the steroid control.
- 2023
- United States
- n = 480
- Level AMeta-analysis
Intra-articular Injection of Autologous Adipose-Derived Stem Cells or Stromal Vascular Fractions: Are They Effective for Patients With Knee Osteoarthritis? A Systematic Review With Meta-analysis of Randomized Controlled Trials
Pooled five RCTs comparing ADSC/SVF injection with placebo or hyaluronic acid, finding significant pain and function improvement at 6 and 12 months.
- 2023
- South Korea
- Level AMeta-analysis
Rapid-acting pain relief in knee osteoarthritis: autologous-cultured adipose-derived mesenchymal stem cells outperform stromal vascular fraction: a systematic review and meta-analysis
Analysed 31 studies with 1,406 patients: cultured ADMSCs reduced pain from month 3, whereas SVF reached significance only at 12 months.
- 2024
- South Korea
- n = 1406