Research database
SVF Research Library
Search 52,792 real PubMed studies on SVF and adipose-derived stem cells — 75 matching records.
75 results — page 1 of 4
- Level DAnimal StudyPubMed
Functionalized osteogenic extracellular vesicles derived from BMP9-stimulated mesenchymal stem cells (MSCs) effectively induce bone regeneration.
Animal Study, published in Biomaterials (2026) — summary generated from the PubMed abstract.
- 2026
Biomaterials - Level DAnimal StudyPubMed
Synovial inflammatory macrophage-derived extracellular vesicles exacerbate cartilage lesions with a FMRP-selectively sorted manner in osteoarthritis.
Animal Study on Osteoarthritis, published in Bone Res (2026) — summary generated from the PubMed abstract.
- 2026
Bone Res - Level ASystematic ReviewEurope PMC
Extracellular Vesicles for Treatment of Bone Resorption-Related Diseases in Animal Models: Systematic Review
Systematic Review, published in Calcif Tissue Int (2026) — summary generated from the PubMed abstract.
- 2026
Calcif Tissue Int - Level AMeta-analysisPubMed
Therapeutic effects of mesenchymal stem cells and their secretomes (extracellular vesicles) with bone-implant scaffolds for bone regeneration: A systematic review and network meta-analysis of preclinical studies.
Meta-analysis, published in Acta Biomater (2026) — summary generated from the PubMed abstract.
- 2026
Acta Biomater - Level DAnimal StudyEurope PMC
Small extracellular vesicles produced by homeostatic phenotype BMSC promote bone regeneration by transferring anti-senescent factor JMJD6
Animal Study, published in J Nanobiotechnology (2026) — summary generated from the PubMed abstract.
- 2026
J Nanobiotechnology1 citations - Level CProspective StudyEurope PMC
Atrophic Skeletal Muscle-Derived Extracellular Vesicles Transfer miR-125a-5p to Inhibit Bone Formation in Osteoporosis during Aging
Prospective Study, published in Adv Sci (Weinh) (2026) — summary generated from the PubMed abstract.
- 2026
Adv Sci (Weinh)1 citations - Level CProspective StudyEurope PMC
Extracellular Vesicles from Bone Marrow Mesenchymal Stem Cells Modulate Proliferation, Migration, and Chemosensitivity in Ovarian Cancer Cells
Prospective Study, published in Int J Mol Sci (2026) — summary generated from the PubMed abstract.
- 2026
Int J Mol Sci - Level DNarrative ReviewEurope PMC
Plant-derived extracellular vesicles in skin and bone tissue engineering: current status, challenges, and future perspectives
Narrative Review on Immune Modulation, published in Front Bioeng Biotechnol (2026) — summary generated from the PubMed abstract.
- 2026
Front Bioeng Biotechnol - Level DAnimal StudyEurope PMC
Senomorphic Small Extracellular Vesicles Delivered by a Tissue-Adhesive α-Lipoic-Acid Hydrogel Enable Immuno-Rejuvenation for Bone-Tendon Interface Regeneration
Animal Study on Tendon Injury, Rotator Cuff, Chronic Inflammation, Immune Modulation, published in Adv Sci (Weinh) (2026) — summary generated from the PubMed abstract.
- 2026
Adv Sci (Weinh) - Level DNarrative ReviewEurope PMC
Extracellular Vesicles as Orchestrators of Osteoimmunomodulation in Peri-Implantitis: Implications for Bone Regeneration
Narrative Review on Immune Modulation, published in Clin Implant Dent Relat Res (2026) — summary generated from the PubMed abstract.
- 2026
Clin Implant Dent Relat Res1 citations - Level AMeta-analysisEurope PMC
Therapeutic efficacy of mesenchymal stem cell-derived extracellular vesicles combined with injectable hydrogels in bone defect repair: a systematic review and meta-analysis of preclinical studies
Meta-analysis, published in J Biol Eng (2026) — summary generated from the PubMed abstract.
- 2026
J Biol Eng - Level DAnimal StudyEurope PMC
Bone-Targeting Microspheres Enable Sustained Release of CD301b<sup>+</sup> Macrophage-Derived Small Extracellular Vesicles to Promote Bone Repair
Animal Study on Immune Modulation, published in Theranostics (2026) — summary generated from the PubMed abstract.
- 2026
Theranostics - Level DAnimal StudyPubMed
Extracellular Vesicles (EVs) Mirror Their Source: Comparative Analysis of Bone Marrow-Derived and Adipose-Derived Stem Cells and EVs in Bone Regeneration.
Animal Study on Face & Skin, published in Cell Mol Bioeng (2026) — summary generated from the PubMed abstract.
- 2026
Cell Mol Bioeng - Level DAnimal StudyEurope PMC
T Cell-Derived Apoptotic Extracellular Vesicles Ameliorate Bone Loss via CD39 and CD73-Mediated ATP Hydrolysis
Animal Study on Chronic Inflammation, published in Int J Nanomedicine (2025) — summary generated from the PubMed abstract.
- 2025
Int J Nanomedicine7 citations - Level DLaboratory StudyEurope PMC
Small extracellular vesicles derived from auricular chondrocytes promote secretion of interleukin 10 in bone marrow M1-like macrophages
Laboratory Study on Cartilage Damage, Chronic Inflammation, published in Regen Ther (2025) — summary generated from the PubMed abstract.
- 2025
Regen Ther2 citations - Level DAnimal StudyPubMed
Extracellular Vesicles from Adipose-Derived Mesenchymal Stem Cells Improve Ligament-Bone Integration After Anterior Cruciate Ligament Primary Repair in Rabbit.
Animal Study on Ligament Injury, published in Biomolecules (2025) — summary generated from the PubMed abstract.
- 2025
Biomolecules3 citations - Level DNarrative ReviewEurope PMC
ECM-binding properties of extracellular vesicles: advanced delivery strategies for therapeutic applications in bone and joint diseases
Narrative Review on Cartilage Damage, Immune Modulation, published in Cell Commun Signal (2025) — summary generated from the PubMed abstract.
- 2025
Cell Commun Signal14 citations - Level CProspective StudyPubMed
Evaluation of the Safety and Regenerative Potential of Human Mesenchymal Stem Cells and Their Extracellular Vesicles in a Transgenic Pig Model of Cartilage-Bone Injury In Vivo - Preclinical Study.
Prospective Study on Osteoarthritis, Cartilage Damage, published in Stem Cell Rev Rep (2025) — summary generated from the PubMed abstract.
- 2025
Stem Cell Rev Rep5 citations - Level CProspective StudyEurope PMC
Engineered BMP2/BMP7 extracellular vesicles induce autocrine BMP release driving SMAD phosphorylation to promote bone formation
Prospective Study, published in NPJ Regen Med (2025) — summary generated from the PubMed abstract.
- 2025
NPJ Regen Med7 citations - Level AMeta-analysisEurope PMC
The effect of bone marrow mesenchymal stem cell-derived extracellular vesicles on bone mineral density and microstructure in osteoporosis: A systematic review and meta-analysis of preclinical studies
Meta-analysis, published in PLoS One (2025) — summary generated from the PubMed abstract.
- 2025
PLoS One - Level DLaboratory StudyPubMed
Extracellular Vesicles Present in Bone Marrow Mesenchymal Stromal/Stem Cell Conditioned Media Restore Spermatogenesis in Azoospermic Mice.
Laboratory Study, published in Int J Fertil Steril (2025) — summary generated from the PubMed abstract.
- 2025
Int J Fertil Steril - Level DNarrative ReviewEurope PMC
Mesenchymal Stem Cell-Derived Extracellular Vesicles: Seeking into Cell-Free Therapies for Bone-Affected Lysosomal Storage Disorders
Narrative Review on Osteoarthritis, Immune Modulation, published in Int J Mol Sci (2025) — summary generated from the PubMed abstract.
- 2025
Int J Mol Sci - Level DAnimal StudyPubMed
Injectable HAMA-CPC hydrogels loaded with high-yield 3D bioprinted adipose-derived stem cell small extracellular vesicles for increased bone repair.
Animal Study, published in J Nanobiotechnology (2025) — summary generated from the PubMed abstract.
- 2025
J Nanobiotechnology1 citations - Level DAnimal StudyEurope PMC
Irradiation of muscle precursor cells impairs the proliferative and angiogenic functions of their extracellular vesicles
Animal Study, published in Sci Rep (2025) — summary generated from the PubMed abstract.
- 2025
Sci Rep1 citations
In-depth reviewed studies (full Thai translation)
Evidence system- Level ARandomized Controlled Trial
Cell-based versus corticosteroid injections for knee pain in osteoarthritis: a randomized phase 3 trial
A multicentre randomized trial in 480 knee osteoarthritis patients comparing SVF, BMAC and umbilical cord MSCs against corticosteroid injection. At 12 months no cell product outperformed the steroid control.
- 2023
- United States
- n = 480
- Level AMeta-analysis
Intra-articular Injection of Autologous Adipose-Derived Stem Cells or Stromal Vascular Fractions: Are They Effective for Patients With Knee Osteoarthritis? A Systematic Review With Meta-analysis of Randomized Controlled Trials
Pooled five RCTs comparing ADSC/SVF injection with placebo or hyaluronic acid, finding significant pain and function improvement at 6 and 12 months.
- 2023
- South Korea
- Level AMeta-analysis
Rapid-acting pain relief in knee osteoarthritis: autologous-cultured adipose-derived mesenchymal stem cells outperform stromal vascular fraction: a systematic review and meta-analysis
Analysed 31 studies with 1,406 patients: cultured ADMSCs reduced pain from month 3, whereas SVF reached significance only at 12 months.
- 2024
- South Korea
- n = 1406